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Journal of Diabetes, Volume 13, Issue 12, Page 1007-1014, December 2021., 2021 Highlights This prospective study compares 15 patients with immune‐checkpoint induced diabetes mellitus (CPI‐DM) with a propensity score matched cohort of patients with other diabetes types. Diabetic ketoacidosis at onset and autoimmune comorbidity is more frequent in CPI‐DM patients. This can be avoided by regular glucose measurements and education on
Sascha R. Tittel +10 more
wiley +1 more source
MMC celebrating 6 years of experience and expansion 庆祝MMC六年的经验和壮大
, 2022 Journal of Diabetes, Volume 14, Issue 5, Page 356-357, May 2022.
Itamar Raz
wiley +1 more source
Ultrasound in Obstetrics &Gynecology, Volume 67, Issue 1, Page 79-88, January 2026.ABSTRACT Objective To evaluate the proportion of optimal assessments of endometrial thickness (ET) achieved by transvaginal ultrasound (TVS) compared with a multimodal (MM) sonographic approach in women with abnormal uterine bleeding (AUB). Methods This prospective observational study was a subset of the EPI‐SURE study conducted between June and ...
S. Nijjar +5 more
wiley +1 more source
Cancer Innovation, Volume 3, Issue 6, December 2024.This study developed a NCC‐BC‐A scale with relatively high validity and reliability for breast cancer (BC) patients. NCC‐BC‐A scale fully considered the characteristics of systemic treatment status for BC and the realistic situation in China, which may help clinicians to pay more attention to QOL of BC patients and to optimize management system for BC.
Fei Ma +4 more
wiley +1 more source
Development and progress of fluorescence imaging technology in diagnosis and treatment of oral cancer [PDF]
, 2023 The main clinical problems in treatment of oral cancer are tumor recurrence and metastasis after surgery. To improve the efficiency of resection and the prognosis of patients is a key to curing oral cancer.
XU Hongtao, HUANG Xiaojuan, ZHENG Chongyang, ZHANG Zhiyuan
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Zhongguo shiyan zhenduanxue, 2014 目的探讨HPV在宫颈炎、宫颈癌前病变、宫颈癌中的检测意义。方法选择我院2009年7月至2013年7月期间收治的慢性宫颈炎患者、宫颈癌前病变患者和宫颈癌患者,分别为88例,86例和46例,分别作为宫颈炎组、癌前病变组和宫颈癌组。癌前病变组分为宫颈上皮内瘤样病变Ⅰ级（38例）、宫颈上皮内瘤样病变Ⅱ级（15例）、宫颈上皮内瘤样病变Ⅲ级（33例）。上述患者经过严格操作取样后检测HPV。结果本文所选的220例患者中,88例慢性宫颈炎患者中,通过HPV检测显示阳性的患者共9例,慢性宫颈炎患者中 ...
曾新, 韩一栩, 吴丽香
doaj
Clinical significance of Twist, Bmi-1 and E-cadherin expression in Cervical Intraepithelial Neoplasia and Early Stage Cervical Cancer [PDF]
, 2015 目的：研究Twist/Bmi-1/E-cadherin蛋白在早期宫颈癌组织、宫颈上皮内瘤变（CIN）组织与正常宫颈组织中的表达水平，探讨Twist/Bmi-1/E-cadherin在早期宫颈癌不同病变组织中表达的生物学意义，对宫颈癌患者预后的影响以及这三者之间的相关性。 方法：收集2009年7月—2013年10月在厦门大学附属中山医院手术切除的64例宫颈癌，41例CIN组织，12例正常宫颈组织石蜡标本，运用Elivision免疫组化法检测Twist/Bmi-1/E-cadherin在宫颈癌组织 ...
丁娅妮
core
Zhongguo shiyan zhenduanxue, 2019 目的研究宫颈病变和宫颈癌患者高危型HPV感染情况、年龄分布及亚型分布,分析高危型HPV感染与宫颈癌前病变及宫颈癌的相关性,为宫颈癌的预防筛查工作提供实验依据。方法按宫颈病变程度将313名宫颈病变患者分为CIN I、CINII、CINIII、宫颈癌4组,检测患者高危型HPV-DNA感染情况。结果 CINI组高危型HPVDNA的阳性率为16.67%,CINII组阳性率为60.38%,CINIII组阳性率为69.74%,宫颈癌组的阳性率最高,为75.42%;癌前病变(CINII-CINIII ...
方莉, 韩瑜, 许媛, 陈莹, 郑阳
doaj
Research of diagnostic biomarkers in Breast cancer and Gastric cancer [PDF]
, 2013 自生物标志物（biomarker）这一概念提出以来，肿瘤生物标志物（tumorbiomarker，TBM）在基础医学领域的研究已成为热点。本文基于大量的临床病理样本，利用免疫组织化学、甲基化芯片分析、实时荧光定量PCR等技术，研究乳腺癌、胃癌预后诊断的生物标志物，为疾病的治疗提供新的思路和靶点。 我们利用免疫组织化学，调查了酪氨酸磷酸酶Shp2和它的伴侣蛋白Gab2在141例乳腺浸润性导管癌中的表达，并分析了他们与临床病理学特征的相关性，发现Gab2蛋白表达与病人的年龄存在显著相关性 ...
陈宝珍
core
外周血microRNA-23b作为胃癌筛查分子标志物的价值和应用研究
Zhongguo shiyan zhenduanxue, 2014 目的观察和分析外周血microRNA-23b作为胃癌筛查分子标志物的应用价值。方法选取100例接受胃镜病理活检者作为研究对象,根据检查结果将其分为三组,确诊为胃癌者列为胃癌组,共纳入46例;确诊为胃癌前病变者列为癌前病变组,共纳入28例;胃粘膜检查结果基本正常者列为对照组,共纳入26例。应用定量real time PCR检测技术对三组研究对象外周血样本中的miRNA-23b表达水平进行检测和比较。结果对照组研究对象的外周血样本的Log2△Ct值显著高于癌前病变组 ...
孙秀静, 张莹, 徐有青
doaj