[Application and advances of exosome-hydrogel system in wound healing]. [PDF]
Qiu Y, Tan Q.
europepmc +1 more source
体外构建的皮肤模型InspectskinⅠ修复裸鼠全层皮肤缺损
【目的】 探讨胚胎来源表皮干细胞构建的人工皮肤模型InspectskinⅠ修复全层皮肤缺损的作用,为构建含皮肤附属结构的检验用皮肤奠定基础65377; 【方法】 将人羊膜和BMP-4定向诱导小鼠胚胎细胞分化为表皮干细胞,采用筏式培养在体外与PHBV和成纤维细胞共培养构建组织工程皮肤,经短暂培养后移植于裸鼠皮肤缺损创面,对移植物进行形态学和免疫组织化学观察65377; 【结果】 移植物可封闭皮肤缺损,在其表面可形成复层表皮样结构,真皮部分可见大小不等的由单层或复层上皮样细胞构成的管状和泡状结构65380 ...
doaj
[Emphasizing evolution of key technological elements in reconstructive surgery]. [PDF]
Zan T, Li Q.
europepmc +1 more source
[Proteomics analysis of the effect and mechanism of ADSCs on full-thickness skin defects in diabetic rats]. [PDF]
Gu Y, Chen YZ, Wang SY, Song HY, Bai N.
europepmc +1 more source
[Pathological characteristics of pigmented pretibial patches and vascular-immune abnormalities in diabetic patients]. [PDF]
Liu X, Chang B.
europepmc +1 more source
热休克蛋白 90 调节内皮一氧化氮合酶 (一个新近认识的心血管疾病调节物 9)
阐述热休克蛋白90(hsp90)作为一个心血管疾病新的调节物,在调节内皮一氧化氮合酶(eNOS)功能方面的作用:血管内皮一氧化氮(NO)主要来源于eNOS;eNOS同时有产生NO和氧阴离子自由基()的功能。NO与的平衡在调节心血管方面有着重要的作用,当这个平衡被打破时可导致多种心血管疾病的发生发展;实验发现,当hsp90与eNOS结合增加时,eNOS耦联产生NO,当hsp90与eNOS结合减少或结合后无发生结构改变时eNOS非耦联产生。进而提出深入探讨hsp90调节eNOS机制的必要性。
doaj
[Application of internal brace ligament augmentation technology in repair and reconstruction of cruciate ligament injuries]. [PDF]
Yang H +5 more
europepmc +1 more source
[Comprehensive analytical chemistry experiment: analysis of non-covalent interactions between double-stranded deoxyribonucleic acid and a natural drug by electrospray ionization mass spectrometry]. [PDF]
Ma L, Wang YH, Yuan YL, Wang SS.
europepmc +1 more source
[<i>Poria cocos</i> polysaccharide alleviates cyclophosphamide-induced intestinal barrier dysfunction and inflammation in mice by modulating gut flora]. [PDF]
Zhang Y +10 more
europepmc +1 more source
circATRNL1通过miR-21激活Smad4并抑制肺癌细胞的血管生成和转移标志物的表达
目的研究环状RNA趋化样1(circATRNL1)在非小细胞肺癌(NSCLC)中的机制,特别是其通过微小RNA(miR)-21调控Smad4信号及血管生成和转移标志物表达的影响。方法利用qRT-PCR检测circATRNL1和miR-21在正常肺上皮细胞和NSCLC细胞中的表达。通过双荧光素酶报告基因实验分析circATRNL1与miR-21的结合。对A549细胞进行circATRNL1过表达,并随后加入miR-21-mimic。通过Western blot法检测Smad4和p ...
张茜, 刘杰, 马红霞
doaj

