Results 1 to 10 of about 7,467 (211)
SARS‐CoV‐2 infection as cause of in‐utero fetal death: regional multicenter cohort study
Ultrasound in Obstetrics &Gynecology, Volume 62, Issue 6, Page 867-874, December 2023., 2023 ABSTRACT Objective Placental infection with severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) can lead to placental insufficiency and in‐utero fetal death (IUFD). The objective of this study was to confirm and quantify the extent to which fetoplacental infection with SARS‐CoV‐2 is a cause of fetal death.
M. Nkobetchou +9 more
wiley +1 more source
Ultrasound in Obstetrics &Gynecology, Volume 60, Issue 4, Page 487-493, October 2022., 2022 ABSTRACT Objective To investigate the diagnostic yield of clinical whole‐genome sequencing (WGS) in prenatally diagnosed non‐immune hydrops fetalis (NIHF). Methods This was a retrospective study of 23 fetuses with prenatally diagnosed NIHF, negative for trisomies and copy‐number variants, referred for analysis by WGS with an in‐silico panel of 281 ...
E. Westenius +4 more
wiley +1 more source
Ultrasound in Obstetrics &Gynecology, Volume 59, Issue 6, Page 715-722, June 2022., 2022 ABSTRACT Objective To determine the diagnostic yield of exome sequencing (ES) above that of chromosomal microarray analysis (CMA) or karyotyping in fetuses with multisystem structural anomalies (at least two major anomalies in different anatomical systems). Method This was a systematic review conducted in accordance with PRISMA guidelines.
M. Pauta +2 more
wiley +1 more source
Brachycephaly in French bulldogs and pugs is associated with narrow ear canals
Veterinary Dermatology, Volume 33, Issue 3, Page 214-e60, June 2022., 2022 Background Brachycephalic dog breeds have multiple skull malformations which may lead to anatomical changes in the external auditory canal. It is our frequent observation that in the otoscopic examination of the external ear in these breeds we are unable to visualise the tympanic membrane as a consequence of extreme narrowing of the proximal ear canal.
Tanja Töpfer +3 more
wiley +1 more source
Jianzhu Gangjiegou Jinzhan, 2023 为研究钢桁腹-混凝土组合箱梁的畸变效应，根据其结构特性和力学特性，考虑共同工作区对组合箱梁腹杆纵向刚度的贡献，提出一种更适用于该类组合箱梁的畸变扇性坐标分布模式。采用新畸变中心定义符合钢桁腹-混凝土组合箱梁畸变变形特征的畸变角，应用能量变分法建立畸变控制微分方程，并给出包含Krylov函数的初参数解。结合数值算例，分析钢桁腹-混凝土组合箱梁在均布畸变荷载作用下的畸变翘曲正应力，并通过有限元软件ANSYS验证所推导理论的正确性。通过改变腹杆壁厚、俯角等关键参数，探究其对畸变内力的影响规律。结果表明 ...
李永鹏, 丁南宏, 冀伟
doaj
UVA Assisted 4-Thiothymidine for Cancer Treatment [PDF]
, 2016 This article reviews the developments of 4-thiothymidine analogues, assisted with UVA light, as a novel cancer therapy. First, the key points on synthetic chemistry, photochemistry and cellular toxicity of 4-thiothymidine are summarized.
Feng, Luo +3 more
core +1 more source
Jianzhu Gangjiegou Jinzhan, 2023 为分析钢底板波形钢腹板梯形组合箱梁的畸变效应，利用圣维南原理考虑顶底板对波形钢腹板的约束作用，将组合箱梁等效为钢箱梁的过程中保持面内外抗弯刚度不变，基于板元框架法建立畸变控制微分方程并导出克雷洛夫函数形式的通解。结合数值算例的对比分析验证所提方法的合理性，并研究腹板俯角和梁高变化对畸变双力矩的影响。结果表明：相较于完全忽略腹板的面内抗弯刚度，考虑顶底板对腹板的约束作用更合理；波形钢腹板和钢底板对箱梁的畸变翘曲刚度和横向框架刚度均有较大程度的削弱 ...
陈东亮, 张元海, 刘泽翔
doaj
Gaoya dianqi, 2022 金属化膜电容器因其自愈特性可在高电场强度下工作，但电极边缘的电场畸变导致的电极退化会使电容量下降，对电极边缘处的电场畸变程度的评估可为电容器的结构设计提供支撑。文中基于三结合点附近电场分布特点，提出了一种评估电极边缘电场畸变程度的新方法，以T型金属化膜电容器为计算模型，对有限元得到的电极附近电场的数值解，采用电场分布的理论解析式进行拟合，拟合优度在99%以上，定义拟合系数为电场畸变系数来评估电场畸变程度，并得到电极厚度、薄膜厚度和分割间隙对电场畸变程度的影响规律 ...
王佳昕 +4 more
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Zhongguo shiyan zhenduanxue, 2023 卵巢畸胎瘤以成熟性畸胎瘤较为多见，成熟性畸胎瘤恶变本身少见，常见恶变类型为鳞癌，其次为腺癌，恶变为黑色素瘤则更少见，其发生率为0.2%～0.8%[1]。卵巢畸胎瘤内的皮肤、脑膜、视网膜及幼稚神经脊等可含有正常卵巢组织中不存在的黑色素母细胞，故大多数卵巢黑色素瘤来源于成熟畸胎瘤的恶变[2]。我们收治1例卵巢恶性黑色素瘤合并成熟性囊性畸胎瘤患者，临床特征及诊治情况报道如下。
杨萌, 纪诚, 刘俊宝
doaj
Developmental Medicine &Child Neurology, Volume 61, Issue 3, Page E1-E35, March 2019., 2019 目的 本国际临床指南由欧洲残疾儿童学会（the European Academy of Childhood Disability，EACD）牵头制定，旨在解决发育性协调障碍（developmental coordination disorder，DCD）的定义、诊断、评估、干预以及与社会心理方面的临床应用关键问题。 方法 本指南针对五个领域的关键问题，通过文献综述和专家团队的正式讨论达成共识。为保证指南的循证基础，以“机制”、“评估”和“干预”为检索词, 对2012年更新以来提出的最新建议以及新增的“社会心理问题”和“青少年/成人”为检索词进行检索。根据牛津大学循证医学中心证据等级 (证据水平 [level of evidence, LOE]1–4) 将结果进行分类，最终转化为指南建议。并由国际 ...
Jing Hua +6 more
wiley +1 more source