系统性红斑狼疮 - Open Access .click

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Zhongguo shiyan zhenduanxue, 2006
目的目的观察有丝分裂原激活的蛋白激酶-细胞外调节激酶（MAPKERK1/2）细胞信号通路在系统性红斑狼疮（SLE）并肾炎（LN）患者外周血单个核细胞（PBMC）活化状态,探讨MAPKERK1/2通路在LN患者免疫异常中的作用及临床意义。方法26例LN患者和21例正常健康对照者进入研究,取外周血分离PBMC进行体外培养,利用蛋白印迹法（Western Blot）测定PBMC MAPKERK1/2蛋白磷酸化活化水平,比较LN与正常对照PBMC MAPKERK1/2活化水平的差异,并分析MAPKERK1 ...
张涤华 +6 more
doaj

[A multicenter study on the tolerance of intravenous low-dose cyclophosphamide in systemic lupus erythematosus]. [PDF]

Beijing Da Xue Xue Bao Yi Xue Ban, 2022
Shao M +16 more
europepmc +1 more source

谷氨酰半胱氨酸连接酶活性在系统性红斑狼疮中的变化及意义

Zhongguo shiyan zhenduanxue, 2014
目的探讨SLE人群和正常对照组外周血淋巴细胞中谷氨酰半胱氨酸连接酶（GCL）活性的差异。方法收集30例活动期的SLE病例与30名正常对照,利用密度梯度离心法提取外周血淋巴细胞,酶法测定外周血淋巴细胞中GCL的活性水平。同时分析合并和未合并狼疮肾炎的SLE组之间GCL活性水平的差异。结果与对照组（383.27±18.68mmol/min/mg蛋白浓度）相比较,SLE组（266.10±13.31mmol/min/mg蛋白浓度）GCL活性水平明显下降 ...
原江水, 张宗亮, 宋卫青
doaj

Systemic lupus erythematosus and antiphospholipid antibody syndrome associated Addison disease: A case report. [PDF]

Zhong Nan Da Xue Xue Bao Yi Xue Ban, 2021
Li Z, Peng Y, Zhang W, Xie Y.
europepmc +1 more source

γδ-TCR阳性T细胞与SLE关联性的初步研究

Zhongguo shiyan zhenduanxue, 1997
γδ－ＴＣＲ阳性Ｔ细胞与ＳＬＥ关联性的初步研究王树军张冬青马安伦王颖周昕顾越英周光炎系统性红斑狼疮（ＳＬＥ）是多器官受累，涉及体液及细胞免疫功能异常的自身免疫病，机理十分复杂。先前的工作已经发现ＳＬＥ患者除了出现多种自身抗体和自身反应性Ｔ细胞，其ＣＤ...
doaj

[Relationship of serum 25- hydroxy vitamin D and systemic lupus erythematosus]. [PDF]

Beijing Da Xue Xue Bao Yi Xue Ban, 2021
Zou JM, Wu LJ, Luo CN, Shi YM, Wu X.
europepmc +1 more source

[Systemic lupus erythematosus complicated by autoimmune nodopathy: A case report]. [PDF]

Beijing Da Xue Xue Bao Yi Xue Ban
Wei C, Yang Y, Zhao X, Liu X, Jia Y.
europepmc +1 more source

[Impact of aspirin use on pregnancy outcomes in patients with systemic lupus erythematosus]. [PDF]

Beijing Da Xue Xue Bao Yi Xue Ban
Li X, Zhao J, Mu R.
europepmc +1 more source

Identification and functional analysis of a novel phospholipase D2 gene mutation associated with familial systemic lupus erythematosus. [PDF]

Zhong Nan Da Xue Xue Bao Yi Xue Ban, 2021
Peng L, Yuan X, Chen L, Chen S, Chen K.
europepmc +1 more source

[Predictors of adverse pregnancy outcomes in patients with systemic lupus erythematosus]. [PDF]

Beijing Da Xue Xue Bao Yi Xue Ban
Wang W, Hou Y, Li C, Zhang X.
europepmc +1 more source

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