Results 31 to 40 of about 9,176 (149)
The Effects and Mechanisms of JMJD1A on Colorectal Tumorigenesis [PDF]
, 2015 结直肠癌（colorectalcancer，CRC）是当今世界高发恶性肿瘤之一，多数由散发腺瘤阶段性发展而来，少数结肠癌的发生呈家族性聚集现象或由炎性肠病诱导发生。对结肠癌的早期筛查与诊断是结肠癌防治重点，由于结肠癌患者个体间差异性大，对靶向药物的开发是未来结肠癌治疗的重要辅助手段。 组蛋白去甲基化酶JMJD1A(Jumonjidomaincontaining1A)通过羟基化作用使组蛋白赖氨酸去甲基进而行使转录调节功能，参与精子生成、能量代谢、干细胞更新调控，也参与低氧诱导下的肿瘤调控 ...
苗萌萌
core
World Medical &Health Policy, Volume 17, Issue 3, Page 389-410, September 2025.ABSTRACT Despite the high prevalence of cervical and breast cancer, screening rates remain low in low‐income countries. Using nationally representative data, we examine factors associated with knowledge and uptake of cervical and breast cancer screening among married women ages 30–49 in Nepal.
Young‐ji Lee +2 more
wiley +1 more source
Zhongguo shiyan zhenduanxue, 2011 目的根据老年尿毒症患者的特点,通过手术前各项指标的严格诊断性筛查,提高肾移植手术的成功率及移植后人/肾的长期存活率。方法常规诊断性筛查组:2007年10月至2008年10月间,对在我院行肾移术的20例60岁以上老年尿毒症患者,术前进行常规诊断性筛查;严格诊断性筛查组:2008年10月至2009年10间,对在我院行肾移植术的23例60岁以上老年尿毒症患者,术前进行严格诊断性筛查。通过各项检查结果诊断患者有无肾移植禁忌症;对于通过常规诊断性筛查,但未达到严格诊断性筛查标准的老年尿毒症患者,给予充分透析 ...
翟秀宇, 孙玲, 翟成伟, 王远涛
doaj
hsa-miR-125a-5p Enhances Invasion Ability in Non-Small Lung Carcinoma Cell Lines [PDF]
, 2009 Background and objective MicroRNAs (miRNAs) are short non-coding RNAs that posttranscriptionally regulate gene expression by partially binding complementary to target sites in mRNAs.
Enhua WANG +4 more
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Veterinary Dermatology, Volume 36, Issue 4, Page 474-484, August 2025.Background – Sporotrichosis is a chronic, mycotic infection caused by fungi of the genus Sporothrix. Zoonotic sporotrichosis occurs mainly through S. brasiliensis transmission, resulting from the organism's traumatic introduction via scratches or bites, or contact with exudate from contaminated cats.
Steffanie Amadei +6 more
wiley +1 more source
Screening of β-thalassemia trait among pregnant women with NESTROFT
Thalassemia Reports, 2015 The morbidity of β-thalassemia major has forced medical professionals to formulate screening tests to effectively screen β-thalassemia trait (BTT) of which naked eye single tube osmotic fragility test (NESTROFT) is the most cost effective test.
Hitesh Sarda +2 more
doaj +1 more source
Ultrasound in Obstetrics &Gynecology, Volume 66, Issue 1, Page 24-32, July 2025.ABSTRACT Objectives To investigate the impact of aspirin administration on the incidence of preterm birth, according to the type of delivery and gestational age at preterm birth, and to examine the hypothesis that aspirin delays preterm delivery. Methods This was a secondary analysis of a multicenter stepped‐wedge cluster randomized trial of a first ...
H. H. Y. Leung +29 more
wiley +1 more source
Zhongguo shiyan zhenduanxue, 2015 目的探讨全自动毛细管微量血红蛋白电泳技术在新生儿β地中海贫血筛查中的应用价值,并寻求有效的筛查方法。方法使用Sebia全自动毛细管电泳仪对145904例新生儿滤纸干血斑标本进行血红蛋白（Hb）电泳;对95059例标本的电泳分析结果以HbA界值法判读β地贫筛查结果,对50845例标本的电泳分析结果以HbA值结合HbA2/HbA比值的综合分析法判读β地贫筛查结果,召回筛查阳性者进行地贫基因诊断;随机对600份标本的电泳结果同时以上述两种方法判读β地贫筛查结果,同时进行基因检测作为β地贫诊断的金标准 ...
黄烁丹 +8 more
doaj
MNK, IRR and FGFR genes in Haliotis diversicolor: molecular cloning, expression analysis and identification of SNPs associated with growth traits [PDF]
, 2015 杂色鲍（Haliotisdiversicolor）是我国南方重要的养殖鲍种，研究与杂色鲍生长相关的基因，分析基因的表达规律，并筛查基因中与生长性状相关联的SNP位点，对于深入了解生长性状调控的分子机制，培育具有优良性状的新品种具有重要意义。本研究将MAPK互作激酶（MAPkinase-interactingkinase,MNK）、胰岛素相关多肽受体（Insulin-relatedpeptidereceptor,IRR）和成纤维细胞生长因子受体（Fibroblastgrowthfactorreceptor,
何佩茹
core
Assessment of risk for pre‐eclampsia at mid‐gestation to define subsequent care
Ultrasound in Obstetrics &Gynecology, Volume 65, Issue 6, Page 694-702, June 2025.ABSTRACT Objective To stratify pregnancy care based on the estimated risk of pre‐eclampsia (PE) from screening at 19–24 weeks' gestation by combinations of maternal risk factors, estimated fetal weight (EFW), mean arterial pressure (MAP) and uterine artery pulsatility index (UtA‐PI).
S. Adjahou +5 more
wiley +1 more source