Results 11 to 20 of about 1,415 (121)

Autophagy in the retinal neurovascular unit: New perspectives into diabetic retinopathy. [PDF]

J Diabetes, 2023
HighlightsAutophagy is closely related to retinal neurovascular units in diabetes retinopathy. Different cells participate in the occurrence and development of diseases through autophagy, and targeted autophagy may be a new direction of treatment in the future. Emphasized the close relationship between diabetic retinopathy (DR) and autophagy Summarized
Yang X, Huang Z, Xu M, Chen Y, Cao M, Yi G, Fu M.   +6 more
europepmc   +2 more sources

A stratified analysis of a deep learning algorithm in the diagnosis of diabetic retinopathy in a real-world study. [PDF]

J Diabetes, 2022
Highlights Our deep learning algorithm (DLA)‐based diabetic retinopathy (DR) grading software showed excellent performance in detecting referable DR, especially in patients with type 1 diabetes and diabetic nephropathy who were prone to DR. The DLA showed consistent performance in the detection of referable DR across different subgroups stratified by ...
Li N, Ma M, Lai M, Gu L, Kang M, Wang Z, Jiao S, Dang K, Deng J, Ding X, Zhen Q, Zhang A, Shen T, Zheng Z, Wang Y, Peng Y.   +15 more
europepmc   +2 more sources

Computerized nailfold video‐capillaroscopy in type 2 diabetes: A cross‐sectional study on 102 outpatients 计算机化甲襞视频毛细血管镜在2型糖尿病中的运用: 对102例门诊患者的横断面研究

Journal of Diabetes, Volume 15, Issue 10, Page 890-899, October 2023., 2023
Highlights Patients with type 2 diabetes (T2D) are prone to developing chronic diabetes‐related complications at the microvascular and macrovascular levels. The Computerized Nailfold Video‐Capillaroscopy (CNVC) provides specific information on both quantitative and qualitative characteristics of microvasculature at the level of fingers.
Giuseppe Lisco, Vincenzo Triggiani
wiley   +1 more source

The use of nomogram for detecting mild cognitive impairment in patients with type 2 diabetes mellitus 使用列线图筛查2型糖尿病轻度认知障碍

Journal of Diabetes, Volume 15, Issue 5, Page 448-458, May 2023., 2023
Highlights Almost one in three patients with type 2 diabetes mellitus suffered from mild cognitive impairment. Age, marital status, household income, diabetes duration, diabetic retinopathy, anxiety, and depression were associated with mild cognitive impairment.
Rehanguli Maimaitituerxun, Wenhang Chen, Jingsha Xiang, Yu Xie, Atipatsa C. Kaminga, Xin Yin Wu, Letao Chen, Jianzhou Yang, Aizhong Liu, Wenjie Dai   +9 more
wiley   +1 more source

Sleeve gastrectomy improved microvascular phenotypes from obesity cohort, detected with optical coherence tomography angiography 通过光学相干断层扫描血管成像检测发现袖状胃切除术改善肥胖队列的微血管表型

Journal of Diabetes, Volume 15, Issue 4, Page 313-324, April 2023., 2023
Highlights Different microvascular phenotypes were detected by noninvasive optical coherence tomography angiography (OCTA) in metabolically healthy obesity and metabolic syndrome patients. Baseline blood pressure and insulin status may be key determinants for vascular benefit from bariatric surgery.
Yaying Chen, Yanyang Liu, Lin Cong, Ailin Liu, Xiangyuan Song, Wenting Liu, Rong Hua, Qiwei Shen, Yikai Shao, Yiwen Xue, Qiyuan Yao, Yuyan Zhang   +11 more
wiley   +1 more source

Assessment of subclinical left ventricular systolic dysfunction in patients with type 2 diabetes: Relationship with HbA1c and microvascular complications 2型糖尿病患者亚临床左心室收缩功能障碍的评估:与糖化血红蛋白和微血管并发症的关系

Journal of Diabetes, Volume 15, Issue 3, Page 264-274, March 2023., 2023
Highlights In asymptomatic type 2 diabetic patients with preserved left ventricular ejection fraction, a negative correlation of glycated hemoglobin with subclinical left ventricular systolic dysfunction was revealed. Furthermore, glycated hemoglobin may make prognostic significance for the progression of myocardial damage. Abstract Background We aimed
Yanyan Chen, Ying Zhang, Yi Wang, Shengjun Ta, Min Shi, Yingni Zhou, Mengying Li, Jianfang Fu, Li Wang, Xiangyang Liu, Zuowei Lu, Liwen Liu, Zeping Li, Jie Zhou, Xiaomiao Li   +14 more
wiley   +1 more source

Nailfold capillaroscopy and deep learning in diabetes 甲襞毛细血管镜检测与深度学习在糖尿病中的应用

Journal of Diabetes, Volume 15, Issue 2, Page 145-151, February 2023., 2023
Highlights Nailfold capillary images were obtained by performing nailfold video capillaroscopy in 120 adult patients with and without diabetes. Over 5000 photographs were analyzed using machine‐learning approaches, and these models were clearly able to distinguish people based on diabetes status.
Reema Shah, Jeremy Petch, Walter Nelson, Karsten Roth, Michael D. Noseworthy, Marzyeh Ghassemi, Hertzel C. Gerstein   +6 more
wiley   +1 more source

Lipid variability and risk of microvascular complications in Action to Control Cardiovascular Risk in Diabetes (ACCORD) trial: A post hoc analysis 控制糖尿病心血管风险的行动(ACCORD)试验中的血脂变异性和微血管并发症风险:一项事后分析

Journal of Diabetes, Volume 14, Issue 6, Page 365-376, June 2022., 2022
HighlightsAssociation of lipid variability with diabetic microvascular complications. Abstract Background Greater lipid variability may cause adverse health events among diabetic patients. We aimed to examine the effect of lipid variability on the risk of diabetic microvascular outcomes among type 2 diabetes mellitus patients.
Daniel Nyarko Hukportie, Fu‐Rong Li, Rui Zhou, Jia‐Zhen Zheng, Xiao‐Xiang Wu, Meng‐Chen Zou, Xian‐Bo Wu   +6 more
wiley   +1 more source

Effect of basal insulin supplement therapy on diabetic retinopathy in short‐duration type 2 diabetes: A one‐year randomized parallel‐group trial 在短病程2型糖尿病患者的治疗方案中增加基础胰岛素对糖尿病视网膜病变的影响:一项1年随机平行对照临床研究

Journal of Diabetes, Volume 11, Issue 12, Page 949-957, December 2019., 2019
Highlights This study suggests that basal insulin‐supported oral antidiabetic drugs (OADs) therapy is superior to OADs alone in preventing diabetic retinopathy. This will help clinicians to select a suitable subsequent therapy after initial intensive insulin therapy. Abstract Background In this study, we compared the effect on diabetic retinopathy (DR)
Pan‐Wei Mu, Xi‐Xiang Tang, Ying Tan, Yi‐Na Wang, Shuo Lin, Man‐Man Wang, Jiong Shu, Jing Wang, Yong‐Jun Zhang, Hua Liang, Bai‐Run Lin, Meng‐Yin Cai, Yan‐Ming Chen   +12 more
wiley   +1 more source

氢谱磁共振代谢组学在2型糖尿病特征代谢物监测中的应用 [PDF]

, 2018
目的应用氢谱磁共振(~1H-NMR)代谢组学方法研究2型糖尿病(T2DM)患者尿液中小分子代谢物代谢轮廓的变化。方法选择T2DM患者98例及健康对照组82例,利用~1H-NMR方法检测尿液的代谢轮廓,结合偏最小二乘判别分析法的模式识别分析方法,比较两组尿液中小分子代谢物差异。结果尿液的偏最小二乘判别分析法得分图显示与T2DM有关的特征代谢物包括乙酸、乳酸、牛磺酸、乙酰乙酸、葡萄糖、丙氨酸、甲基丙二酸、肌酐、柠檬酸、三甲胺等。结论糖代谢紊乱、氧化应激、氨基酸及脂类代谢异常 ...
张志军, 董继扬, 马红
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