Results 51 to 60 of about 790 (102)

SIRT6通过调节eNOS抑制心肌肥大的机制研究

Zhongshan Daxue xuebao. Yixue kexue ban, 2015
摘 要: 【目的】 探讨SIRT6通过调节内皮一氧化氮合酶(eNOS)抑制苯肾上腺素(PE)诱导的新生大鼠心肌细胞肥大的作用及机制? 【方法】 在PE诱导的心肌细胞肥大模型中采用si-RNA干扰或腺病毒过表达的方法改变心肌细胞中SIRT6表达水平,并通过实时定量RT-PCR(real time PCR)?Western Blotting等方法检测心肌肥大基因心钠素(ANF)?脑尿钠肽(BNP)的表达?心肌细胞表面积,以及eNOS的表达及NO的生成?
doaj  

一氧化氮在吗啡后处理对心肌缺血再灌注损伤保护中的作用

Zhongshan Daxue xuebao. Yixue kexue ban, 2010
【目的】 探讨吗啡后处理对急性心肌缺血/再灌注损伤的保护作用以及对信号通路eNOS/NO的影响?【方法】 SD大鼠56只随机分成4组,每组14只: S组(假手术,只穿线,不结扎), I/R组(单纯缺血再灌注), M组(吗啡后处理 + 缺血再灌注),L + M组(L-NAME + 吗啡后处理 + 缺血再灌注)?除S组外,所有大鼠心脏都经历45 min缺血和120 min再灌注?观察血流动力学指标,于再灌注120 min时,各组随机取9只大鼠,用TTC法染色,计算心肌缺血梗死区(IA/AR);其余5只大鼠 ...
doaj  

Comparison of nitrification inhibitors for mitigating cadmium accumulation in pakchoi and their associated microbial mechanisms. [PDF]

J Zhejiang Univ Sci B
DU W, Zhu Q, Jing X, Hu W, Zhuang Y, Jiang Y, Jin C.   +6 more
europepmc   +1 more source

[Heterogeneity of tumor-associated macrophages and precision targeting strategies in hepatocellular carcinoma]. [PDF]

Zhonghua Gan Zang Bing Za Zhi
Huang K, Zhang GQ.
europepmc   +1 more source

[Selenocystine inhibits colon cancer cell growth by promoting reactive oxygen species generation to trigger oxidative damage]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Song Q, Miao Y, Feng X, Wang Y, Liu W, Wei Q, Yu X, Chen W, Fu X.   +8 more
europepmc   +1 more source

[Study on the Inhibitory Effect and Mechanism of Trans-2-Decenal on <i>Helicobacter pylori</i> <i>in vitro</i>]. [PDF]

Sichuan Da Xue Xue Bao Yi Xue Ban
He L, He Q, Tian H, Fu Y, Cai L, Liao J.
europepmc   +1 more source

[Expert consensus on perioperative management of tooth extraction in patients receiving denosumab therapy]. [PDF]

Hua Xi Kou Qiang Yi Xue Za Zhi
Ye L, Cao Y, Sun G, Xue Y, Cui N, Cai Y, Zou D, Tang H, Hu Y, Luo T, Sun L, Gong Z, Zhu F, Zhang F, You M, Guo Y, Wang Y, Wang L, Chen S, Han B, Zhang W, Zhou Q, He Y, Zhao J, Hu K, Liu L, Liu J, Pan J.   +27 more
europepmc   +1 more source

[Nitrosative stress promotes the malignant biological behavior of breast cancer through the glycolytic pathway]. [PDF]

Zhong Nan Da Xue Xue Bao Yi Xue Ban
Wang Y, Gong M, Zhu Y, Xu Y, Hu J, Luo C.   +5 more
europepmc   +1 more source

[Oral homeostasis imbalance under hypoxia]. [PDF]

Hua Xi Kou Qiang Yi Xue Za Zhi
Xu Y, Wang S, Zhou J.
europepmc   +1 more source

[Total Astragalus saponins reduce astrocyte swelling and AQP4 expression following oxygen-glucose deprivation and reoxygenation by inhibiting the p38 pathway]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Yin Q, Lei Y, Wang X, Yang G, Tang Z.
europepmc   +1 more source