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联合超声影像组学和临床特征构建列线图模型预测甲状腺乳头状癌病理侵袭性 [PDF]
浙江大学学报. 医学版目的联合超声影像组学特征和临床特征构建列线图模型，并评估其对甲状腺乳头状癌（PTC）病理侵袭性的预测价值。方法纳入2024年1月至2025年5月在浙江省人民医院诊断为PTC的224例患者，收集相关基线数据、实验室检查数据及超声原始图像。将患者按8∶2随机分为训练队列（n=179）和测试队列（n=45）。同时收集浙江省人民医院2025年6—11月诊断为PTC的42例患者作为独立验证队列。将PTC结节存在包膜外侵犯、脉管浸润、神经侵犯、腺内播散、腺外侵犯 ...
刘 晗 +5 more
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Zhongguo shiyan zhenduanxue, 2021 额颞叶痴呆（FTD）是一组以进行性额颞叶变性（FTLD）为共同病理特征的临床综合征,发病率每年约为1.6-4.1/10万,性别无差异。在65岁以下人群中,FTD是仅次于阿尔茨海默病的第二常见痴呆。FTD是一种异质性疾病,存在不同的临床表型及神经病理类型,临床上往往以明显的人格、行为改变和语言障碍为特征,可以合并运动神经元病[1]。
王瑞, 张雷, 赵修琦, 南善姬
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Zhejiang Daxue xuebao. Lixue ban, 2023 乳腺癌是全球最常见的恶性肿瘤之一，采用传统方法诊断需花费大量时间和精力，且受个人能力影响较大。用计算机辅助诊断的方法，可以提高病理图像分类的准确率和效率，从而满足临床应用的需求。为此，提出一种基于DenseNet的融合多尺度特征和注意力机制的乳腺癌病理图像分类算法（MFDC-Net）。在密集块中引入坐标注意力机制，精准定位重要特征的空间信息。采用多尺度池化过渡层，通过不同卷积核的平均池化和普通卷积，在实现降维的同时扩大感受野。采用多尺度特征增强模块，融合深层次图像特征，提高分类性能。结果显示，MFDC ...
方于华(FANG Yuhua) +1 more
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Zhongguo shiyan zhenduanxue, 2021 目的探讨移植肾脏病临床特点及与病理类型相关性,为移植肾脏病的个体化治疗及评估预后提供依据。方法回顾性分析332例移植肾脏病患者病例资料,总结临床特点,依据Banff2007标准进行病理诊断及分类,并分析临床特点与病理类型的相关性。结果移植肾脏病临床表现为无尿或少尿、血尿、蛋白尿、水肿、高血压、移植肾肿胀疼痛、肾功能异常等;临床症候群分布为无尿或少尿型6.02%、隐匿性肾炎型9.04%、肾炎综合征型17.17%、肾病综合征型22.89%、肾功能不全型44.88%;肾移植围术期移植肾病理表现为超急性排斥反应、
王锁刚 +5 more
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Rare Metals, Volume 45, Issue 8, August 2026.ABSTRACT Due to their exceptional porosity, structural versatility, and modular coordination chemistry, metal–organic frameworks (MOFs) have emerged as versatile platforms for targeted drug delivery. These structures enable fine‐tuning of pore size, surface activity, and framework stability for the encapsulation of a broad range of therapeutics ...
Rui Hua +9 more
wiley +1 more source
Rare Metals, Volume 45, Issue 8, August 2026.ABSTRACT Advanced metallic glasses, leveraging their ultrahigh strength, excellent corrosion resistance, superior soft magnetic properties and good biocompatibility, have gradually become indispensable strategic cornerstones in critical fields such as aerospace, electronic information and energy power. This unique combination of properties enables them
Yizhou Liu +11 more
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Ultrasound in Obstetrics &Gynecology, Volume 68, Issue 2, Page 256-269, August 2026.ABSTRACT Objectives The primary aims of this study were to validate externally the diagnostic performance of the Assessment of Different NEoplasias in the adneXa (ADNEX) model for distinguishing between malignant and benign adnexal masses, when used by non‐expert ultrasound examiners in general gynecological settings with a low prevalence of ovarian ...
I. M. Dueholm Hjorth +11 more
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Ultrasound in Obstetrics &Gynecology, Volume 68, Issue 1, Page 88-98, July 2026.ABSTRACT Objective To identify prenatal predictors of tuberous sclerosis complex (TSC) in fetuses with one or more cardiac rhabdomyomas (CR), evaluate an integrated multimodal diagnostic workflow using fetal magnetic resonance imaging (MRI) and trio whole‐exome sequencing (trio‐WES) and characterize perinatal outcomes.
X. Cai +8 more
wiley +1 more source
Ultrasound in Obstetrics &Gynecology, Volume 67, Issue 6, Page 806-814, June 2026.ABSTRACT Objective To investigate the incidence of pre‐eclampsia (PE) and the predictive performance of the Fetal Medicine Foundation (FMF) first‐trimester PE screening algorithm across pregnancies conceived using assisted reproductive technology (ART), after ovulation induction (OI) and through spontaneous conception (SC).
A. S. L. Kjaer +23 more
wiley +1 more source
Zhongshan Daxue xuebao. Yixue kexue ban, 2013 【目的】 探讨外毛根鞘癌的临床病理特点和与其他皮肤恶性肿瘤的鉴别诊断要点?【方法】 收集确诊的外毛根鞘癌14例,整理一般临床资料,系统观察大体标本和镜下病理形态学特征?【结果】 14例外毛根鞘癌发病年龄22 ~ 72岁(平均年龄45.5岁),男女比例4:10,发病部位均位于头颈部?大体上绝大部分为孤立性?分叶状?较大的外生性团块,仅1例为囊性肿物;镜下见癌细胞胞浆丰富?嗜酸性或透亮?无细胞间桥,具有不伴颗粒层的突然角化等病理形态学特征?【结论】 外毛根鞘癌具有独特的临床病理特征 ...
朱重梅
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