Results 11 to 20 of about 1,464 (128)
Infant Mental Health Journal: Infancy and Early Childhood, Volume 43, Issue 3, Page 455-473, May 2022., 2022 Abstract Research points to the significant impact of maternal distress on the parent‐infant relationship and infant development. The Newborn Behavioral Observations (NBO) is a brief intervention supporting the infant, the parent and their relationship.
Susan Nicolson +2 more
wiley +1 more source
Translocator protein activates autophagy in diabetic neuropathic pain rats via regulation of the Keap1/Nrf2/HO-1 signaling [PDF]
, 2023 Objective·To study the effects of translocator protein (TSPO) agonist Ro5-4864 on autophagy and Kelch-like ECH-associated protein 1 (Keap1)/nuclear factor erythroid-derived-2-like 2 (Nrf2)/heme oxygenase-1 (HO-1) signaling in diabetic neuropathic pain ...
GAO Nan +5 more
core +1 more source
Visual snow syndrome and migraine: a review
Eye, 2023 视雪综合征是一种神经系统疾病, 特征为持续性的在整个视野中移动的小点, 通常与复杂的视觉症状有关。这些症状可能以视觉残像、内视现象、夜盲症和光敏感的形式表现。尽管部分症状可能是良性的, 但它们仍然可能会对经历过这些症状的人造成重大影响, 尤其是在突然发作的情况下。 随着视雪综合征在临床实践中越来越多被认识和鉴别, 我们开始了解其典型的表现和潜在的病理生理学。然而, 视雪综合征的治疗仍然具有相当大的挑战性, 需要聚焦于阐明该综合征的生物学机制。这也是目前视雪综合征研究的主要方向, 主要涉及神经影像学 ...
E. Silva, F. Puledda
semanticscholar +1 more source
Effect of Sleep Time and Sleep Quality on the Risk of Low Back Pain among the Middle-aged and Elderly People in China [PDF]
, 2022 BackgroundAs one of the disabling pains, low back pain seriously affects the quality of life of patients and causes a huge economic burden to them. Studies have shown that poor sleep quality has a certain effect on the occurrence of low back pain, but ...
LI Qiaomei, WANG Yihui, YU Li, WANG Pengju, GAO Yinyan, ZHAO Honglin, DING Guowu
core +1 more source
小鼠岛叶皮质5型代谢型谷氨酸受体对神经病理性疼痛的调控作用 [PDF]
, 2018 目的:通过保留性神经损伤(SNI)模型,探索神经病理性疼痛发生后,岛叶皮质(IC)中FOS蛋白和5型代谢型谷氨酸受体(m Glu R5)及其下游分子的表达变化,并观察对岛叶皮质局部应用m Glu R5激动剂DHPG和拮抗剂MPEP对动物疼痛行为的影响。方法:将健康成年的雄性C57BL/6小鼠随机分为SNI组和假手术组(Sham组),SNI组采用SNI模型制造神经病理性疼痛模型。造模后通过机械痛行为学检测造模是否成功,通过免疫荧光染色检测岛叶皮质FOS蛋白的表达变化,通过Western ...
侯立朝 +4 more
core +1 more source
背根神经节 STAT3/CCL2 信号通路在泰素诱导慢性疼痛中的作用 [PDF]
, 2020 【目的】研究转录因子STAT3通过上调背根神经节趋化因子CCL2的表达介导泰素诱导慢性疼痛的机制。【方法】66只大鼠随机分成6组，包括：溶剂对照组（V）、泰素组（T）、鞘内注射CCL2中和性抗体+泰素组（A+T）、鞘内注射S3I-201+泰素组（S+T）、泰素+溶剂组（T+R）、鞘内注射C188-9+泰素组（C+T）。连续5d腹腔注射化疗药泰素，建立慢性疼痛模型。采用蛋白印迹法、RT-qPCR方法和免疫组织化学方法，确定STAT3、CCL2在背根神经节表达的变化和细胞类型。鞘内注射CCL2中和性抗体 ...
唐名杰, 廖维勇, 王勇, 黄文君
core
CSF-1 自背根节向脊髓转运对长春新碱诱导神经病理性痛大鼠小胶质细胞活化及其炎症的影响 [PDF]
, 2020 【目的】探讨 CSF-1 自背根节向脊髓转运对长春新碱诱导神经病理性痛大鼠小胶质细胞活化的影响。【方法】鞘内置管成功雄性SD 大鼠54 只，体质量200～230 g，10～12 周龄，采用随机数字表法分为3 组（每组 18 只）：对照组（Control）、化疗诱发神经病理痛+鞘内注射正常 IgG 组（CINP）、化疗诱发神经病理痛+鞘内注射CSF1 中和抗体（CINP+anti）。隔日腹腔注射长春新碱 125 μg/kg（共计 4 次）建立 CINP 动物模型。分别采用机械缩足反射阈值（MWT ...
付宝军 +4 more
core
Zhongshan Daxue xuebao. Yixue kexue ban, 2023 目的探讨睡眠相关性痛性勃起（SRPE）患者夜间阴茎勃起功能和正常男性之间的差异。方法从2019年7月1起至2022年12月15日，对来我院泌尿男科就诊的29例SRPE患者（实验组）及58例志愿者（对照组）进行临床对照研究。通过Rigiscan分别监测两组受试者监测当晚总的睡眠监测时间、夜间勃起次数及在阴茎勃起达到60% ~ 79%和80%~100%时勃起平均硬度、持续时间、平均周径增长；嘱咐患者与志愿者觉醒时自行作书面记录醒来的时间及次数，然后结合勃起监测数据 ...
胡海兵 +5 more
doaj
Veterinary Dermatology, Volume 35, Issue 2, Page 197-206, April 2024.Background – Erythemato‐ceruminous otitis externa (ECOE) is frequently seen in dogs affected with an allergic skin disease, with recurrent secondary bacteria and yeast overgrowths (detected on cytological examination). Objectives – The objective of the study was to compare the efficacy and safety of an ear spray containing only hydrocortisone aceponate
Delphine Rigaut +3 more
wiley +1 more source
Surgical treatment of neuropathic pain [PDF]
, 2013 Neuropathic pain (NP) is a transient dysfunction caused by the damage of peripheral nerve and central nervous system, characterized with hyperalgesia, allodynia and spontaneous pain.
Zhi-pei LING, Zhi-qiang CUI
core +1 more source