Results 11 to 20 of about 1,642 (150)
Highlights Different microvascular phenotypes were detected by noninvasive optical coherence tomography angiography (OCTA) in metabolically healthy obesity and metabolic syndrome patients. Baseline blood pressure and insulin status may be key determinants for vascular benefit from bariatric surgery.
Yaying Chen+11 more
wiley +1 more source
Highlights In asymptomatic type 2 diabetic patients with preserved left ventricular ejection fraction, a negative correlation of glycated hemoglobin with subclinical left ventricular systolic dysfunction was revealed. Furthermore, glycated hemoglobin may make prognostic significance for the progression of myocardial damage. Abstract Background We aimed
Yanyan Chen+14 more
wiley +1 more source
HighlightsAssociation of lipid variability with diabetic microvascular complications. Abstract Background Greater lipid variability may cause adverse health events among diabetic patients. We aimed to examine the effect of lipid variability on the risk of diabetic microvascular outcomes among type 2 diabetes mellitus patients.
Daniel Nyarko Hukportie+6 more
wiley +1 more source
Diabetic retinopathy is an ophthalmic disease, a complication of diabetes, with a high incidence, affecting patients' daily life and reducing their quality of life.
XING Hui (兴慧)+3 more
doaj +1 more source
目的:评价中药干预糖尿病视网膜病变(DR)的疗效。方法:运用循证医学Cochrane系统评价方法,检索Pub Med、中国知网(CNKI)2010-2016年间发表的有关中药治疗DR的文献,由2位评价者独立筛选文献、数据提取和评价纳入研究的偏倚风险后,采用Rev Man5.3软件进行Meta分析。结果:共纳入17篇文献,共1756余例患者。Meta分析结果显示,中药组对临床疗效、视力、中医证候、眼底、视网膜循环时间效应、视网膜毛细血管渗漏范围、视网膜毛细血管无灌注区的效应均较对照组效果为佳。结论 ...
刘素嬛, 杨叔禹, 黄曙文
core +1 more source
Clinical effect of salmeterol/fluticasone propionate in the treatment of chronic obstructive pulmonary disease and the influence on pulmonary function [PDF]
目的探讨沙美特罗/丙酸氟替卡松治疗慢性阻塞性肺疾病(COPD)的临床疗效及其对肺功能的影响。方法选取厦门大学医院2014年1月—2016年5月收治的稳定期COPD患者56例,按照就诊顺序分为试验组与对照组,各28例。试验组患者予以沙美特罗/丙酸氟替卡松干粉吸入剂治疗,对照组予以沙丁胺醇气雾剂和丙酸倍氯米松气雾剂治疗,两组患者持续治疗12周。比较两组患者改良版英国医学研究委员会量表(m MRC)评分、肺功能指标[用力肺活量(FVC)、第1秒用力呼气容积(FEV_1)、FEV_1/FVC ...
黄炜坤
core +1 more source
Comparison of Clinical Efficacy and Safety of Azithromycin and β-Lactam Antibiotics in Children With Pneumonia [PDF]
目的对肺炎患儿采取阿奇霉素或β-内酰胺类抗生素治疗的临床疗效和安全性进行研究。方法选取2016年1—12月来我院就诊的1~5岁肺炎患儿100例,按照随机数字表法将其分为实验组和对照组,各组50例。将使用β-内酰胺类抗生素治疗的患儿作为对照组,将使用阿奇霉素治疗的患儿作为实验组。对两组临床有效性及安全性进行比较。结果实验组肺炎患儿肺部湿罗音消失时间、住院时间相比于对照组肺炎患儿,明显较短(P〈0.05);实验组患儿的临床效果优于对照组(P〈0.05)。对比两种治疗方法的费用,差异有统计学意义(P〈0.05)
陈叶莉
core +1 more source
Highlights This study suggests that basal insulin‐supported oral antidiabetic drugs (OADs) therapy is superior to OADs alone in preventing diabetic retinopathy. This will help clinicians to select a suitable subsequent therapy after initial intensive insulin therapy. Abstract Background In this study, we compared the effect on diabetic retinopathy (DR)
Pan‐Wei Mu+12 more
wiley +1 more source
循环胆红素水平与新诊断非增殖期糖尿病视网膜病变及其危险因素相关性的病例对照研究
目的本研究旨在评估循环胆红素谱[总胆红素(TBIL)、结合胆红素(DBIL)、未结合胆红素(IBIL)]与非增殖期糖尿病视网膜病变(NPDR)的相关性。方法采用病例对照研究设计,通过人工智能眼底相机对2型糖尿病患者视网膜病变情况进行筛查,并由眼科医生进一步阅片确认病例。最终纳入312名2型糖尿病(T2DM)患者(78例新诊断的NPDR患者与234例无糖尿病视网膜病变的T2DM患者进行1:3匹配)。同时收集患者人口学和相关临床资料,检测患者血清胆红素及相关生化指标。结果NPDR患者的TBIL ...
刘元桦+7 more
doaj
Involvement of G6PD in diabetic retinopathy and hypoxia induced endothelial lesion and its underlying mechanism [PDF]
研究目的:糖尿病视网膜病变(DiabeticRetinopathy,DR)是发达国际成人致盲的主要原因,其发病机制尚不十分明确。磷酸戊糖途径(PentosePhosphatePathway,PPP)又叫磷酸己糖支路,是糖代谢的重要分支。大量研究表明磷酸戊糖途径在肿瘤的发生,细胞的增殖和抗氧化中发挥重要作用。N-乙酰半胱氨酸(N-acetyl-L-cysteine,NAC)有很好的抗氧化和抗炎作用,多年来在临床上用于治疗急性咳嗽呼吸道疾病,亦有研究表明NAC具有提高G6PD活性的作用 ...
杨晨
core