Preliminary application of improved 3D printed pathological section box to assisting stitching pathological images of bone tumor [PDF]
, 2023 Objective·To explore the feasibility of applying improved pathological section boxes based on image post-processing and 3D printing technology to assisting artificial intelligence (AI) in stitching pathological images of bone tumors.Methods·Bone tumor ...
AI Songtao +6 more
core +1 more source
甲状腺乳头状癌雌激素受体β表达及其 5′非翻译区甲基化 [PDF]
, 2020 【目的】研究甲状腺乳头状癌（PTC）中雌激素受体β基因（ERβ）表达及 5′非翻译区甲基化状态，探讨ERβ在 PTC 中低表达的原因。【方法】应用 Western blot 和免疫组织化学染色法检测正常甲状腺细胞Nthy-ori3-1、PTC 细胞 BCPAP 以及正常甲状腺组织、甲状腺结节性增生组织和 PTC 组织ERβ蛋白表达；应用 qRT-PCR 检测各细胞和组织中 ERβ mRNA（0K-1）、ERβ mRNA（0N-1）和总 ERβ mRNA 表达水平；亚硫酸氢盐测序分析各细胞和组织中 ERβ
刘智敏, 苟茜, 许琳婉
core
Study on the Nomogram Model Based on Dual-energy Computed Tomography for Predicting Lymph Node Metastasis in Papillary Thyroid Carcinoma [PDF]
Objective: This study aimed to evaluate the effectiveness of a nomogram model based on dual-energy computed tomography (CT) quantitative parameters combined with clinical information for distinguishing metastatic from non-metastatic lymph nodes in ...
Bo GAO +9 more
core +1 more source
FNAB联合BRAF V600E基因检测术前诊断甲状腺乳头状癌的价值
Zhongguo shiyan zhenduanxue, 2023 目的 探讨超声引导下细针穿刺(FNAB)、BRAF V600E基因突变检测单一及联合诊断对甲状腺乳头状癌(PTC)术前诊断的价值。方法 选取2020年1月至2022年10月于河南科技大学第一附属医院甲状腺外科行甲状腺手术且术前同时行FNAB及BRAF突变检测的患者216例，其中9例患者穿刺了甲状腺双叶结节。以术后病理结果为金标准，对比两种术前诊断方法单一及联合诊断的价值。结果 共225枚结节，术后病理诊断为甲状腺乳头状癌的214例，诊断为结节性甲状腺肿等甲状腺良性病变的结节11枚，BRAF ...
乔楠, 王明军
doaj
Advances in basic research, clinical diagnosis and treatment of thyroid cancer in 2022 [PDF]
, 2023 Thyroid cancer is a common malignancy of the endocrine system with a significantly increased incidence in recent years. Surgical treatment is the primary treatment, followed by endocrine therapy and radionuclide therapy according to the clinical ...
QU Ning, WANG Yuting, MA Ben, WANG Yu
core +1 more source
PES1上调ERα/ERβ蛋白比率促进甲状腺乳头状癌细胞增殖和侵袭迁移 [PDF]
, 2020 目的研究PES1通过上调ERα/ERβ蛋白比率促进甲状腺乳头状癌（PTC）细胞增殖和侵袭转移的分子机制。方法用免疫组化法检测PES1、ERα和ERβ在正常甲状腺组织以及PTC组织中的表达情况；用Western blot法分别检测正常甲状腺细胞株Nthy-ori3-1和PTC细胞株BCPAP和K1中PES1、ERα 和 ERβ的表达情况，以及PES1过表达、PES1下调时对Nthy-ori3-1细胞和BCPAP细胞中ERα、ERβ蛋白表达比率的影响；用MTT以及Transwell小室法检测PES1 ...
刘智敏, 程龙, 许琳婉, 邱伊波
core
Zhongshan Daxue xuebao. Yixue kexue ban, 2016 摘 要: 【目的】 探讨前列腺素E受体4(EP4)对人甲状腺乳头状癌TPC-1细胞生长的影响?【方法】 体外培养人甲状腺乳头状癌细胞株TPC-1及人甲状腺滤泡上皮细胞株Nthy-ori 3-1,Nthy-ori 3-1细胞作为对照,用ELISA法检测细胞上清液中前列腺素E2(PGE2)含量;用实时荧光定量PCR法检测四种前列腺素E2受体亚型(EP1?EP2?EP3?EP4)mRNA表达水平;用Western Blot法检测EP1-4?PKA及PI3K两种亚型(p110α?p110γ)蛋白的表达情况 ...
doaj +1 more source
, 2019 【目的】探究甲状腺乳头状癌（PTC）颈侧区淋巴结转移的临床特征。【方法】回顾性分析皖南医学院附属弋矶山医院2011年6月1日至2018年5月30日收治的PTC患者临床资料。【结果】本研究共纳入241例病例。术后常规病理证实颈侧区淋巴结转移率73.44%（177/241）。与颈侧区淋巴结无转移的PTC患者相比，伴颈侧区淋巴结转移的PTC患者年龄偏小，多为女性，癌肿直径较大，颈中央区淋巴结转移数目较多，超声及CT检查积分更高。而BMI指数、桥本氏甲状腺炎病史及甲亢病史对PTC颈侧区淋巴结转移率无显著性影响。【
方芳
core
Integrated diagnosis and treatment pathway for papillary thyroid carcinoma （initial diagnosis）： expert consensus of Thyroid Center of the Third Affiliated Hospital of Sun Yat-sen University [PDF]
In recent years， the incidence of papillary thyroid carcinoma （PTC） in China has increased significantly. Thus， it is necessary to standardize the procedures of diagnosis， treatment and follow-up.
Thyroid Center of the Third Affiliated Hospital of Sun Yat-sen University
core +1 more source
Probabilistic assessment of the exposure risk to dietary perchlorate in the Chinese population from general and key areas [PDF]
, 2023 ObjectiveTo assess the exposure and health risks from perchlorates in food and tea among Chinese residents grouped by key and common areas.MethodsPerchlorate content data for food and tea in China were collected from the literature.
CHEN Qiuyu +4 more
core +1 more source