Huli yanjiu, 1999 异体胰肾联合移植术后,由于病人服用大量的免疫抑制剂,易出现感染,除口服或静脉给予大剂量的抗生素外,护理也至关重要。1 病例介绍病人,男,53岁。12ａ前出现多饮、多食、多尿、消瘦等症状,门诊以“糖尿病”治疗。4ａ前,又出现少尿、下肢水肿,在其它医院行肾穿刺活检,报告...
doaj
[Reoxygenation improves reduced hypothalamic leptin responsiveness induced by intermittent hypoxia in obese rats]. [PDF]
Nan Fang Yi Ke Da Xue Xue BaoDong M, Zhu T, Ma J, DU X, Feng Y.
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, 2014 已知腦缺血會導致腦細胞壞死，血腦屏障(BBB)結構之受損，及嗜中性白血球浸潤到腦組織引起發炎造成組織之二次傷害。近年來瘦素被發現具有保護神經細胞及腦組織對抗缺血性傷害之功能。本實驗室因此進一步針對其保護機制做探討，發現將瘦素注射於缺血鼠腦部可降低BBB通透性，減少受損腦組織中嗜中性白血球之數量，及減緩腦組織發炎水腫的程度。然而瘦素對BBB通透性的保護機轉及對嗜中性白血球浸潤的抑制機轉，目前並不清楚，本論文因此先針對瘦素對缺血內皮細胞(BBB的重要成員之一)不同活性之調控做探討 ...
Hsu, Pei-Chen, 許珮甄
core
[Exogenous leptin improves cerebral ischemia-reperfusion-induced glutamate excitotoxic injury in mice by up-regulating GLT-1 and GLAST expression in astrocytes]. [PDF]
Nan Fang Yi Ke Da Xue Xue BaoChen J +7 more
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[Survey on physical development and nutritional status of children aged 3-6 years in Urumqi City, 2018-2024]. [PDF]
Zhongguo Dang Dai Er Ke Za ZhiGuo YJ, Gao G, Zhao Z, Zhang DX.
europepmc +1 more source
[Impact of pre-pregnancy body mass index on maternal and infant outcomes in twin pregnancies]. [PDF]
Zhongguo Dang Dai Er Ke Za ZhiWang HY +24 more
europepmc +1 more source
Evaluation of the glioma growth and angiogenic effects of leptin in brain slice model
惡性神經膠細胞瘤(glioma)是神經系統原發極度惡性的腫瘤，復發率高，即使積極治療，對改善病人的存活時間及預後的程度仍非常有限，而目前所能使用於腦瘤的藥物極少，因此需發展新的治療標的。瘦體素(Leptin)是一種主要由脂肪組織所分泌的激素，近來發現，瘦體素具有促進細胞生長的作用，且瘦體素和其受體(ObR)在許多惡性腫瘤上過度表現，此可能與腫瘤細胞的生長及腫瘤的惡性程度具有密切的關係。本研究假設瘦體素刺激神經膠細胞瘤的生長及腫瘤血管生成，因此期望給予抑制劑可降低腫瘤生長及血管生成 ...
張家禎, Chia-Chen Chang
core
[Impact of overweight and obesity on quality of life and body image satisfaction in school-aged children and the mediating effects on academic performance]. [PDF]
Zhongguo Dang Dai Er Ke Za ZhiZhang ZY +7 more
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Genotyping of ESR, PRLR, RBP4 and LEP Genes Associated with Reproductive Traits of Black Pigs
, 2014 本試驗之目的為利用PCR-RFLP及微序列分析方法（minisequencing method）進行台灣黑毛豬之動情素接受體（estrogen receptor, ESR）、泌乳素接受體（prolactin receptor, PRLR）、維生素A結合蛋白質4 （retinol-binding protein 4, RBP4）及瘦體素（leptin, LEP）基因之基因型分析。先以PCR-RFLP之方法鑑定出ESR、PRLR、RBP4及LEP基因之基因型，再以微序列之方法分析 ...
Chen, Chia-Chi, 陳嘉琪
core
[Research progress on the microbiota-immune-metabolism axis in childhood obesity-related asthma]. [PDF]
Zhongguo Dang Dai Er Ke Za ZhiXiao SC, Zhang F.
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