Results 101 to 110 of about 22,415 (183)
Evidence for a fisher‐designed solution to manta and devil ray bycatch in tuna fisheries
Conservation Biology, Volume 40, Issue 1, February 2026.Abstract Bycatch in global tropical tuna purse seine fisheries represents a significant source of mortality for manta and devil rays (mobulids), which are globally threatened. Use of best handling and rapid release practices on purse seine vessels can substantially reduce mortality and improve vulnerability status for mobulids.
Melissa R. Cronin +12 more
wiley +1 more source
Steroid Receptor Coactivator 1 Promotes Human Hepatocellular Carcinoma Progression by Enhancing Wnt/-catenin Signaling [PDF]
, 2016 SRC-1（Steroidreceptorcoactivator1）不仅是雄激素受体（androgenreceptor，AR）和雌激素受体（estrogenreceptor，ER)等激素受体的转录辅激活因子，而且能辅激活许多转录因子。SRC-1在乳腺癌和前列腺癌的发生发展进程中起着重要的作用，但是人们对于它在肝癌发生发展进程中所起的作用仍不清楚。在本文中，我们报道了SRC-1在62.5%（25/40）的肝癌组织样本（humanhepatocellularcarcinoma，HCC）中过表达。敲低SRC ...
童章炜
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International Journal of Applied Linguistics, Volume 36, Issue 1, Page 522-539, February 2026.ABSTRACT This paper examines the features of metadiscourse across different teacher moves in university linguistics classroom discourse and the teaching strategies reflected in its use. The results reveal that teachers employ diverse metadiscourse during classroom interactions to support student reasoning.
Jingjie Li, Wenjie Hu
wiley +1 more source
Characterization of Tmem59l knockout mice [PDF]
, 2015 TMEM59L是一种脑特异性高表达蛋白，其组织表达的特异性预示着TMEM59L可能在神经系统发育和神经退行性疾病发生中起着重要的作用，但是目前对于该蛋白的生理学和病理学功能都知之甚少，有必要在动物水平上加以深入研究。 我们最近获得了Tmem59l基因敲除小鼠。在本论文中，我们对该小鼠的表型进行了系统分析。我们发现Tmem59l-/-小鼠的出生遵从孟德尔遗传定律（+/+:+/-:-/-=72:136:65）。不过虽然Tmem59l-/-小鼠的形态大小以及脑的解剖结构与野生型小鼠没有显著差异 ...
高月鸿
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SWEET1‐mediated glucose transport is crucial for energy availability in Arabidopsis
New Phytologist, Volume 249, Issue 4, Page 1816-1830, February 2026.Summary The stress‐responsive hormone abscisic acid (ABA) is known for its inhibitory effects on various physiological processes, including seed germination, often resulting in energy deprivation. Interestingly, ABA‐induced germination inhibition can be alleviated by exogenous glucose (Glc), mimicking a functional interplay between ABA and sugar ...
Xueyi Xue +3 more
wiley +1 more source
Studies of Hyperaccumulation Mechanism of Eucalyptus grandis×E. urophylla to Manganese and Arabidopsis Transporter’s Functions on Metal Transportation and Signaling [PDF]
, 2015 重金属污染已经成为世界性问题，严重威胁人体健康，已引起广泛的关注。植物修复技术作为一种经济、环境友好的土壤污染治理途径，也引起越来越多人的兴趣。只有寻找到更多合适的超富集植物，并且深入研究重金属的耐受和吸收、转运途径，才能有效地控制重金属对作物的污染或者更好发挥超富集植物的修复潜能。 本论文通过矿区筛选，发现了新的诱导型锰超富集植物-巨尾桉。该植物可以在叶片富集大量锰元素。通过实验室水培和ICP-MS联用技术研究其对锰的耐受性、在各组织中的分异 ...
谢清清
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The role of Itch-mediated PPARγ ubiquitination in adipocyte differentiation [PDF]
, 2016 脂质过氧化物酶体增殖物激活受体γ（PPARγ）属于Ⅱ型核受体超家族成员，在脂肪及小肠组织中高表达。作为重要的核转录因子，PPARγ与视黄醇类X受体α(retinoidXreceptorα)形成异二聚体，随后结合在过氧化物酶体增殖物反应元件(PPRE)上，从而调控与脂肪分化、脂质代谢、炎症应答相关的靶基因表达，其功能的异常与糖尿病、肥胖等代谢疾病密切相关。临床上，PPARγ也被作为重要的药物靶点用于相关疾病的治疗。 PPARγ的翻译后修饰对其生物学功能有重要影响。我们发现C2-WW ...
何旺
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Shuitu Baochi Xuebao[目的] 为明晰京津风沙源区生态系统服务时空格局特征及识别其冷热点,评估京津风沙源区实施生态工程后的生态效益及生态影响。[方法] 基于京津风沙源区2000—2017年的遥感、气象、土壤、土地利用等数据,利用CASA(carnegie-ames-stanford approach)模型、InVEST(integrated valuation of ecosystem services and trade offs)模型、RWEQ(revised wind erosion equation)模型和RUSLE(
常瑨予 +6 more
doaj
舒张性心力衰竭患者血清BNP、CA125、C反应蛋白水平变化分析
Zhongguo shiyan zhenduanxue, 2012 心力衰竭（heart failure）是指在足够静脉回流的前提下心脏的收缩和舒张功能下降,心排出量减少,组织器官灌流不足,不能满足机体代谢需要,伴肺循环和/或体循环淤血的临床病理生理综合征[1]。心力衰竭是心血管疾病终末期的严重并发症 ...
朱继红
doaj
Structural and mechanistical studies of the nuclear import of KAT8 by importin α [PDF]
, 2015 作为真核细胞的显著特征，核膜包裹的细胞核将核内的遗传物质和转录单元与细胞质内的翻译单元和代谢单元分割了开来，这种分割方便了细胞对包括基因表达、信号传导和细胞周期等众多细胞生理活动的调控。特定组分在细胞质和细胞核间的选择性双向运输就是这种调控的一项关键特征，大分子货物蛋白从细胞质向细胞核定向运输需要货物蛋白的核定位信号NLS、识别并结合NLS的接头蛋白细胞核输入蛋白IMPα及载体分子细胞核输入蛋白IMPβ三方的协调作用 ...
王瑞
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