脊髓损伤(SCI)是一种常见的神经系统疾病,通常导致运动、感觉、认知、平衡、步行等功能障碍,甚至会引起疼痛,严重影响患者的身心健康和生活质量。常规治疗方法单一枯燥、缺乏趣味性,导致患者的依从性差,治疗积极性和配合度不高,且主要在医院进行;而虚拟现实(VR)技术可作为一种有效的辅助治疗手段,通过模拟的虚拟环境让患者沉浸其中,进行特定环境和任务的功能训练,获得真实体验感,以达到评估、治疗的效果。VR技术具有趣味性和交互性,显著提高了患者治疗的兴趣和积极性,并为居家康复治疗提供了新的可能性 ...
张贝贝, 任亚锋
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Zhang W, Yang L, Zhang R.
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TFOS DEWS III诊断方法学:Republishing of TFOS DEWS III: Diagnostic Methodology [PDF]
Benítez-Del-Castillo, José +18 more
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临床上抑郁与慢性疼痛经常共同出现。然而在实验室条件下,抑郁患者的疼痛反应却反而减弱。我们在大鼠建立的慢性不确定温和应激、嗅球切除两种抑郁模型上,利用热辐射、热接触、机械压力、福尔马林刺激等多种测痛手段,并同时建立了福氏佐剂炎症痛和腰 5脊神经结扎神经病理痛模型,考察了其疼痛行为的改变。结果表明,具有抑郁样行为的动物,对实验性可回避的疼痛刺激的反应减弱,表现为痛阈升高,回避潜伏期延长;甚至在慢性炎症性疼痛和神经病理性疼痛这两种动物模型中,也有类似的现象。然而,在不可回避的疼痛刺激如福尔马林疼痛模型中 ...
罗非
core
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