Results 21 to 30 of about 11,964 (159)
Role of P97 in non-transferrin bound iron uptake by rabbit reticulocytes [PDF]
, 2017 2000-2001 > Academic research: refereed > Publication in refereed journalVersion of ...
Chen, WF, Qian, ZM
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Rare Metals, Volume 45, Issue 2, February 2026.ABSTRACT The limited osteogenic capacity of magnesium phosphate cement (MPC) has constrained its biomedical applications, underscoring the necessity to develop MPC with enhanced physical properties and bone‐forming capabilities. In this study, a multifunctional MPC system was developed by incorporating zoledronic acid‐loaded near‐infrared (NIR ...
Bin Wang +8 more
wiley +1 more source
Engineering the Plasmodium berghei genome via CRISPR/Cas9 system [PDF]
, 2015 疟疾是由雌性按蚊叮咬而感染疟原虫所引起的虫媒传染病。2013年全球因感染疟疾而死亡的人数达58万，是世界公共卫生的沉重负担，主要易感人群是撒哈拉沙漠以南非洲地区5岁以下免疫力低下的儿童。其中感染恶性疟原虫引起的重症脑型疟最为严重且致死率极高。啮齿动物疟原虫是研究疟原虫与宿主互作的良好模型，伯氏疟原虫ANKA株系（PlasmodiumbergheiANKA）感染小鼠能够产生实验型脑疟症状，已广泛用于恶性疟原虫的致病机理研究。虽然疟原虫的转染技术有二十年的历史了，但由于缺乏高效的基因修饰工具 ...
肖波
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Rare Metals, Volume 45, Issue 1, January 2026.ABSTRACT Nanozymes have attracted considerable attention in cancer therapy due to their adjustable enzyme activity and high catalytic efficiency. However, they still face a major challenge from tumor metastasis. In this work, endogenous/exogenous dual‐responsive bimetallic hollow PdRu (termed HPdRu) nanozymes were prepared.
Nan‐Nan Zheng, Xin Hu, Jun‐Qing Hu
wiley +1 more source
Zhongshan Daxue xuebao. Yixue kexue ban, 2022 目的既往有研究表明，输注较长时间储存的红细胞可能使疾病的预后变差，尤其是创伤、重症和接受心脏手术的病人。为了探讨在肿瘤病人当中，输注红细胞的储存时间对肿瘤病人的远期预后是否有影响，本回顾性研究分析了术中输注红细胞对肝细胞癌切除术后病人的复发及总生存率的影响。方法本研究收集了2008年8月1日至2012年6月30日于中山大学肿瘤防治中心（中国，广州）接受肝细胞癌切除术的病人1221例，分为输血组与未输血组，其中输血组根据输注红细胞的储存时间进一步分为新鲜红细胞组（储存时间≤14 d）和陈旧红细胞组 ...
薛瑞峰 +6 more
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Systematic Analysis of ApiAP2 Transcription Factor Gene Family in the Rodent Malaria Parasite Plasmodium yoelii [PDF]
, 2016 疟疾是疟原虫（Plasmodiumspp.）感染导致的蚊媒传染性疾病，疟原虫生活周期复杂，经历了多宿主和多细胞形态的转化，每一步都需要精确地基因时空表达调控，转录因子介导的DNA转录水平的调控起到重要作用。 ApiAP2基因家族是疟原虫基因组中预测的为数极少的转录因子基因家族，在人疟原虫和啮齿类动物疟原虫中高度保守。在顶复体亚门生物（包括疟原虫）和植物中，ApiAP2基因编码蛋白均含有一个或者多个60个氨基酸大小的AP2DNA结合结构域，起到激活或抑制转录的作用。 之前的转录谱和蛋白质组学分析发现 ...
赵伊华
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Boron Difluoride Chelated Aminoanthraquinone Photosensitizer for Type I Photodynamic Therapy
Rare Metals, Volume 45, Issue 1, January 2026.ABSTRACT Type I photosensitizers capable of generating cytotoxic reactive oxygen species (ROS), with reduced oxygen dependence under photoirradiation, are regarded as a promising phototherapeutic approach for hypoxic solid tumors. Herein, based on the electron donor of 9‐phenyl‐carbazole (Cz) and the electron acceptor of anthraquinone (AQ ...
Tian Zhang +8 more
wiley +1 more source
Revisions to the Classification, Nomenclature, and Diversity of Eukaryotes
Journal of Eukaryotic Microbiology, Volume 66, Issue 1, Page 4-119, January/February 2019., 2019 Abstract This revision of the classification of eukaryotes follows that of Adl et al., 2012 [J. Euk. Microbiol. 59(5)] and retains an emphasis on protists. Changes since have improved the resolution of many nodes in phylogenetic analyses. For some clades even families are being clearly resolved.
Sina M. Adl +46 more
wiley +1 more source
Gene structure analysis and differentially splicing between Plasmodium yoelii subspecies [PDF]
, 2016 啮齿类动物约氏疟原虫（Plasmodiumyoelii）是研究宿主-寄生虫相互关系和疟原虫病理分子基础的一种重要的动物模型。尽管约氏疟原虫YM虫株的基本基因组信息已被测定，在最近也有许多啮齿类动物疟原虫的RNA-seq序列信息已见报道，但不同疟原虫品系或者亚种之间可能存在基因编码区及mRNA转录结构上的差异。构建多种疟原虫品系和亚种的cDNA文库将有助于我们对疟原虫遗传模式和转录组结构的认识。 本研究，我们用约氏疟原虫NSM虫株有或无MQ药物压力的红内期原虫样本构建了两个cDNA文库并对其进行深度测序 ...
刘建文
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Veterinary Dermatology, Volume 36, Issue 5, Page 668-678, October 2025.Background – Erythemato‐ceruminous otitis externa (ECOE) is commonly associated with Malassezia spp. and microbial imbalance. Hypothesis/Objective – To assess the clinical performance of an ear cleaner in dogs suffering from ECOE associated with Malassezia spp. overgrowth and to measure its impact on the microbiota. Conclusions and Clinical Relevance –
Amaury Briand +11 more
wiley +1 more source