Results 11 to 20 of about 4,641 (149)

Retrospective cohort analysis comparing changes in blood glucose level and body composition according to changes in thyroid‐stimulating hormone level 促甲状腺激素水平变化对血糖和身体成分影响的回顾性队列分析

open access: yesJournal of Diabetes, Volume 14, Issue 9, Page 620-629, September 2022., 2022
Highlights Body composition changes were identified by baseline thyroid‐stimulating hormone (TSH) and difference in TSH (∆TSH) levels. A positive correlation between ∆TSH and ∆glucose was established. Patients with high TSH levels in the euthyroid state need muscle and fat management.
Hyunah Kim   +5 more
wiley   +1 more source

Subsequent perinatal outcomes of pregnancy with two consecutive pregnancies with gestational diabetes mellitus: A population‐based cohort study 连续两次妊娠合并妊娠期糖尿病的围产期结局:一项基于人群的队列研究

open access: yesJournal of Diabetes, Volume 14, Issue 4, Page 282-290, April 2022., 2022
HighlightsTo summarize, we found that the incidence of complications in subsequent pregnancies in women with recurrent GDM did not differ from that in their index pregnancies. There is a high incidence of thyroid disease in women with recurrent GDM in this study.
Yanni Guo   +5 more
wiley   +1 more source

Are psychiatric disorders associated with thyroid hormone therapy in adolescents and young adults with type 1 diabetes? 青少年和青壮年1型糖尿病患者的精神障碍与甲状腺激素治疗有关吗?

open access: yesJournal of Diabetes, Volume 13, Issue 7, Page 562-571, July 2021., 2021
Highlights Several psychiatric disorders were associated with levothyroxine therapy (LT4). Depression, anxiety disorders, and attention‐deficit/hyperactivity disorder showed the strongest relation to LT4. Thyroid autoimmunity itself (no LT4) was not associated with psychiatric disorders.
Alexander Eckert   +9 more
wiley   +1 more source

International clinical practice recommendations on the definition, diagnosis, assessment, intervention, and psychosocial aspects of developmental coordination disorder – Chinese (Mandarin) translation

open access: yesDevelopmental Medicine &Child Neurology, Volume 61, Issue 3, Page E1-E35, March 2019., 2019
目的 本国际临床指南由欧洲残疾儿童学会(the European Academy of Childhood Disability,EACD)牵头制定,旨在解决发育性协调障碍(developmental coordination disorder,DCD)的定义、诊断、评估、干预以及与社会心理方面的临床应用关键问题。 方法 本指南针对五个领域的关键问题,通过文献综述和专家团队的正式讨论达成共识。为保证指南的循证基础,以“机制”、“评估”和“干预”为检索词, 对2012年更新以来提出的最新建议以及新增的“社会心理问题”和“青少年/成人”为检索词进行检索。根据牛津大学循证医学中心证据等级 (证据水平 [level of evidence, LOE]1–4) 将结果进行分类,最终转化为指南建议。并由国际 ...
Jing Hua   +6 more
wiley   +1 more source

The effect of thyroid hormone on GLUT4 and its relationship with cardiolipin [PDF]

open access: yes, 2016
课题组前期的研究结果表明,甲亢性心脏功能变化与心磷脂关系密切,本研究拟从GLUT4(Glucosetransporter4,葡萄糖转运蛋白4)变化的角度进一步探讨心磷脂在甲亢中的作用。 心脏作为一个高能量代谢的组织,主要通过线粒体中氧化磷酸化产生ATP来提供能量,并且对葡萄糖体现出高度依赖性。而GLUT4是糖转运体蛋白家族中的一员,在葡萄糖的非ATP-依赖膜转运过程中起着重要作用。因此,对于以高代谢为主要变化的甲亢,探讨GLUT4是有必要的。而且,文献报道甲状腺激素可促进心肌组织中GLUT4的表达 ...
孙婷
core  

妊娠合并甲状腺功能减退诊治研究进展

open access: yesZhongguo shiyan zhenduanxue, 2020
随着社会的不断发展,人们生活水平的提高,人们对妊娠时期的疾病越来越关注,其治疗手段参差不齐。现如今,有报道妊娠合并甲状腺功能减退的疾病发生率逐年升高,越来越多的妊娠人群患有甲状腺功能减退症状,其能够造成对患者的生命健康的严重威胁[1]。距今为止,针对妊娠时期孕妇的甲状腺功能的筛查仍未做出具体规范,现针对其对母婴的影响以及诊断标准问题进行综述。1妊娠期甲状腺功能孕妇甲状腺内分泌在妊娠期间可能出现一些生理变化。甲状腺代谢发生改变 ...
归倩   +4 more
doaj  

The effect of thyroxine on ATP-sensitive potassium channels and cardiolipin synthesis [PDF]

open access: yes, 2015
甲亢性心脏病(HyperthyroidHeartDisease,HHD)是甲状腺功能亢进(Hyperthyrodism)的严重并发症,严重危害患者的生命健康,但其机制尚未完全阐明。心磷脂(Cardiolipin,CL)是主要位于线粒体内膜的特殊磷脂,在维持正常的线粒体功能中具有至关重要的作用。本课题组前期研究表明甲亢小鼠心脏中心磷脂含量升高,并且心磷脂参与甲亢性心脏病的病理过程。此外,文献资料显示甲亢会引起心磷脂侧链的C18:2的丢失,同时引起侧链中多不饱和脂肪酸含量的增多 ...
侯琦
core  

亚甲基四氢叶酸还原酶基因多态性及甲状腺功能与妊娠期糖尿病的相关性

open access: yesZhongguo shiyan zhenduanxue, 2021
目的 探讨亚甲基四氢叶酸还原酶(MTHFR)基因C677T位点多态性及甲状腺功能与妊娠期糖尿病的相关性。方法 选取承德医学院附属医院51名患有妊娠期糖尿病的孕妇作为病例组,同期60名正常妊娠孕妇作为对照组。运用PCR-荧光探针法检测两组的MTHFR C677T基因多态性。采用全自动免疫分析仪进行甲状腺功能指标的测定。应用全自动生化分析仪检测两组研究对象的血浆同型半胱氨酸水平。对比两组孕妇甲状腺功能、同型半胱氨酸和MTHFR基因型分布情况,探讨MTHFR基因多态性及甲状腺功能与妊娠期糖尿病的关系。结果 ...
王玲玲   +4 more
doaj  

甲状腺功能减退症及其替代治疗对血糖和血脂代谢的影响 [PDF]

open access: yes, 2018
目的探讨甲状腺功能减退症及其替代治疗对血糖和血脂代谢的影响。方法对22例甲状腺功能减退症患者(甲减组)及16例甲状腺功能正常者(正常组)分别在治疗前及治疗后6个月测定促甲状腺素(TSH)、游离三碘甲腺原氨酸(FT3)、血清游离甲状腺素(FT4)、空腹胰岛素(FINS)、空腹血糖(FBG)、总胆固醇(TC)、三酰甘油(TG)。胰岛素抵抗使用稳态模型评估的胰岛素抵抗指数(HOMA-IR)进行评估。结果治疗前甲减组和正常组对比,FBG、FINS、HOMA-IR、TC和TG比较差异均无统计学意义(P>0.05)。
吴娟, 李津, 王生燕, 黄滨
core  

Associated Risk Factors in Group B Streptococcus Infection During Pregnancy [PDF]

open access: yes, 2022
BackgroundGroup B streptococcus (GBS) infection can give rise to intrauterine infection during pregnancy and postpartum endometritis, and increase the risk of premature birth or stillbirth.
HUANG Yan, WANG Mingying, FENG Junyan, ZHANG Jie
core   +1 more source

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