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急性肾损伤向慢性肾脏病转化的肾脏脂质代谢特征 附视频

Linchuang shenzangbing zazhi
目的 探讨急性肾损伤（acute kidney injury,AKI）向慢性肾脏病（chronic kidney disease,CKD）转化中肾组织脂质代谢特征。方法 通过肾脏缺血再灌注损伤（ischemia-reperfusion injury,IRI）（双侧肾动脉夹闭30 min）构建AKI向CKD转化的小鼠模型。取第2天、第14天及第28天小鼠肾脏组织，通过超高效液相色谱串联质谱检测不同时间点IRI小鼠与假手术组小鼠肾脏脂质代谢，分析各组间脂质代谢差异 ...
doaj  

[High expression of CFL1 and phospho-CFL1 predicts poor prognosis and promotes migration of colon cancer cells <i>in vitro</i>]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Wang L, Wang X, Zhu J, Jiang B, Xu J, Gao C, Li D, Wang Y, Li X.   +8 more
europepmc   +1 more source

[<i>Xuebijing</i> Injection ameliorates sepsis-associated acute respiratory distress syndrome in mice by upregulating phospholipid transfer protein to regulate macrophage JNK/c-JUN pathway]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Xu L, Pan Y, Wang Y, Chen Z, Jiang W, Yu J, Zheng R.   +6 more
europepmc   +1 more source

[Dietary serine supplementation inhibits the hepatic macrophage AKT/mTOR pathway and improves primary biliary cholangitis]. [PDF]

Zhonghua Gan Zang Bing Za Zhi
Ran Y, Yuan W, Jia H, Wang XY, Liu RY, Li JW, Han ZZ, Shen M, Yang H, Wang SR, Wang BM, Zhou L.   +11 more
europepmc   +1 more source

[Effects of exosomes derived from normoxic or hypoxic human umbilical vein endothelial cells on hypoxia-induced cardiomyocyte injury and cardiac fibroblast activation <i>in vitro</i>]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Xiong X, Yang T, Chen J, Yang X, Chen S, Ruan H, Wang X, Zhang W, Cheng F, Ke X.   +9 more
europepmc   +1 more source

[Effectiveness of cementless total knee arthroplasty with three-dimensional-printed trabecular metal interface]. [PDF]

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi
Chai H, Sun Y, Chen X, Li Y, Li S.
europepmc   +1 more source

[MIS18BP1 regulates epithelial-mesenchymal transition, proliferation, and migration of renal cancer cells <i>via</i> the PI3K/AKT pathway]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Zhao B, Tan X, Liang X, Pan Y, Yuan J, Song W.   +5 more
europepmc   +1 more source

[The E3 ubiquitin ligase KLHL8 degrades HBx protein via the ubiquitin-proteasome pathway and inhibits HBV cccDNA transcription]. [PDF]

Zhonghua Gan Zang Bing Za Zhi
Liu ZH, He XM, Zhao B, Li JQ, Xu KX, Yu HB, Chen J.   +6 more
europepmc   +1 more source

一种基于分组稀疏表示的模式识别分类方法

本发明公开了一种基于分组稀疏表示的模式识别分类方法，该方法包括：通过求解线性方程的最小二乘解获得待识别样本的初始表示；在线性方程的解空间内补偿较小的分组系数，逐步增强解向量在分组稀疏模型意义下的稀疏性，反复迭代直到收敛，获得样本的分组稀疏表示；根据所获得的稀疏解判定待识别样本的类别为对应系数最大的分组，置信度用稀疏解的系数在各分组分布的集中程度来衡量。本发明采用的分组模型更适应分类问题的需要，提高了识别能力，结合解空间内系数补偿的方法，增强了解的稀疏性，减小了计算量。本方法不仅适用于模式识别的分类问题 ...
李卫军, 陈新亮, 王徽蓉
core  

[Thymosin β4 inhibits pyroptosis in BV2 microglial cells: a mechanistic study <i>in vitro</i>]. [PDF]

Zhongguo Dang Dai Er Ke Za Zhi
Li YX, Chen CL, Zheng SD, Lai KX, Yang Z, Deng YY, Guo YX.   +6 more
europepmc   +1 more source