Results 71 to 80 of about 3,425 (144)
Current status and prospect of diagnosis and treatment of bone metastasis of thyroid cancer [PDF]
For differentiated thyroid cancer (DTC), which accounts for over 90% of cases and usually has a good prognosis, bone metastasis is not only the main threat to patients’ survival and quality of life, but also a difficult problem that needs to be solved ...
ZHAO Yihan, LI Ruochen, LIN Yansong
core +1 more source
Zhongshan Daxue xuebao. Yixue kexue ban, 2017 摘要：【目的】探讨甲状腺乳头状癌的淋巴结转移规律，分析其影响因素。【方法】回顾性分析我院自2011年1月至 2015年12月手术治疗甲状腺乳头状癌病人375 例的临床资料，对其原发灶特点、淋巴结转移规律进行了总结。【结果】本组 患者均为甲状腺乳头状癌，颈部淋巴结总转移率为67.47%，中央组淋巴结转移率为64.27%，颈侧组淋巴结转移率为 36.53%。原发灶肿瘤直径大于1 cm、肿瘤突破包膜、侵犯肌肉时颈淋巴结转移发生率明显升高（P < 0.05）。【结论】甲状腺乳 ...
张鹏 +6 more
doaj
An Update on Reactive Carbonyl Species and Their Effects on the Formation of Chemical Hazards during Food Processing [PDF]
Reactive carbonyl species (RCSs) are a class of active aldehydes and ketones. RCSs are formed in the body through a serious of reactions such as lipid oxidation and glycolysis as well as through lipid oxidation and the Maillard reaction during food ...
TANG Jialing, HUI Teng, HAN Guoquan
core +1 more source
BRAFV600E突变与甲状腺乳头状癌临床病理特征关系的研究进展
Zhongguo shiyan zhenduanxue甲状腺癌是内分泌系统最常见的恶性肿瘤，近年来发病率逐年上升。根据国家癌症中心数据显示，甲状腺癌发病率已居于恶性肿瘤发病率的第7位[1]。甲状腺癌主要包括乳头状癌、滤泡状癌、髓样癌及未分化癌4种类型，其中，甲状腺乳头状癌（papillary thyroid carcinoma, PTC）的发生率在甲状腺癌的病理类型中居于首位。在众多甲状腺癌相关的基因中，BRAF基因突变是甲状腺乳头状癌最常见的突变位点，BRAFV600E突变率在甲状腺微小乳头状癌（papillary thyroid ...
吴宪吉 +5 more
doaj
Zhongguo shiyan zhenduanxue, 2013 慢性淋巴细胞性甲状腺炎（chronic lymphocyt-ic thyroiditis,CTL）又称桥本甲状腺炎（HT）,是以甲状腺淋巴细胞浸润为病理特征的自身免疫性炎症,是甲状腺炎中最常见的疾病,常见于中年女性,近年来发病率呈上升趋势。据文献报道,Dailay首先提出甲状腺癌可由HT恶变而来[1]。Pollock也认为HT属癌前病变[2]。此外,HT常常与其它甲状腺疾病并存,如甲状腺癌、腺瘤 ...
葛冠男 +4 more
doaj
Mechanisms of drug resistance to targeted drugs in thyroid cancer [PDF]
For well-differentiated and early-stage thyroid cancer， conventional treatment options such as surgery， thyroid-stimulating hormone suppression therapy， and radioactive iodine therapy can usually significantly extend patients’ overall survival and ...
WEN Xinyun, WU Juekun
core +1 more source
China Anti-Cancer Association guideline for diagnosis and treatment of neuroendocrine neoplasms (2025 edition) [PDF]
Neuroendocrine neoplasms (NENs) are a rare group of tumors that originated from peptidergic neurons and neuroendocrine cells, which has neuroendocrine differentiation characteristics and expresses neuroendocrine markers.
Society of Neuroendocrine Neoplasm of China Anti-Cancer Association
core +1 more source
Zhongguo shiyan zhenduanxue原发性甲状腺鳞状细胞癌（Primary squamous cell carcinoma of the thyroid, PSCCT）,是一种特殊类型的甲状腺恶性肿瘤，其恶性度极高，预后极差，其发病率仅占原发性甲状腺恶性肿瘤的0.2%～1.1%[1]。首诊时患者约60%表现为颈部肿物，约20%表现为呼吸困难或者吞咽困难，约15%表现为声音改变[2]。
赵雪, 张莹莹, 李彤, 赵静
doaj
Zhongguo shiyan zhenduanxue, 2013 目的探讨甲状腺乳头状癌颈部淋巴结转移规律及影响因素,为淋巴结清扫指征及范围的选择提供参考依据。方法回顾分析我院2008年6月至2011年12月初次治疗的1667例甲状腺乳头状癌患者的临床信息及病理资料,总结颈部淋巴结转移规律及影响因素。结果性别、年龄、肿瘤数目、肿瘤大小、局部浸润对甲状腺乳头状癌颈部淋巴结转移具有重要影响,转移在男性、低龄、多灶、肿瘤直径较大及局部浸润的患者中较为多见。结论甲状腺乳头状癌在制定淋巴结清扫指证及范围时,除重视术前影像学检查及术中触诊外,应充分评估影响淋巴结转移的高危因素 ...
李世杰 +6 more
doaj
Zhongguo shiyan zhenduanxue, 2017 桥本甲状腺炎（HT）,又称慢性淋巴细胞性甲状腺炎（CLT）,是一种器官特异性自身免疫性疾病,其主要特点是特异性甲状腺自身抗体形成和甲状腺内大量淋巴细胞浸润,最终导致甲状腺组织结构破坏和甲状腺功能低下。甲状腺癌（TC）是内分泌系统最常见的恶性肿瘤,病理分型分为甲状腺乳头状癌,甲状腺髓样癌,甲状腺滤泡状癌,甲状腺未分化癌,其中甲状腺乳头状癌（PTC）是TC中最常见的病理分型,约占70%-80%。HT和PTC作为最常见的甲状腺疾病之一,发病率均呈现上升趋势 ...
雒毅强, 张广
doaj