IL-10在系统性红斑狼疮患者PBMC B细胞刺激因子表达中的作用 [PDF]
Zhongshan Daxue xuebao. Yixue kexue ban, 2007 【目的】探讨系统性红斑狼疮(SLE)患者外周血单个核细胞(PBMCs)B细胞刺激因子(Blys)基因和蛋白在体外的表达及IL-10对其表达的影响。【方法】梯度密度离心法分离25例系统性红斑狼疮患者和20名女性健康志愿者外周血单个核细胞,分为2组,IL-10(100ng/mL)组和培养基组(仅含RPMI1640培养基),分别于培养0、6、12、24、72h离心收集PBMCs,RT-PCR法检测刺激后0～24h细胞Blys mRNA表达,流式细胞仪和直接免疫荧光法检测72h膜结合型Blys蛋白表达。【结果 ...
叶玉津 +6 more
doaj +2 more sources
Expression and clinical significance of serum complement and IL-25 in systemic lupus erythematosus [PDF]
, 2022 Objective To determine the differences in the expression of serum complement （C） and IL-25 in systemic lupus erythematosus （SLE） involved with single or multi-organ systems， and analyze the correlation between serum C3， C4， CH50， IL-25， C-reactive ...
Wang Yang, Luo Yuhong, Liao Yuan
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Expression and clinical significance of PLA2G2A in kidney renal papillary cell carcinoma [PDF]
, 2023 Objective·To investigate the expression and clinical significance of phospholipase A2 Group ⅡA (PLA2G2A) in kidney renal papillary cell carcinoma (KIRP), and provide new ideas for seeking KIRP targets.Methods·The expression level of PLA2G2A in pan-cancer
LI Fang +5 more
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Zhongguo shiyan zhenduanxue, 2021 目的探讨系统性红斑狼疮患者几种实验室指标在早期肾损伤中的应用价值及肾损伤危险因素。方法以2016年1月至2019年12月入住青岛市市立医院,初诊系统性红斑狼疮患者为研究对象,探讨各相关指标在系统性红斑狼疮肾损伤患者中的改变。结果 IgG、IgA、Cys-C、β2-MG、UA、RDW水平在系统性红斑狼疮患者中明显高于对照组,而RBC、HB、C3、C4、A/G则明显低于对照组。尿蛋白阳性的系统性红斑狼疮患者IgG、IgA、C3、A/G、RBC、HB水平显著低于尿蛋白阴性患者,而Cys-C、β2-MG、UA ...
胥兴丽, 王仁峰
doaj
Lenalidomideas a Second-line Therapy Achieves Long-term Remission in Elderly Patients with Relapsed/Refractory Multicentric Castleman's Disease：a Report of Two Cases and Literature Review [PDF]
, 2022 No standard therapy is recommended for elderly multicentric Castleman's disease (MCD) patients who failed to the first-line treatment or relapsed. Lenalidomide has been reported to be effective for relapsed/refractory MCD in foreign countries, but ...
TANG Yangming, SHI Renzhou, LAN Mei, LI Xuejun, WEN Zonghua, LU Xiaochen
core +1 more source
, 2020 【目的】探讨系统性红斑狼疮（SLE）合并妊娠孕妇孕期病情变化以及对妊娠结局的影响，分析不良妊娠结局的相关危险因素。【方法】回顾性分析2013年1月1日至2018年12月31日在中山大学附属第三医院产检并分娩，且病例资料完整的合并SLE孕妇，共89例孕妇，95次妊娠，分析孕期SLE病情活动情况及妊娠结局，找出不良妊娠结局的相关危险因素。【结果】①根据SLE疾病活动指数（SLEDAI）评价病情变化，将其分为疾病活动组及稳定组，其中孕期出现病情活动39例（活动组，A组），病情稳定56例（稳定组，B组 ...
孟召然 +4 more
core
Zhongguo shiyan zhenduanxue, 2020 系统性红斑狼疮（SLE）是自身免疫介导的弥漫性结缔组织病,以免疫性炎症为突出表现。老年系统性红斑狼疮是指≥50岁初发的SLE,较少见,约占系统性红斑狼疮患者的6.8%-18%[1-3]。老年人群本身机能退化等特点使老年SLE患者起病时临床症状轻,临床表现不典型,病情较为隐匿,关节痛和关节炎仍是最常见的临床表现 ...
黄丹, 南鹤
doaj
Establishment and evaluation of nomogram for differential diagnosis of systemic lupus erythematosus based on laboratory indications [PDF]
Objective·To establish a nomogram for the differential diagnosis of early systemic lupus erythematosus (SLE) and other autoimmune diseases based on laboratory indications, and to evaluate its efficacy.Methods·A total of 535 SLE patients admitted to the ...
CHEN Liubao +4 more
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Recent Developments in Stem Cells from Human Exfoliated Deciduous Teeth in the Treatment of Non-oral Diseases [PDF]
, 2023 Stem cells from human exfoliated deciduous teeth (SHEDs) are odontogenic stem cells with strong proliferation ability and multilineage differentiation potential.
JIANG Zhihan, XU Ling
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Systemic lupus erythematosus complicated with pure red cell aplasia: a case report and literature review [PDF]
This article reports a single case of a patient with systemic lupus erythematosus (SLE) combined with pure red cell aplasia (PRCA), and reviews 51 additional cases of patients reported by domestic and overseas papers from 1974 to 2021.
CHEN Qiong, FANG Jie, WEI Qianghua
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