Graves氏病患者血清甲状腺刺激免疫球蛋白的测定及其在临床上的意义 [PDF]
Zhongshan Daxue xuebao. Yixue kexue ban, 1983 弥漫性甲状腺肿伴甲状腺功能亢进(Graves氏病,以下简称弥漫性甲亢)是甲状腺功能亢进症中最常见的类型,其发病机理与机体免疫功能障碍有密切关系。国外不少资料表明,在多数弥漫性甲亢患者血中存在一种异常的甲状腺刺激物——甲状腺刺激免疫球蛋白(Thyroid stimulating immunoglobulin,TSI)。但国内报告很少。本文对55例弥漫性甲亢患者和15例正常人进行了血清TSI测定,探讨它在本病发病中的作用;并对TSI测定的临床意义,作初步的分析。
冷松
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甲状腺功能低下对胚胎时期大鼠皮质下视、听中枢细胞增殖迁移的影响 [PDF]
Zhongshan Daxue xuebao. Yixue kexue ban, 1991 报告采用放射自显影术用~3H-TdR为示踪剂,以标记率为指标,对胎龄13、15、17、19及21天的正常与甲状腺功能低下大鼠皮质下视、听中枢细胞的增殖和迁移进行了观察结果,表明,甲状腺功能低下胎鼠的耳蜗背核、耳蜗腹核、内侧膝状体、下丘的细胞增殖和迁移速度在胎龄19及21天时低于正常对照组;甲状腺功能低下胎鼠外侧膝状体和上丘细胞增殖和迁移速度在胎龄17、19及21天均慢于正常对照组。
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Research progress on effects of PM2.5 exposure during pregnancy on maternal and infant thyroid function [PDF]
, 2022 Ambient air pollution has become a widespread global public health problem. As one of the main components of ambient air pollution, fine particulate matter (PM2.5), with its small diameter and large surface area, can carry a variety of toxic substances ...
Chenchen WANG +3 more
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28~36周早产儿生后3~21天血FT3、FT4、TSH变化分析 [PDF]
, 2021 目的分析28~36周早产儿生后3~21 d FT3、FT4、TSH变化的特征。方法回顾性分析2018年7月至2019年6月中山大学附属第三医院新生儿科住院的236例28~36周早产儿的临床资料，包括甲状腺功能检查（FT3、FT4和TSH）、胎龄、性别、出生体质量、出生身长、检查日龄、辅助生殖方式、单胎或多胎、母亲甲状腺疾病和母亲妊娠期糖尿病，比较早产儿3~7 d与8~21 d FT3、FT4和TSH水平的差异；分析影响早产儿FT3、FT4和TSH水平的独立因素；比较不同胎龄早产儿FT3 ...
代群 +6 more
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Association between Subclinical Hypothyroidism and Cardiac Autonomic Neuropathy in Type 2 Diabetes Mellitus [PDF]
, 2022 BackgroundCardiac autonomic neuropathy (CAN) is a common and severe chronic diabetic complication, whose association with thyroid function has rarely been reported.ObjectiveTo investigate the association between subclinical hypothyroidism and CAN in type
ZHAO Lei, LI Ruqiang, YUAN Mingxia
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Iodine supplementation for preventing iodine deficiency disorders in children and adolescents [PDF]
, 2023 This is a protocol for a Cochrane Review (intervention). The objectives are as follows: To assess the efficacy and safety of iodine supplementation for preventing iodine deficiency in children and ...
Chi, Yuan +7 more
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A meta-analysis of the effects of levothyroxine dose adjustment on maternal and infant outcomes in pregnant women with hypothyroidism [PDF]
, 2023 Objective·To evaluate the effects of levothyroxine (L-T4) dose adjustment according to the level of thyroid stimulating hormone (TSH) on maternal and infant outcomes in the pregnant women with hypothyroidism by meta-analysis.Methods·China National ...
CHEN Hui, YAO Yijin, ZHU Weiyi
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Interpretation of the 2015 guidelines on diagnosis and treatment of endogenous subclinical hyperthyroidism by the European Thyroid Association [PDF]
, 2017 亚临床甲状腺功能亢进症在临床中很常见,但对其危害及处理有很大的争议。欧洲甲状腺学会根据现有的临床证据,公布了内因性亚临床甲状腺功能亢进症诊治指南; 。指南强调,要确立持续性亚临床甲状腺功能亢进症的诊断,明确其病因,按照其进展为临床甲亢、发生不良心血管事件及骨质疏松风险进行危险分层,以指导临床; 处理。Endogenous subclinical hyperthyroidism (Endo SHyper) is a common form of; thyroid diseases.
刘超, 李学军, 肖方森
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桥本甲状腺炎细胞病理分级与甲状腺功能和Hb、RBC、WBC及PLT的相关性研究
Zhongguo shiyan zhenduanxue, 2021 目的通过细针穿刺细胞病理学对桥本甲状腺炎(Hashimoto’s thyroiditis,HT)进行分级,并进一步探讨甲状腺功能、主要血常规参数与细胞学分级之间的相关性。方法对39名经细胞病理学检查确诊为HT的患者的病理涂片进行回顾性分析,并根据细胞学分级标准进行分级。患者均完成游离甲状腺素(FT4)、游离三碘甲状腺氨酸(FT3)、促甲状腺激素(TSH)、甲状腺球蛋白抗体(TGAb)、甲状腺过氧化物酶抗体(TPOAb)及血常规等检查。结果大多数患者为桥本甲状腺炎1级(56.4%),其次是2级(28.2%)
王春, 石娜, 王崇高, 王康
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Effects of T4 on the Synthesis of Cardiolipin and TREK-1 , KCNQ1 Potassium Channels in Hyperthyroid Heart Disease [PDF]
, 2016 甲状腺功能亢进性心脏病是指在甲状腺功能亢进症时，甲状腺激素对心脏的直接或间接作用所致的心脏扩大、心功能不全、心房纤颤、心绞痛甚至心肌梗死等一系列心血管症状和体征的一种内分泌代谢紊乱性心脏病，已证实心磷脂（Cardiolipin，CL）在甲亢性心脏功能变化中起作用。心磷脂合酶（CLS）是心磷脂从头合成过程的关键酶，而磷脂酶A2(PLA2)在心磷脂重构过程中发挥重要作用。双孔钾通道TREK-1在静息膜电位的形成、复极过程和调控细胞兴奋性方面发挥重要作用，KCNQ1钾通道是心肌细胞复极化平台期的重要成分 ...
郭凡
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