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含泊马度胺全口服方案二线治疗多发性骨髓瘤的疗效与安全性分析

Zhongshan Daxue xuebao. Yixue kexue ban
目的评价含泊马度胺全口服治疗方案二线治疗多发性骨髓瘤的疗效与安全性。方法回顾性分析2020年3月至2023年12月在我中心接受含泊马度胺全口服方案作为二线治疗的多发性骨髓瘤患者共22例，评价其疗效与安全性。结果22例患中位年龄为71.5岁，含泊马度胺的全口服二线治疗方案包括IPD 7例，PCD 11例， XPD 2例，PD 2例，中位治疗周期数为14，二线治疗ORR为63.64%，VGPR以上疗效为 36.36%。有来那度胺暴露史的13例患者中，ORR为53.85%， VGPR以上疗效为23.08 ...
肖洁, 王秀菊, 谢双锋, 李益清, 张国扬, 杨文娟, 刘红云, 聂大年   +7 more
doaj  

[Analysis of treatment response and post-discontinuation efficacy maintenance of cyclophosphamide monotherapy in T-cell large granular lymphocytic leukemia]. [PDF]

Zhonghua Xue Ye Xue Za Zhi
Zhang LL, Tian LZ, Pan H, Gao Z, Li WW, Li RN, Zhao JY, Huang JB, Zhao X, Li JP, Nie N, Yu X, Li LY, Kuang ZX, Fang LW, Shi J.   +15 more
europepmc   +1 more source

[Effectiveness of orthopedic surgery for 247 patients with moderate and severe hallux valgus]. [PDF]

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi
Zhang G, Yao J, Li W, Zhang L, Han Q, Rong C, Wei B, Zhang L.   +7 more
europepmc   +1 more source

[Efficacy of free lateral arm tissue flap in repairing complex finger wounds]. [PDF]

Zhonghua Shao Shang Yu Chuang Mian Xiu Fu Za Zhi
Yang X, Liu WH, Duan JZ, Fang X, Xu YQ, Shi Y, Zhang X, He XQ.   +7 more
europepmc   +1 more source

[Effectiveness of arthroscopic treatment for femoroacetabular impingement syndrome combined with ligamentum teres injury]. [PDF]

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi
Han S, Li S, Jia D, Li Y, Cai G.
europepmc   +1 more source

[Clinical Analysis of Supral-abyrinthine Cholesteatoma and Literature Review]. [PDF]

Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
Qian W, Chen C, Zhang Q, Wang C, Gao Y, Yu S, Yang H, Li G, Li J.   +8 more
europepmc   +1 more source

[Efficacy of β-Blockers in Older Adults With Hypertension Combined With Vascular Dementia]. [PDF]

Sichuan Da Xue Xue Bao Yi Xue Ban
Tian Z, Li W, Tian W, Li H, Xue X, Zhao N.   +5 more
europepmc   +1 more source

[Machine Learning-Assisted Efficacy Evaluation of Resveratrol Therapy in a Mouse Model of Acute Pancreatitis]. [PDF]

Sichuan Da Xue Xue Bao Yi Xue Ban
Li Z, Tian Y, Cai W, Wu Y, Liu S, Yao L, Li Y, Wu X, Liu T, Huang W.   +9 more
europepmc   +1 more source

[Effectiveness of three-dimensional printing-assisted vascularized fibular graft for repairing metatarsal defects]. [PDF]

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi
Zhou R, Ju J, Yang L, Guo L, Liu Y, Geng C, Liu Z, Niu Z, Dong S.   +8 more
europepmc   +1 more source

[Effectiveness of staged therapy using external fixation frame for infectious nonunion near knee joint]. [PDF]

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi
Wang Z, Guo X, Kang Z, Wang X, Jin G, Tan H, Deng X, Feng W.   +7 more
europepmc   +1 more source