紫云英苷抑制APP/PS1小鼠大脑皮质神经元凋亡 [PDF]
目的探讨紫云英苷 (AST)对APP/PS1转基因小鼠大脑皮质神经元凋亡的影响。方法将18只6月龄雄性APP/PS1转基因小鼠随机分为APP/PS1、APP/PS1+40 mg/kg AST、APP/PS1+20 mg/kg DNP (Donepezil, DNP)三组,每组各6只动物。同时另选6只同月龄C57BL/6雄性小鼠作为正常对照组 (Control)。腹腔注射给药AST,每日一次,连续给药一个月后,Tunel染色法检测APP/PS1小鼠大脑皮质内神经元凋亡情况;免疫荧光染色法检测APP ...
王姝涵 +7 more
doaj +3 more sources
紫云英苷诱导自噬减轻APP/PS1转基因小鼠皮质内神经元损伤及老年斑沉积 [PDF]
目的探讨紫云英苷(AST)对APP/PS1转基因小鼠脑皮质神经元及Aβ斑块的影响。方法将24只8月龄雄性APP/PS1转基因小鼠随机分为APP/PS1组、10 mg/kg AST(APP/PS1+AST 10)组、20 mg/kg AST(APP/PS1+AST 20)组、40 mg/kg AST(APP/PS1+AST 40)组,每组各6只。6只同月龄C57BL/6雄性小鼠作为对照组(WT组)。AST药物连续腹腔注射一个月后,采用免疫荧光染色法观察小鼠脑皮质内Aβ斑块沉积情况 ...
杨翠珠 +6 more
doaj +3 more sources
Dual-directional Regulation of Tea Polyphenols on the Growth of Lactobacillus plantarum, Staphylococcus aureus, and Escherichia coli [PDF]
Enhancing the vitality of probiotics in probiotic product while inhibiting the growth of food-borne pathogenic and spoilage bacteria can improve product quality stability.
Fulin JIANG, Qiang HE, Yunhao LU
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Simultaneous Determination of Nine Chlorogenic Acids and Flavonoids in Mori Folium by QAMS [PDF]
Objective: To establish a HPLC method for the determination of neochlorogenic acid, chlorogenic acid, cryptochlorogenic acid, rutin, isoquercitrin, isochlorogenic acid B, astragalin, isochlorogenic acid A and isochlorogenic acid C in Mori Folium using ...
AYINUER·Baikere +5 more
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Extraction of active ingredients from Penthorum chinense pursh and comparison of component distribution in different parts [PDF]
Objective: This study aimed to determine the extraction solvent and compare the distribution of functional ingredient and antioxidant activities in different parts of Penthorum chinense pursh. Methods: the total phenolic content, total flavonoid content,
CHEN Song +4 more
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Comparison of Active Components, Antioxidant Activity and Pancreatic Lipase Inhibitory Activity in Different Solvent Extracts of Penthorum chinense Leaves [PDF]
The Penthorum chinense Pursh leaves were rich in active ingredients. The active ingredient content, in vitro antioxidant capacity and pancreatic lipase inhibition ability of P. chinense leaves extracted by different solvents (80% acetone, 80% ethanol, 80%
Boyu ZHU +6 more
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Composition of Free and Bound Phenolics from Paeonia suffruticosa Andr. Flowers and Their Antioxidant and α-Glucosidase inhibitory Activities [PDF]
Free phenolics (FP), esterified phenolics (EP), glycosidized phenolics (GP) and insoluble bound phenolics (IBP) were successively extracted from two varieties of peony flowers: Danfeng and Xiangyu.
CHEN Ling, WANG Xuefang, LI Zhining, ZHANG Lipan, LI Xiao, NING Erjuan
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Influence of Pile Fermentation Time on the Sensory Flavor and Non-volatile Compounds of Yixian Dark Tea [PDF]
In order to investigate the key nodes affecting the changes of Yixian dark tea flavor and quality during the Pile fermentation, in this study, the sensory quality and non-volatile profiles of Yixian dark tea samples at different pile fermentation periods
Hanchen ZHOU +6 more
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Identification of Polyphenolic Components in Unripe Banana Pulp and Their Inhibitory Effects on α-Amylase and α-Glucosidase [PDF]
The composition of phenolics extracted from unripe banana flesh was identified using ultra-high performance liquid chromatography coupled with Q-Exactive Orbitrap mass spectrometry (UPLC-Q-Exactive Orbitrap-MS), and the inhibitory effects of banana ...
WANG Qian, WANG Juan, FU Jinfeng, SHENG Ou
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Non-targeted Metabolomics Analysis of Key Characteristic Components in Liudong Tea [PDF]
This study employed non-targeted metabolomics combined with chemometrics to investigate the effects of different manufacturing processes, harvest times and cultivation methods on the key characteristic components of Liudong tea, a specialty tea cultivar ...
ZHAO Jie, LI Furong, LIU Wenwen, MA Jiangming, QIN Jiashuang, CHEN Yan, WANG Xu
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