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视网膜神经血管单元自噬:糖尿病视网膜病变的新视角 [PDF]

open access: yesJournal of Diabetes, 2023
Diabetic retinopathy (DR) is one of the most prevalent retinal disorders worldwide, and it is a major cause of vision impairment in individuals of productive age.
Xiongyi Yang   +6 more
doaj   +3 more sources

在真实世界研究中深度学习算法在糖尿病视网膜病变诊断中的分层分析 [PDF]

open access: yesJournal of Diabetes, 2022
Background The aim of our research was to prospectively explore the clinical value of a deep learning algorithm (DLA) to detect referable diabetic retinopathy (DR) in different subgroups stratified by types of diabetes, blood pressure, sex, BMI, age ...
Na Li   +15 more
doaj   +3 more sources

纳豆激酶对糖尿病视网膜病变微血管病变和神经炎症的保护作用 [PDF]

open access: yesJournal of Diabetes, 2023
Aims Diabetic retinopathy (DR) is a significant global public health concern. Alternative, safe, and cost‐effective pharmacologic approaches are warranted.
Zijing Huang   +11 more
doaj   +2 more sources

计算机化甲襞视频毛细血管镜在2型糖尿病中的运用: 对102例门诊患者的横断面研究

open access: yesJournal of Diabetes, 2023
Background Type 2 diabetes (T2D) is a chronic disease that negatively affects vascular health. A careful assessment of chronic complications, including microcirculation, is mandatory.
Giuseppe Lisco, Vincenzo Triggiani
doaj   +2 more sources

甲襞毛细血管镜检测与深度学习在糖尿病中的应用

open access: yesJournal of Diabetes, 2023
Objective To determine whether nailfold capillary images, acquired using video capillaroscopy, can provide diagnostic information about diabetes and its complications.
Reema Shah   +6 more
doaj   +2 more sources

2 型糖尿病患者合并肾脏疾病的临床病理及预后 [PDF]

open access: yesZhongshan Daxue xuebao. Yixue kexue ban, 2020
【目的】探讨 2 型糖尿病(T2DM)患者合并肾脏疾病的临床病理特点及预后。【方法】回顾性分析120 例尿检异常和(或)Scr 升高并接受肾活检的2 型糖尿病患者的临床病理资料,并进行了随访。肾脏结局的定义是接受肾脏替代治疗或进入到终末期肾病(ESRD)。Kaplan-Meier 分析用于比较肾存活率,Cox 比例风险分析用于进行糖尿病肾病(DN)和非糖尿病肾脏疾病(NDRD)进入 ESRD 的风险比较。【结果】120 例 2 型糖尿病患者中,肾穿刺确诊DN57 例,占47.5%;NDRD63 例 ...
李明   +5 more
doaj   +2 more sources

N-cadherin对视网膜色素上皮细胞增殖及迁移侵袭的影响 [PDF]

open access: yesZhongshan Daxue xuebao. Yixue kexue ban, 2019
【目的】为了明确神经钙黏蛋白(N-cadherin)在糖尿病视网膜病变上皮-间质转化中的作用,探讨N-cadherin对视网膜色素上皮细胞增殖、迁移及侵袭力的影响及作用机制。【方法】分别采用Ad-N-cadherin(Ad-N-cad)、Ad-si N-cadherin(si N-cad)及Ad-GFP、Ad-si Control(si Con)对照腺病毒处理细胞以过表达或沉默N-cadherin,采取葡萄糖(25mmol/L)处理视网膜色素上皮细胞以模拟高糖状态,使用CCK8试剂检测细胞增殖情况 ...
李艳梅
doaj   +2 more sources

慢性肾脏病3-4期糖尿病肾脏疾病患者进展到终末期肾病的危险因素分类树模型分析 [PDF]

open access: yesZhongshan Daxue xuebao. Yixue kexue ban, 2019
【目的】分析糖尿病肾脏疾病(DKD)患者进展到终末期肾病(ESRD)的相关危险因素,筛查进展到ESRD的高风险人群,以早期预防。【方法】收集本院231例糖尿病肾脏疾病患者的临床资料,随访3年,据是否出现ESRD分为未进展到ESRD(133例)、ESRD组(98例)。使用分类树模型分析进展到ESRD相关危险因素,通过节点增益分析筛选进展到ESRD的高风险人群。【结果】从预测变量中筛选到4个重要解释变量:载脂蛋B(ApoB)、性别、糖尿病视网膜病变、收缩压;ApoB升高是DKD进展的重要的危险因素;ApoB>
doaj   +2 more sources

Study of the correlation between ApoB/ApoA1 and vitreous hemorrhage secondary to diabetic retinopathy [PDF]

open access: yes, 2023
Objective To investigate the correlation between ApoB/ApoA1 and vitreous hemorrhage (VH) secondary to diabetic retinopathy (DR). Methods 187 patients with DR from August 2021 to December 2022 were recruited and divided into VH (n=96) and non-VH groups (n=
Dan Yujiao, Zhang Ling, Chen Bin
core   +1 more source

The use of nomogram for detecting mild cognitive impairment in patients with type 2 diabetes mellitus 使用列线图筛查2型糖尿病轻度认知障碍

open access: yesJournal of Diabetes, Volume 15, Issue 5, Page 448-458, May 2023., 2023
Highlights Almost one in three patients with type 2 diabetes mellitus suffered from mild cognitive impairment. Age, marital status, household income, diabetes duration, diabetic retinopathy, anxiety, and depression were associated with mild cognitive impairment.
Rehanguli Maimaitituerxun   +9 more
wiley   +1 more source

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