Results 91 to 100 of about 8,410,436 (169)
浙江大学学报. 农业与生命科学版To explore the allergenic effects of Moringa oleifera leaf protein (MLP) and the anti-allergic effects of polyphenols such as lotus leaf polyphenol extract (LPE) and Polygonatum polyphenol extract (PPE), MLP was extracted to construct a zebrafish food ...
ZHENG Yueyan(郑跃妍) +4 more
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Zhongguo shiyan zhenduanxue, 2016 目的了解胰岛素样生长因子2（IGF-2）、白细胞介素1β（IL-1β）、白细胞介素6（IL-6）、白血病抑制因子（LIF）、血管内皮生长因子（VEGF）、肿瘤坏死因子α（TNF-α）和转化生长因子β1（TGF-β1）7种细胞因子对卵母细胞发育成熟的影响。方法用酶联免疫吸附双抗夹心法（ELISA）检测卵泡液、取卵日血清以及移植日血清中7种细胞因子浓度水平,比较分析7种细胞因子在卵泡液和血清中的浓度水平。结果 （1）IGF-2、IL-6和VEGF卵泡液中的浓度显著高于取卵日血清中的浓度,差异有显著性意义 ...
胡兴文, 王维鹏, 秦柳
doaj
Effects of low-level laser on the expression of interleukin-6, tumor necrosis factor‑α, osteoprotegerin, and receptor activator of nuclear factor-κB ligand in human periodontal ligament cells. [PDF]
Hua Xi Kou Qiang Yi Xue Za Zhi, 2023 Tang M +5 more
europepmc +1 more source
Effect and mechanism of reactive oxygen species-responsive nanoparticles on the regulation of human gingival fibroblast function and inflammation induced by lipopolysaccharide [PDF]
Objective To investigate the effects of PssL-NAC reactive oxygen species (ROS)-responsive nanoparticles on intracellular ROS production, inflammatory factor levels, collagen production, cell function and Toll-like receptor 4 (TLR4), NF-κB nuclear factor ...
QIU Xinyi, SONG Lutong, REN Shuangshuang, MIAO Leiying
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血清PCT、CRP在不同病因的急性腹泻患者中表达水平差异及与预后的相关性分析
Zhongguo shiyan zhenduanxue目的探究不同病因的急性腹泻患者血清降钙素原（PCT）、C反应蛋白（CRP）等炎症水平特征及与预后的相关性。方法选取2022年9月至2024年6月就诊于成都市第一人民医院的急性腹泻患者108例，根据患者是否合并感染划分为非感染性腹泻组（n=22）和感染性腹泻组（n=86）。对比两组患者一般临床资料及不良预后的发生率；对比两组患者PCT、CRP、白细胞介素1（IL-1）、白细胞介素6（IL-6）及白细胞介素8（IL-8）等血清炎症因子水平的差异；对比两组患者中性粒细胞计数（NEU）、淋巴细胞计数（LYM ...
胡馨, 王明皓, 杨虎, 于圣会
doaj
Preventive Effect of Lactobacillus paracasei FZU103 on Alcoholic Liver Injury in Mice [PDF]
Objective: To explore the preventive effect of Lactobacillus paracasei FZU103 (LP-FZU103) on alcoholic liver injury (ALI). Methods: Altogether 36 specific pathogen free- (SPF-) grade ICR mice were randomly divided into three groups: control, model and ...
LIANG Zihua, LI Jiayi, XIE Linhui, YANG Ziyi, YOU Shize, WU Chao, LI Wenlong, AI Lianzhong, NI Li, LÜ Xucong, CHEN Youting
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巨噬细胞ABCA1对Ox-LDL诱导的炎症因子的调节及其意义
Zhongshan Daxue xuebao. Yixue kexue ban, 2007 【目的】研究在氧化低密度脂蛋白(Ox-LDL)诱导作用下,ATP结合盒转运子A1(ABCA1)对巨噬细胞中细胞间黏附分子-1(ICAM-1)、单核细胞化学趋向蛋白-1(MCP-1)mRNA和蛋白质及白介素-1β(IL-1β)蛋白质表达的影响,在细胞水平证实ABCA1对动脉粥样硬化的影响。【方法】用氟波酯(PMA)刺激THP-1细胞使之转变为巨噬细胞,Ox-LDL(30μg/mL)刺激3、6、12、24h后,以荧光定量RT-PCR和Western蛋白印迹法及酶联免疫吸附法(ELISA)检测ABCA1 ...
郭志刚 +3 more
doaj
Zhongguo shiyan zhenduanxue目的 探究Dectin-1通过巨噬细胞极化影响STEMI的机制研究。方法 将45只SPF级SD大鼠随机分为假手术组(n=15)、模型组(n=15)、si-Dectin-1组(n=15),模型组与si-Dectin-1组分别通过尾静脉注射NC-质粒和si-Dectin质粒，2周后建立ST段抬高型心肌梗死(ST-Segment Elevation Myocardial Infarction, STEMI)模型，2周后分离心脏组织，qPCR检测心脏组织Dectin-1表达水平，TTC染色检测心肌坏死面积 ...
孙倩, 苏艳, 张雅兰, 李晓林
doaj
The Mechanism Studies of Ⅰ-IFN in LPS-induced Dendritic Cells Immune Paralysis [PDF]
, 2013 树突状细胞是目前已知功能最强的抗原提呈细胞，然而在细菌性感染以及某些病理条件下，其介导的免疫反应将会受到严重抑制，呈现免疫麻痹状态。Ⅰ型干扰素是一种多功能的细胞因子，可能参与细菌性感染所致免疫麻痹过程，但其作用机制不甚明了。为此，我们以脂多糖（LPS）刺激树突状细胞（DCs）建立抗原交叉提呈免疫麻痹体系，对Ⅰ型干扰素（Ⅰ-IFN）在脂多糖所致树突状细胞免疫麻痹中的作用及所涉及细胞因子和细胞亚群功能转化进行了探讨。对小鼠骨髓来源的DCs给予一定剂量的LPS刺激，联合抗原负载（SIINFEKL ...
王方
core
HIF-1α promotes the inflammatory response of periodontal ligament cells under mechanical stress [PDF]
Objective To investigate the molecular regulatory mechanism of hypoxia-inducible factor-1α (HIF-1α) in mechanical stress-induced inflammatory cytokine expression in human periodontal ligament cells (hPDLCs), providing a theoretical basis and potential ...
WANG Feifei, ZHENG Chengju, CHEN Zhiyun, LIU Ting, WANG Yu
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