Neurnal mechanisms underlying the divergent effect of depression on pain
, 2013 临床实践与基础研究表明，抑郁对诱发痛和自发痛的影响存在分离效应，即抑郁能够减弱诱发痛而增强自发痛，然而，这种分离效应的神经机制目前尚不清楚。本人在站期间的研究采用不确定预期的慢性温和应激模型作为抑郁动物模型，通过清醒动物电生理技术以及行为药理学等技术，探索抑郁对诱发痛和自发痛存在分离效应的成因，并试图阐明抑郁影响疼痛的神经机制。 主要发现如下: ( 1)通过对抑郁状态下所记录到的大鼠内外侧疼痛通路对诱发痛和自发痛的神经活动进行分析发现，给予大鼠自发痛时，抑郁组大鼠内侧和外侧通路的神经元活动都显著增加，
王宁
core
Effect of prior experience on pain perception in rats
, 2011 先前的疼痛经验可能是影响将来疼痛相关心理疾患重要的因素。过去的动物研究表明幼年期疼痛体验对成年后伤害性反应的影响，但是在成年之后获得的疼痛经验与动物将来的痛觉感知之间的关系仍不清楚。我们研究先前慢性炎症痛经验对以后的福尔马林自发痛和疼痛暗示诱发的预期性反应的影响。并考察了与疼痛无关的慢性应激对大鼠痛行为的影响。最后通过多通道记录技术，在健康大鼠上考察再次伤害性刺激对疼痛暗示诱发中枢神经元放电活动的改变，以初步了解疼痛经验对中枢痛觉信息编码的调节机制。 主要结果： 1.
李胜光
core
[Research progress on the causes of pain in knee osteoarthritis]. [PDF]
Zhongguo Xiu Fu Chong Jian Wai Ke Za ZhiWei N, Zheng Z.
europepmc +1 more source
[A compulsory course in clinical treatment of burn patients: pain and analgesia]. [PDF]
Zhonghua Shao Shang Yu Chuang Mian Xiu Fu Za ZhiNie FF.
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[Temporal changes of chronic postsurgical pain in mice: the regulatory role of CX3CL1 in the dorsal root ganglion]. [PDF]
Nan Fang Yi Ke Da Xue Xue BaoZhao B +8 more
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[Clinical application of dynamic visual acuity testing in patients with vestibular migraine]. [PDF]
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za ZhiShi H +8 more
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[Mechanisms of spinal microglia and astrocytes in exercise-induced analgesia]. [PDF]
Zhong Nan Da Xue Xue Bao Yi Xue BanHu S, You H, Lei J.
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[Study on occurrence of anterior ankle pain after distal tibial extra-articular fractures treated with retrograde tibial intramedullary nail]. [PDF]
Zhongguo Xiu Fu Chong Jian Wai Ke Za ZhiXiong Y +5 more
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[A qualitative study of sensory hypersensitivity in children with autism spectrum disorder and individuals with subclinical autistic traits]. [PDF]
Zhongguo Dang Dai Er Ke Za ZhiLiu YC, Zhu DL, Hong XR, Zhou HY.
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[The role and mechanism of chemokine network in promoting osteoarthritis progression by regulating synovial macrophage heterogeneity]. [PDF]
Zhongguo Xiu Fu Chong Jian Wai Ke Za ZhiLin Y, Wu L, Chen Q, Shen B.
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