Linchuang shenzangbing zazhi, 2013 目的 观察恩替卡韦联合糖皮质激素治疗乙型肝炎(乙肝)病毒相关性肾炎的临床效果。方法 选取在我完住院的乙肝病毒相关性肾炎患者65例,将患者随机分成2组。单一抗病毒组30例,单用恩替卡韦抗病毒治疗。联合治疗组35例,恩替卡韦抗病毒联合适量、短期糖皮质激素治疗。2组均给予常规护肝、降酶及保护肾功能治疗。对所有患者治疗前、后乙肝病毒DNA、肝功能、肾功能、血尿常规进行测定。结果 在抗病毒、护肝方面,治疗12个月后,2组血清乙肝病毒DNA载量及丙氨酸氨基转移酶、天冬氨酸氨基转移酶水平下降幅度均无明显差异 ...
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小剂量泼尼松联合恩替卡韦治疗以大量蛋白尿表现的乙肝病毒相关性肾炎3例 附视频
Linchuang shenzangbing zazhi乙肝病毒相关性肾炎（hepatitisBvirus-associated glomerular nephritis,HBV-GN）是指由乙型肝炎病毒（hepatitis B virus,HBV）直接或间接诱发的肾小球肾炎，中国是乙型肝炎的高发国家。据数据统计，中国成年人HBV携带率高达10%以上，其中HBV-GN的发生率约为9.0%[1]。针对HBV-GN目前临床尚无特效疗法，单纯核苷酸类似物治疗大量蛋白尿HBV-GN的尿蛋白缓解率低[2]，临床疗效并不理想。目前通过糖皮质激素 ...
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