Results 101 to 110 of about 6,042 (145)

[<i>Lactobacillus plantarum</i> alleviates lead exposure-induced learning and memory impairment in mice by regulating bile acid metabolism and inhibiting hippocampal NLRP3 expression]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Li L, Yu W, Tan M, Li Y, Liu A, Meng X.
europepmc   +1 more source

胚胎干细胞源性与海马源性神经干细胞培养与分化的特性比较 [PDF]

, 2003

core  

Nrf2通过上调自噬促进C17.2神经干细胞的增殖

Zhongshan Daxue xuebao. Yixue kexue ban, 2016
摘 要: 【目的】 通过使用化合物调控细胞内信号通路,最终引起脑内神经干细胞的增殖和分化?这被为认为是一种崭新的修复受损大脑功能的治疗策略?我们发现Nrf2能够调控C17.2神经干细胞的增殖,并试图阐明其可能的作用机制?【方法】 采用MTT法检测细胞活力,BrdU掺入法检测细胞增殖,western blot法检测细胞内蛋白水平的变化,流式细胞术检测细胞内ROS水平的变化?【结果】 Nrf2的激动剂t-BHQ和SFN可以促进C17.2神经干细胞的增殖,而使用Nrf2的抑制剂brusatol则抑制其增殖 ...
doaj  

[Advances on efficacy and mechanisms of acid fibroblast growth factor for promoting injured tissue repair]. [PDF]

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi
Zhu F, Jiang Z, Qian X, Xu Y, Cheng H, Zhang J.   +5 more
europepmc   +1 more source

成人骨髓间质干细胞分化为神经元样细胞及与凋亡的关系

Zhongshan Daxue xuebao. Yixue kexue ban, 2004
【目的】探讨体外诱导成人骨髓间质干细胞(humanmesenchymalstemcells,hMSC)向神经元样细胞分化过程中分化与凋亡的关系,为进一步研究延长神经元样细胞的存活时间提供基础。【方法】从成人骨髓分离MSC,培养扩增。以β-巯基乙醇和参芪液诱导分化,于诱导后1、3、5h分别进行免疫组化鉴定神经元烯醇化酶(NSE)、神经丝蛋白(NF)、胶质纤维酸性蛋白(GFAP)的表达,计数神经元样细胞,计算分化率。采用TUNEL方法分别检测诱导后1、3、5h的细胞凋亡率,并分析两者是否相关。【结果 ...
doaj  

[Sulforaphane reduces reactive astrocyte-mediated neuron apoptosis <i>in vitro</i> by inhibiting the MAPK/NF-κB signaling pathway in Aβ42 oligomer-activated astrocytes]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Zhang S, Huang T, Yang C, Chen J, Lü T, Zhang J.   +5 more
europepmc   +1 more source

[Research advances on hepatic encephalopathy following transjugular intrahepatic portosystemic shunt]. [PDF]

Zhonghua Gan Zang Bing Za Zhi
Ye JJ, Pan YL, Wang J, Lyu Y.
europepmc   +1 more source

[Oral homeostasis imbalance under hypoxia]. [PDF]

Hua Xi Kou Qiang Yi Xue Za Zhi
Xu Y, Wang S, Zhou J.
europepmc   +1 more source

[Kahweol improves motor function of mice with spinal cord injury by inhibiting microglial activation <i>via</i> regulating the IκBα/NF-κB pathway]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Xia J, Chen Y, Ren L, Li J, Song X, Tao L, Hu J.   +6 more
europepmc   +1 more source

[Association Between T Lymphocyte Mitochondrial Function and Disease Activity in Anti-NMDAR Encephalitis]. [PDF]

Sichuan Da Xue Xue Bao Yi Xue Ban
Ma Y, Zhang E, Cao L, Wang Z, Wang M, Li F, Ying B, Yan L.   +7 more
europepmc   +1 more source