Results 61 to 70 of about 25,036 (174)
免疫细胞常处于病理性或生理性缺氧环境中,缺氧可以明显影响免疫细胞的多种生物学功能。在诸多病理情况下,如感染、炎症、创伤、休克、肿瘤、器官移植等,常发生缺氧,从而引起免疫细胞缺氧反应和功能改变。现就此作一综述。1细胞氧感受器细胞缺氧反应涉及细胞内氧感受机制 ...
李蕾, 王发龙, 陈国千
doaj
This paper summarized the nursing a stroke patient with shoulder-hand syndrome treated by ultrasound-pharmaceutical transdermal therapy combined with acupoint application.
SHEN Yanli (申艳丽), GAO Bo (高波)
doaj +1 more source
Mechanistic and Functional Studies of Rab7 Phosphorylation [PDF]
Rab7调控着从内体到溶酶体以及从内体到高尔基体的囊泡运输过程;也参与了自噬、吞噬过程;同时还调节着溶酶体及其相关细胞器的生成过程。Rab7的功能受到各种相互作用因子的调控;Rab7的功能异常会导致包括神经退行性疾病和肿瘤在内的多种疾病。前期实验发现Rab7与Src在早期内体和晚期内体共定位,另有报道v-Src可激活Rab7,但是Src对Rab7的调节机制尚不清楚。 本研究发现Src、Blk等酪氨酸激酶可磷酸化修饰Rab7,其磷酸化位点为第183位酪氨酸残基 ...
林晓思
core
ABSTRACT The development of high‐efficiency, stable, and scalable perovskite solar cells/perovskite solar modules (PSCs/PSMs) highly depends on the performance and cost‐effectiveness of functional layers such as electron transport layers (ETLs) and hole transport layers (HTLs).
Baochang Wang +11 more
wiley +1 more source
Peri-operative nursing of lung cancer patients with pulmonary function moderately decrease
[目的]探讨肺通气功能中度减退肺癌病人围手术期护理措施。[方法]回顾性总结我院行手术治疗的41例肺功能减退的肺癌病人术前肺功能与术后并发症发生情况。[结果]该组病人术后常见低氧血症(41.5%),心律失常或心功能不全(26.8%),肺部感染(26.8%)等一般并发症,呼吸衰竭、心力衰竭等严重并发症的发生率为7.3%。[结论]做好围手术期充分、详细的护理措施对于预防并发症的发生或减轻并发症程度、降低围手术期病死率及术后的恢复起着关键的作用。
邹秀梅 +3 more
doaj
The Role of BIN1 in Alzheimer’s Disease [PDF]
阿尔茨海默症(Alzheimer’sdisease,AD)是与年龄相关的神经退行性疾病,其主要的病理学特征为由β-淀粉样蛋白(-amyloid,Aβ)聚集产生的老年斑(senileplaues,SP)以及由异常磷酸化的tau蛋白组成的神经纤维缠结(neurofibrillarytangles,NFTs)。Aβ是由淀粉样前体蛋白(-amyloidprecursorprotein,APP)经过β-分泌酶和γ-分泌酶的依次顺序剪切而产生 ...
牛萌萌
core
ABSTRACT MCrAlX coatings are widely used as bond coats in thermal barrier coating systems to protect turbine blades from high‐temperature oxidation. However, their oxidation resistance is often restricted by uncontrolled microstructures, surface roughness, and aggregation of reactive elements (REs). In this study, high‐repetition‐rate femtosecond laser
Wei Qian +7 more
wiley +1 more source
猕猴在解剖、生理、生化各方面与人类最为相似,其实验结果易外推于人,是替代人体最理想的实验动物。福建山区辽阔,野生猕猴资源丰富,为了更好地利用猕猴作为人类疾病的实验动物模型,进一步了解正常野生猕猴各项生理生化指标,我们特对捕自福建的猕猴进行肝功能指标测定,旨在建立一套福建野生猕猴正常肝功能指标,以保证实验的准确性。
周斌华 +5 more
doaj
CDK5 promotes HCC genesis and promotes cell migration by TPX2 [PDF]
我国是世界上肝癌最高发的国家之一,由于其较高的发病率和致死率,严重威胁人民的健康,但目前大多数肝癌患者仍难以获得早期诊断及有效的治疗。细胞周期蛋白依赖性激酶5(cyclin-dependentkinase5,CDK5)是周期素依赖蛋白激酶家族的特殊成员,近年来发现其在肿瘤发生发展中起着关键的作用。CDK5通过与激活因子p35或p39结合后活化并磷酸化一系列下游分子,参与肿瘤细胞增殖、迁移、粘附、凋亡、细胞周期调控等。但CDK5对肝癌细胞功能的影响及其在肝癌中的调控机制还不清楚 ...
王付强
core
ABSTRACT NiFe‐based MIL‐55 metal‐organic frameworks (MOFs) face challenges in achieving atomically precise composition and reliable methods for uniform growth. This study addresses these challenges by applying a slow evaporation crystallization technique to crude colloidal MIL‐55 products from hydrothermal synthesis, resulting in highly uniform ...
H. R. Haris +10 more
wiley +1 more source

