[Cannabidiol inhibits neuronal endoplasmic reticulum stress and apoptosis in rats with multiple concussions by regulating the PERK-eIF2α-ATF4-CHOP pathway]. [PDF]
Yang Y +7 more
europepmc +1 more source
[Effects of CACNA1H gene knockout on autistic-like behaviors and the morphology of hippocampal neurons in mice]. [PDF]
Jiao C, Wang JM, Kuang HX, Wu ZH, Liu T.
europepmc +1 more source
[Monotropein improves motor function of mice with spinal cord injury by inhibiting the PI3K/AKT signaling pathway to suppress neuronal apoptosis]. [PDF]
Chen Y +5 more
europepmc +1 more source
A型肉毒毒素调控钠离子通道Nav1.8缓解神经病理性疼痛的作用
摘 要: 【目的】 研究A 型肉毒毒素(BoNT/A)对腰5脊神经前根切断(L5 VRT)介导的神经病理性疼痛的影响,并进一步探讨其可能的内在作用机制?【方法】 利用行为学测试方法观察BoNT/A足底注射后对L5 VRT大鼠机械刺激撤足阈值的影响,采用Western blot方法分析BoNT/A对L5 VRT术后背根神经节(DRG)神经元中钠离子通道(Nav1.8)蛋白表达的影响,并进一步应用全细胞膜片钳技术观察BoNT/A对DRG神经元中功能性Nav1.8电流密度的影响?【结果】 一侧足底注射7?15
doaj
[Enriched environment reduces pyramidal neuron excitability in the anterior cingulate cortex to alleviate restraint stress-induced anxiety-like behaviors in mice]. [PDF]
Chen C, Fang Q, Gao Y, Wang L, Chen L.
europepmc +1 more source
Reprogramming astrocytes into dopaminergic neurons to restore motor dysfunction in Parkinson's disease model rats. [PDF]
Liu C +9 more
europepmc +1 more source
Shuyu capsule improves estrous cycle-dependent depression-like behavior in premenstrual dysphoric disorder (PMDD) mice by increasing GABAergic neuronal activation and downregulating GABAAR δ subunit expression in the dorsal periaqueductal gray (dPAG) region. [PDF]
Xu J +12 more
europepmc +1 more source
miR-210 inhibitor对大鼠背脊髓神经元细胞氧化 应激的保护作用
摘 要:【目的】 观察miR-210 inhibitor对大鼠背脊髓神经元细胞氧化应激的保护作用?【方法】 体外培养大鼠背脊髓神经元细胞,随机分成正常组,H2O2组,H2O2联合miRNA Negative control组以及H2O2联合miR-210 inhibitor组?采用MTT法检测细胞的存活率,流式细胞仪检测细胞的凋亡率,活性氧检测试剂盒检测细胞内活性氧,Elisa检测NOX2?【结果】 qPCR结果显示,100 μmol/L H2O2处理可导致大鼠背脊髓神经元细胞内miR ...
doaj
[Effects of background noise on auditory response characteristics of primary auditory cortex neurons in awake mice]. [PDF]
Song C, Zhao Y, Bai L.
europepmc +1 more source
[PI3K/Akt/Erk signaling pathway mediates neuroprotection of CaMKⅡγ and CaMKⅡδ against ischemic reperfusion injury in mice]. [PDF]
Liu H, Lin Z, Ye J.
europepmc +1 more source

