[Expression of Rho-related BTB domain-containing protein 1 in tongue squamous cell carcinoma and its effect on cell proliferation, invasion, and migration]. [PDF]
Shao Y +6 more
europepmc +1 more source
异类叶升麻苷调控PI3K/Akt/mTOR通路抑制人食管鳞状癌ECA109细胞增殖及迁移的机制研究
目的探究异类叶升麻苷基于PI3K/Akt/mTOR信号通路抑制人食管鳞状癌ECA109细胞增殖及迁移的作用机制。方法采用不同浓度异类叶升麻苷处理ECA109细胞,通过CCK-8与克隆形成实验评估细胞增殖活性;根据CCK-8检测结果分为对照组和异类叶升麻苷低(150 μM)、中(300 μM)和高(400 μM)剂量组,通过划痕愈合实验评估细胞迁移能力,Western blot检测细胞PI3K p85、p-PI3K、Akt、p-Akt、mTOR、p-mTOR 蛋白表达及磷酸化水平,RT ...
宋文潇 +4 more
doaj
[MIS18BP1 regulates epithelial-mesenchymal transition, proliferation, and migration of renal cancer cells <i>via</i> the PI3K/AKT pathway]. [PDF]
Zhao B +5 more
europepmc +1 more source
[Anwulignan inhibits malignant phenotypes of gastric cancer cells by antagonizing activation of the JAK1/STAT3 signaling pathway]. [PDF]
Liu X +9 more
europepmc +1 more source
[Hepatocellular carcinoma-derived lactate-mediated histone H3K18 lactylation modifies S100A2 transcription to promote proliferation, migration, invasion and epithelial-mesenchymal transition of hepatocellular carcinoma cells]. [PDF]
Huang L, Shao Y, Zhou W, He J.
europepmc +1 more source
[Metformin Inhibits Prostate Cancer Progression via Regulation of the AKT/mTOR Signaling Pathway]. [PDF]
Zhang Z +11 more
europepmc +1 more source
【目的】 拟探讨肾癌内IL-8的分泌水平及其对骨髓间充质干细胞(MSC)的调节机制,探讨其在归巢中的作用机制?【方法】 ELISA法检测肾癌患者血清以及肾癌细胞分泌的IL-8;免疫组织化学和RT-PCR检测MSC表面IL-8受体表达;迁移实验观察IL-8对MSC的迁移作用;Western blotting 法检测IL-8对MSC内ERK的激活作用?【结果】研究发现正常人群的血液中IL-8为210.4 pg/mL,而肾癌患者血液中IL-8升高至526.7 pg/mL,肾癌细胞株786 ...
doaj
[Mechanisms and applications of magnesium ion-regulated stem cell functions in promoting tendon-bone interface healing]. [PDF]
Zhu X +5 more
europepmc +1 more source
[Anemoside B4 inhibits non-small cell lung cancer metastasis by modulating epithelial-mesenchymal transition mediated by the MAPK and Keap1/Nrf2 signaling pathways]. [PDF]
Su Q +7 more
europepmc +1 more source
[Network pharmacology-based investigation of the therapeutic efficacy and molecular targets of Xiangsha Liujunzi decoction in thyroid carcinoma]. [PDF]
Huang K +6 more
europepmc +1 more source

