Results 1 to 10 of about 85 (78)

紫云英苷抑制APP/PS1小鼠大脑皮质神经元凋亡 [PDF]

Zhongshan Daxue xuebao. Yixue kexue ban, 2023
目的探讨紫云英苷 （AST）对APP/PS1转基因小鼠大脑皮质神经元凋亡的影响。方法将18只6月龄雄性APP/PS1转基因小鼠随机分为APP/PS1、APP/PS1+40 mg/kg AST、APP/PS1+20 mg/kg DNP （Donepezil， DNP）三组，每组各6只动物。同时另选6只同月龄C57BL/6雄性小鼠作为正常对照组 （Control）。腹腔注射给药AST，每日一次，连续给药一个月后，Tunel染色法检测APP/PS1小鼠大脑皮质内神经元凋亡情况；免疫荧光染色法检测APP ...
王姝涵, 杨翠珠, 张润恒, 林佳泓, 杨雅琪, 刘靖, 李国营, 马宇昕   +7 more
doaj   +3 more sources

紫云英苷诱导自噬减轻APP/PS1转基因小鼠皮质内神经元损伤及老年斑沉积 [PDF]

Zhongshan Daxue xuebao. Yixue kexue ban, 2022
目的探讨紫云英苷（AST）对APP/PS1转基因小鼠脑皮质神经元及Aβ斑块的影响。方法将24只8月龄雄性APP/PS1转基因小鼠随机分为APP/PS1组、10 mg/kg AST（APP/PS1+AST 10）组、20 mg/kg AST（APP/PS1+AST 20）组、40 mg/kg AST（APP/PS1+AST 40）组，每组各6只。6只同月龄C57BL/6雄性小鼠作为对照组（WT组）。AST药物连续腹腔注射一个月后，采用免疫荧光染色法观察小鼠脑皮质内Aβ斑块沉积情况 ...
杨翠珠, 张润恒, 王姝涵, 蒋裕芸, 刘靖, 李国营, 马宇昕   +6 more
doaj   +3 more sources

紫云英苷调控炎性痛模型小鼠L_4-5脊髓背角星形胶质细胞自噬与凋亡

Zhongshan Daxue xuebao. Yixue kexue ban
目的探究紫云英苷（AST）对完全弗氏佐剂（CFA）诱发的炎性痛小鼠L4-5脊髓背角星形胶质细胞自噬及凋亡的影响。方法将24只雄性6月龄C57BL/6小鼠随机分为正常组（control）、生理盐水组（saline）、CFA模型组、CFA+AST组，每组6只小鼠。于小鼠右侧腓骨外踝窝注射10 µL CFA建立炎性痛小鼠模型。saline组小鼠注射等量生理盐水。CFA+AST组小鼠在疼痛造模成功后腹腔注射给药60 mg/kg AST，每日一次，连续给药21 d。采用多重免疫荧光染色法检测各组小鼠L4 ...
张维珊, 林佳泓, 王灿, 张润恒, 杨俊华, 刘靖, 李国营, 马宇昕   +7 more
doaj  

[Synergistic effect of azacitidine with homoharringtonine by activating the c-MYC/DDIT3/PUMA axis in acute myeloid leukemia]. [PDF]

Zhonghua Xue Ye Xue Za Zhi, 2023
Li J, Huang YQ, Zi J, Song CH, Ge Z.
europepmc   +1 more source

[Chinese guideline for diagnosis and management of drug-induced liver injury (2023 version)]. [PDF]

Zhonghua Gan Zang Bing Za Zhi, 2023
Technology Committee on DILI Prevention and Management, Chinese Medical Biotechnology Association;, Study Group of Drug-Induced Liver Disease, Chinese Medical Association for the Study of Liver Diseases.   +3 more
europepmc   +1 more source

Effects of isoprenylcysteine carboxylmethyltransferase silencing on the migration and invasion of tongue squamous cell carcinoma. [PDF]

Hua Xi Kou Qiang Yi Xue Za Zhi, 2021
Zhou N, Chi ZP, Li WJ, Zhao K, Wang SR, Wang QM, Tong L, He ZX, Han HY, Wang Y, Chen ZG.   +10 more
europepmc   +1 more source

[Analysis of chemical components of Chinese medicine Ligustici Radix by achiral-chiral liquid chromatography-predictive multiple reaction monitoring]. [PDF]

Se Pu, 2021
Xu X, Li T, Jia J, Tang H, Li J, Zhao Y, Song Y.   +6 more
europepmc   +1 more source

Asiatic acid improves insulin secretion of β cells in type 2 diabetes through TNF-α/Mfn2 pathway. [PDF]

Zhejiang Da Xue Xue Bao Yi Xue Ban, 2023
Li L, Wang W, Xu Q, Huang M.
europepmc   +1 more source

Clinical effect of different maintenance doses of caffeine citrate in the treatment of preterm infants requiring assisted ventilation: a pilot multicenter study. [PDF]

Zhongguo Dang Dai Er Ke Za Zhi, 2022
Yang Y, Lu KY, Cheng R, Zhou Q, Fang GD, Li H, Shao J, Wang HY, Li ZY, Liu SL, Li ZG, Cai JL, Xue M, Chen XQ, Pan ZJ, Gao Y, Huang L, Li HY, Song L, Wang SN, Shu GH, Wu W, Yu MZ, Xu Z, Li HX, Xu Y, Bao ZD, Wu XP, Ye L, Dong XP, Yin QG, Yin XP, Zhou JJ, Jiangsu Premature Infant Respiratory Failure Cooperation.   +33 more
europepmc   +1 more source

[Guidelines on the management of cholestasis liver diseases (2021)]. [PDF]

Zhonghua Gan Zang Bing Za Zhi, 2022
Chinese Society of Hepatology, Chinese Medical Association.   +1 more
europepmc   +1 more source