Results 61 to 70 of about 2,459 (149)

[Identification of high-risk preoperative blood indicators and baseline characteristics for multiple postoperative complications in rheumatoid arthritis patients undergoing total knee arthroplasty: a multi-machine learning feature contribution analysis]. [PDF]

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi
Zhu K, Huang Z, Wang B, Li H, Wu Y, Shen B, Nie Y.   +6 more
europepmc   +1 more source

[Diabetic Charcot neuroarthropathy initially misdiagnosed as rheumatoid arthritis and gout: A case report]. [PDF]

Beijing Da Xue Xue Bao Yi Xue Ban
Gu J, Li X, Zhao J, Mu R.
europepmc   +1 more source

靶向IL-6通路治疗免疫介导的炎症性疾病：从机制到临床

Zhongshan Daxue xuebao. Yixue kexue ban
免疫介导的炎症性疾病（IMIDs）是一大类由免疫系统异常激活导致的慢性炎症性疾病，其特征是促炎细胞因子过度释放和抗炎调节信号不足的失衡。白细胞介素6（IL-6）是一种多效性细胞因子，因其独特的“三位一体”信号传导机制（经典途径、反式信号传导和反式呈递）而成为连接固有免疫与适应性免疫的“分子桥梁”。IL-6信号通路驱动急性相炎症反应，并以多种机制参与固有免疫的激活及适应性免疫调控，是驱动IMIDs炎症反应、导致多器官损害的关键途径。靶向IL-6通路的药物通过精准阻断IL-6/IL-6受体/gp130信号轴，
吴滔, 戴冽
doaj  

[Role of Trained Immunity in the Association Between Periodontitis and Rheumatoid Arthritis]. [PDF]

Sichuan Da Xue Xue Bao Yi Xue Ban
You R, Cui Y, Sun J.
europepmc   +1 more source

焦孔素D介导的滑膜血管内皮细胞焦亡促进类风湿关节炎关节破坏

Zhongshan Daxue xuebao. Yixue kexue ban
目的了解焦孔素D（GSDMD）在类风湿关节炎（RA）滑膜血管内皮细胞（VEC）中的表达并探讨其介导的细胞焦亡对VEC功能的影响。方法收集22例RA及对照组18例非炎性关节病（Orth.A）患者膝关节滑膜，Western blot方法检测活性GSDMD-NT段蛋白水平并分组比较RA患者临床指标的差异；免疫荧光双染检测RA滑膜GSDMD的细胞定位。体外RA滑液干预人脐静脉血管内皮细胞（HUVEC）模拟炎症环境，检测细胞凋亡水平及焦亡通路相关蛋白表达。siRNA转染敲减GSDMD，检测HUVEC细胞焦亡 ...
吴滔, 张学培, 卢烨, 邹耀威, 欧阳志明, 马剑达, 戴冽   +6 more
doaj  

[Single-cell RNA sequencing of B cells reveals molecular typing in Sjögren syndrome]. [PDF]

Beijing Da Xue Xue Bao Yi Xue Ban
Lin W, Xie Y, Wang F, Wang S, Liu X, Hu F, Jia Y.   +6 more
europepmc   +1 more source

[Mechanisms and protective strategies for astronaut skin injury in deep space environments]. [PDF]

Zhong Nan Da Xue Xue Bao Yi Xue Ban
Xie Y, Zeng J.
europepmc   +1 more source

[Untargeted metabolomics reveals differential serum metabolites and metabolic pathways in patients with primary Sjögren syndrome and thrombocytopenia]. [PDF]

Beijing Da Xue Xue Bao Yi Xue Ban
Xiang Z, Yang L, Yang J.
europepmc   +1 more source

[Integrative Analysis of Multi-source Public Databases to Screen Core Genes 
for Constructing A Prognostic Risk Model in Lung Adenocarcinoma]. [PDF]

Zhongguo Fei Ai Za Zhi
Wang C, Zhang L, Zhang Y, Wang Y, Wang M.   +4 more
europepmc   +1 more source

[Clinical efficacy and safety of rituximab in treating renal injury in primary Sjögren syndrome]. [PDF]

Beijing Da Xue Xue Bao Yi Xue Ban
Zhao Y, Ni M, Li X, Wang B, Cheng G, He J, Jin Y.   +6 more
europepmc   +1 more source