Effect of prior experience on pain perception in rats
, 2011 先前的疼痛经验可能是影响将来疼痛相关心理疾患重要的因素。过去的动物研究表明幼年期疼痛体验对成年后伤害性反应的影响，但是在成年之后获得的疼痛经验与动物将来的痛觉感知之间的关系仍不清楚。我们研究先前慢性炎症痛经验对以后的福尔马林自发痛和疼痛暗示诱发的预期性反应的影响。并考察了与疼痛无关的慢性应激对大鼠痛行为的影响。最后通过多通道记录技术，在健康大鼠上考察再次伤害性刺激对疼痛暗示诱发中枢神经元放电活动的改变，以初步了解疼痛经验对中枢痛觉信息编码的调节机制。 主要结果： 1.
李胜光
core
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