[Preoperative Evaluation of Cervical Lymph Node Metastasis in Patients With Hashimoto's Thyroiditis Combined With Thyroid Papillary Carcinoma Using Machine Learning and Radiomics-Based Features: A Preliminary Study]. [PDF]
Sichuan Da Xue Xue Bao Yi Xue Ban目的 利用机器学习（machine learning, ML）模型分析桥本甲状腺炎（Hashimoto thyroiditis, HT）合并甲状腺乳头状癌（papillary thyroid carcinoma, PTC）患者的甲状腺肿瘤的二维超声图像提取的影像组学和临床特征，探讨其术前无创识别该类患者颈部淋巴结转移（lymph node metastasis, LNM）的能力。 方法 纳入HT合并PTC患者528例，以病理结果为金标准划分为存在颈部淋巴结转移组和不存在颈部淋巴结转移组 ...
Fu R +7 more
europepmc +2 more sources
Zhongshan Daxue xuebao. Yixue kexue ban目的探讨高尔基运输1A蛋白 （GOLT1A）在甲状腺癌细胞中的表达水平及其对甲状腺癌细胞增殖、迁移、侵袭和上皮-间充质转化（EMT）的影响。方法利用在线数据库肿瘤免疫评估资源（TIMER）、阿拉巴马大学伯明翰分校癌症数据分析（UALCAN）和表达谱交互分析2（GEPIA2）在线分析GOLT1A在甲状腺癌织中的表达。采用实时荧光定量PCR方法和Western blot检测人甲状腺癌细胞中GOLT1A的表达水平，CCK-8实验、集落形成实验和Transwell实验检测GOLT1A表达对人甲状腺癌细胞增殖 ...
柯淑红, 徐朱俊, 周杨, 郑承红
doaj +3 more sources
Zhongshan Daxue xuebao. Yixue kexue ban, 2017 摘要：【目的】探讨甲状腺乳头状癌的淋巴结转移规律，分析其影响因素。【方法】回顾性分析我院自2011年1月至 2015年12月手术治疗甲状腺乳头状癌病人375 例的临床资料，对其原发灶特点、淋巴结转移规律进行了总结。【结果】本组 患者均为甲状腺乳头状癌，颈部淋巴结总转移率为67.47%，中央组淋巴结转移率为64.27%，颈侧组淋巴结转移率为 36.53%。原发灶肿瘤直径大于1 cm、肿瘤突破包膜、侵犯肌肉时颈淋巴结转移发生率明显升高（P < 0.05）。【结论】甲状腺乳 ...
张鹏 +6 more
doaj +2 more sources
基于ACR TI-RADS分类对甲状腺乳头状癌淋巴结转移风险模型的预测 [PDF]
Zhongshan Daxue xuebao. Yixue kexue ban, 2018 【目的】应用美国放射学会（ACR）甲状腺影像报告及数据系统（ACRTI-RADS2017）对甲状腺乳头 状癌患者转移风险进行评估，提高超声对甲状腺转移癌检出率。【方法】回顾分析经病理确诊的甲状腺乳头状癌 163例，根据术后N分期分为转移与非转移2组，对照临床和病理特征，对ACRTI-RADS评分与甲状腺乳头状癌 患者发生淋巴结转移的关系进行单因素和多因素分析。【结果】发生淋巴结转移患者TI-RADS评分为12.0 （10.0，14.0），高于未发生转移的患者（P＝0.003 ...
何学森 +3 more
doaj +2 more sources
Clinical study on high-risk factors for contralateral lymph node metastasis in unilateral papillary thyroid carcinoma [PDF]
, 2023 Background and purpose: The occurrence of lymph node metastasis in papillary thyroid cancer (PTC) can have adverse effects on the prognosis of patients. This study aimed to investigate risk factors related to the occurrence of contralateral central lymph
YUAN Xinyue, YAO Yao, CHENG Shuai, ZHENG Xin, ZHANG Yuan
core +1 more source
Predictive Value of Combined Use of Ultrasonographic Indicators for Central Lymph Node Metastasis in Papillary Thyroid Carcinoma [PDF]
, 2022 BackgroundThe treatment scheme for papillary thyroid carcinoma (PTC) patients is related to whether lymph node metastasis is prevalent or not. The routine ultrasound indicator used alone has proven to have a low sensitivity to predict the presence of ...
ZHANG Xiaomei, KANG Yanfei, SANG Tian, CHENG Jing, LI Qiaoli, CAO Yuwen, MA Jinmei, SHI Linan, LI Wenxiao, LI Jun
core +1 more source
Analysis and realization of pathology diagnosis on intraoperative frozen sections of papillary thyroid carcinoma [PDF]
, 2014 目的 探讨术中冷冻切片在甲状腺肿瘤手术中的应用，提高甲状腺乳头状癌术中冷冻病理诊断的准确率。方法 回顾性观察我科43例甲状腺乳头状癌患者的术中冷冻切片。结果 术中冷冻切片诊断甲状腺乳头状癌43例，确诊率为100%。结论 为提高术中冷冻切片病理诊断的准确性，必须加强与临床医师沟通，详细了解患者的临床资料，正确全面的取材，掌握甲状腺乳头状癌的病理诊断及鉴别要点，提高冷冻切片质量。Objective:To explore the application of intraoperative frozen
Che, Chao +6 more
core +3 more sources
Ultrasound-based Thyroid Nodule Malignancy Risk Stratification in Differentiating Benign and Malignant Thyroid Nodules：a Comparative Analysis between the C-TIRADS and ATA Guidelines [PDF]
, 2022 BackgroundThe 2020 Chinese guidelines for ultrasound malignancy risk stratification of thyroid nodules: the C-TIRADS (C-TIRADS for short) put forward a method for stratifying the malignancy risk of thyroid nodules, but there are few studies about its ...
LI Jian, YIN Yanhua, QI Jianguo, WANG Zhou, REN Yongfeng, WANG Shanshan, ZHANG Weili, WANG Xiaojun, TANG Kun
core +1 more source
Analysis of tumor-related features of non-small cell lung cancer based on TCR repertoire workflow [PDF]
, 2023 Objective·To explore the immune-related characteristics of non-small cell lung cancer (NSCLC), discover potential tumor markers in V-J genes, and lay the foundation for establishing a TCR-antigen recognition prediction model.Methods·A total of 704 NSCLC ...
LIU Zhenhao +5 more
core +1 more source
Clinical application analysis of Da Vinci Xi robot in thyroid surgery using a gasless, unilateral axillary approach [PDF]
, 2023 Background and purpose: Robotic thyroid surgery has been carried out worldwide since Kang first applied it to the thyroid in 2007. The proportion of axillary approach is increasing rapidly in China due to the continuous verification of safety ...
SHI Rongliang, ZHANG Tingting, WANG Yu, NI Zhaoxian, WANG Hui, WANG Yulong, WEI Wenjun, XIANG Jun, QU Ning, LU Zhongwu, FAN Juan, GU Weijin, JI Qinghai
core +1 more source