目的探究雌性大鼠性早熟对糖代谢和脂代谢的影响。方法将60只两天龄的雌性大鼠随机分为性早熟组和正常组两组,分别在5天龄时给予达那唑(300 μg/只)或溶剂大豆油进行皮下注射,从21天龄起每天观察大鼠的阴道开口状况。建模成功的两组按照阴道开口顺序分别于阴道开口后3 d、7周龄和12周龄进行处死,处死前空腹12 h。方法测量麻醉后的体重和鼻肛长,通过酶联免疫吸附试验测量葡萄糖、胰岛素、血脂、雌二醇、瘦素和脂联素的浓度,病理切片观察肾周脂肪、子宫和卵巢的变化。结果通过正常组和早熟组两组3个时间点对比 ...
林小雅 +7 more
doaj
本研究对北京动物园1头非洲象交配、分娩、哺育等一系列繁殖行为进行了详细的观察和描述。分析表明影响非洲象繁殖的主要因素有:1)妊娠期间饲养环境内的噪音污染;2)分娩后圈内地面状况;3 )哺乳期的营养供应等。根据研究结果,为动物园非洲象的饲养繁殖提出了几点建议:1)妊娠期在圈内安装监控设备,减少人员走动;2)分娩后可在地面垫草,帮助幼兽尽早站立;3)哺乳期发现雌象消瘦属正常现象,不宜增加精料。
张耀华 +5 more
doaj
异体胰肾联合移植术后,由于病人服用大量的免疫抑制剂,易出现感染,除口服或静脉给予大剂量的抗生素外,护理也至关重要。1 病例介绍病人,男,53岁。12a前出现多饮、多食、多尿、消瘦等症状,门诊以“糖尿病”治疗。4a前,又出现少尿、下肢水肿,在其它医院行肾穿刺活检,报告...
doaj
[Reoxygenation improves reduced hypothalamic leptin responsiveness induced by intermittent hypoxia in obese rats]. [PDF]
Dong M, Zhu T, Ma J, DU X, Feng Y.
europepmc +1 more source
[Exogenous leptin improves cerebral ischemia-reperfusion-induced glutamate excitotoxic injury in mice by up-regulating GLT-1 and GLAST expression in astrocytes]. [PDF]
Chen J +7 more
europepmc +1 more source
[Construction of risk prediction models of hypothermia after transurethral holmium laser enucleation of the prostate based on three machine learning algorithms]. [PDF]
Jiang J, Feng S, Sun Y, An Y.
europepmc +1 more source
[Oral Health Status of Obese Children andIntervention Strategies]. [PDF]
Cheng R, Lei L, Zhang R, Cai H, Hu T.
europepmc +1 more source
[Research progress on clinical characteristics and pathological mechanisms of lean metabolic-associated fatty liver disease]. [PDF]
He N +5 more
europepmc +1 more source
[Association of Body Mass Index and Weight Gain With Obesity-Related Breast Cancer Risk Biomarkers in Adult Chinese Women]. [PDF]
Zhou M +6 more
europepmc +1 more source
[Aerobic exercise regulates macrophage polarization and improves insulin resistance in mice: the mediating role of miR-221-3p]. [PDF]
Li N, Zhang L, Guo Q, Zhou Y, Liu C.
europepmc +1 more source

