Results 1 to 10 of about 948 (69)

伴有PAXIP1和NOS3基因突变的额颞叶痴呆1例

open access: yesZhongguo shiyan zhenduanxue, 2021
额颞叶痴呆(FTD)是一组以进行性额颞叶变性(FTLD)为共同病理特征的临床综合征,发病率每年约为1.6-4.1/10万,性别无差异。在65岁以下人群中,FTD是仅次于阿尔茨海默病的第二常见痴呆。FTD是一种异质性疾病,存在不同的临床表型及神经病理类型,临床上往往以明显的人格、行为改变和语言障碍为特征,可以合并运动神经元病[1]。
王瑞, 张雷, 赵修琦, 南善姬
doaj  

MFDC-Net: A breast cancer pathological image classification algorithm incorporating multi-scale feature fusion and attention mechanism(MFDC-Net:一种融合多尺度特征和注意力机制的乳腺癌病理图像分类算法)

open access: yesZhejiang Daxue xuebao. Lixue ban, 2023
乳腺癌是全球最常见的恶性肿瘤之一,采用传统方法诊断需花费大量时间和精力,且受个人能力影响较大。用计算机辅助诊断的方法,可以提高病理图像分类的准确率和效率,从而满足临床应用的需求。为此,提出一种基于DenseNet的融合多尺度特征和注意力机制的乳腺癌病理图像分类算法(MFDC-Net)。在密集块中引入坐标注意力机制,精准定位重要特征的空间信息。采用多尺度池化过渡层,通过不同卷积核的平均池化和普通卷积,在实现降维的同时扩大感受野。采用多尺度特征增强模块,融合深层次图像特征,提高分类性能。结果显示,MFDC ...
方于华(FANG Yuhua)   +1 more
doaj   +1 more source

移植肾脏病临床特点与病理类型的相关性分析

open access: yesZhongguo shiyan zhenduanxue, 2021
目的探讨移植肾脏病临床特点及与病理类型相关性,为移植肾脏病的个体化治疗及评估预后提供依据。方法回顾性分析332例移植肾脏病患者病例资料,总结临床特点,依据Banff2007标准进行病理诊断及分类,并分析临床特点与病理类型的相关性。结果移植肾脏病临床表现为无尿或少尿、血尿、蛋白尿、水肿、高血压、移植肾肿胀疼痛、肾功能异常等;临床症候群分布为无尿或少尿型6.02%、隐匿性肾炎型9.04%、肾炎综合征型17.17%、肾病综合征型22.89%、肾功能不全型44.88%;肾移植围术期移植肾病理表现为超急性排斥反应、
王锁刚   +5 more
doaj  

ABCA12 Frameshift Deletion in Domestic Cats With Ichthyosis Fetalis

open access: yesVeterinary Dermatology, Volume 37, Issue 3, Page 365-374, June 2026.
ABSTRACT Background Ichthyosis fetalis (IF), also known as harlequin ichthyosis, is a rare and often fatal autosomal recessive congenital skin disorder. It is characterized by thickened, hard skin plaques and deep skin fissures that limit mobility and cause malformations of the eyes, lips and ears.
Jeanna M. Blake   +2 more
wiley   +1 more source

A Novel Topical Emollient Plus for Canine Atopic Dermatitis: A Clinical Trial Assessing Efficacy and User Acceptance

open access: yesVeterinary Dermatology, Volume 37, Issue 2, Page 293-305, April 2026.
Background: Canine atopic dermatitis (cAD) is a common, chronic skin condition characterised by epidermal barrier dysfunction, immune dysregulation and cutaneous dysbiosis. While “emollient plus” formulations are widely used in human atopic dermatitis, their role in cAD remains underexplored. Hypothesis/Objectives: To evaluate the clinical efficacy and
Beatriz Fernandes   +8 more
wiley   +1 more source

Fetoscopic laser ablation vs standard management for Type‐II and Type‐III vasa previa

open access: yesUltrasound in Obstetrics &Gynecology, Volume 67, Issue 3, Page 320-328, March 2026.
ABSTRACT Objective The standard management (SM) for vasa previa (VP) includes antepartum inpatient admission at 28–32 weeks' gestation followed by Cesarean delivery at 34–37 weeks. Case reports and case series have reported on fetoscopic laser ablation (FLA) as an alternative management approach for Types‐II and ‐III VP.
S. Backley   +11 more
wiley   +1 more source

Conservation Status, Decline Factors, and Strategies for Globally Endangered Musk Deer (Moschus spp.) in China 中国境内全球濒危麝属 (Moschus spp.) 物种的保护现状、致危因素及应对策略

open access: yesWildlife Letters, Volume 4, Issue 1, Page 42-55, March 2026.
This review summarizes the status of musk deer in China, highlighting severe population declines due to illegal hunting and habitat loss, and proposes integrated conservation strategies including habitat protection, captive breeding, and law enforcement to support the recovery and sustainable management of this ecologically and economically important ...
Feng Jiang   +8 more
wiley   +1 more source

The role of child language ability and parental mentalization in early child dysregulation

open access: yesInfant Mental Health Journal: Infancy and Early Childhood, Volume 47, Issue 1, January 2026.
Abstract Dysregulation in early childhood is associated with increased vulnerability to psychopathology and poor psychosocial outcomes. While there is evidence that both child language ability and parental mentalization are associated with dysregulation in early childhood, there is little understanding of the relationships between these variables, and ...
Sara Cibralic   +6 more
wiley   +1 more source

Endometrial assessment in abnormal uterine bleeding: transvaginal ultrasound alone may not be good enough

open access: yesUltrasound in Obstetrics &Gynecology, Volume 67, Issue 1, Page 79-88, January 2026.
ABSTRACT Objective To evaluate the proportion of optimal assessments of endometrial thickness (ET) achieved by transvaginal ultrasound (TVS) compared with a multimodal (MM) sonographic approach in women with abnormal uterine bleeding (AUB). Methods This prospective observational study was a subset of the EPI‐SURE study conducted between June and ...
S. Nijjar   +5 more
wiley   +1 more source

外毛根鞘癌14例临床病理分析

open access: yesZhongshan Daxue xuebao. Yixue kexue ban, 2013
【目的】 探讨外毛根鞘癌的临床病理特点和与其他皮肤恶性肿瘤的鉴别诊断要点?【方法】 收集确诊的外毛根鞘癌14例,整理一般临床资料,系统观察大体标本和镜下病理形态学特征?【结果】 14例外毛根鞘癌发病年龄22 ~ 72岁(平均年龄45.5岁),男女比例4:10,发病部位均位于头颈部?大体上绝大部分为孤立性?分叶状?较大的外生性团块,仅1例为囊性肿物;镜下见癌细胞胞浆丰富?嗜酸性或透亮?无细胞间桥,具有不伴颗粒层的突然角化等病理形态学特征?【结论】 外毛根鞘癌具有独特的临床病理特征 ...
朱重梅
doaj  

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