Results 11 to 20 of about 71,292 (142)

肝移植围术期纤溶酶活性及α2-抗纤溶酶活性变化 [PDF]

open access: yesZhongshan Daxue xuebao. Yixue kexue ban, 2006
【目的】观察肝移植围术期纤溶酶活性及α2-抗纤溶酶活性的变化。【方法】19例患者分为重型肝炎组(H组,8例)与肝肿瘤组(N组,11例),接受原位肝移植术,均未采用体外静脉-静脉转流。两组患者分别于术前(T0)、手术1h(T1)、无肝10min(T2)、新肝5min(T3)、关腹前30min(T4),5个时间点,抽取动脉血测定纤溶酶活性及α2-抗纤溶酶活性,并记录各时段促凝抗纤溶药物的用量。【结果】两组患者纤溶酶活性在T2、T3和T4与T0比较明显增强(P〈0.05);α2-抗纤溶酶活性在T1 ...
甘小亮   +5 more
doaj   +1 more source

Increased glutamate in type 2 diabetes in the Korean population is associated with increased plasminogen levels. [PDF]

open access: yesJ Diabetes, 2023
Highlights Increased glutamate is associated with the development of diabetes. Glutamate increases plasminogen (PLG) levels through glutamate metabotropic receptor 5 activation with various insulin resistance‐related stresses. Glutamate inhibits the conversion of PLG to plasmin by increasing plasminogen activator inhibitor‐1.
Lee HJ   +7 more
europepmc   +2 more sources

尖吻蝮蛇蛇毒纤溶因子单克隆抗体的制备 [PDF]

open access: yesZhongshan Daxue xuebao. Yixue kexue ban, 1999
目的: 制备从尖吻蝮蛇蛇毒中分离的纤溶因子的单克隆抗体, 为克隆基因提供特异性的探针。方法: 将纤溶因 子免疫 Balb/C 小鼠,取脾细胞与 SP 2/0 骨髓瘤细胞融合, 筛选稳定分泌抗体的细胞株。采用血纤维蛋白平板法,观察单克隆 抗体能否抑制纤溶因子的纤溶作用。结果: 获得 2 株稳定分泌单克隆抗体的细胞株。 Western 印迹显示该单克隆抗体能特异 地与纤溶因子结合,与其它蛋白无交叉反应, 此外,这 2株单克隆抗体具有抑制纤溶因子溶解人血纤维蛋白的作用。结论: 这 2 ...
邱鹏新 黎明涛 苏兴文 陈家树 颜光美
doaj   +1 more source

纤溶酶产生菌的诱变育种及其发酵条件的研究

open access: yes四川大学学报. 自然科学版, 2000
对纤溶酶产生菌B .L .PY进行了紫外线与亚硝基胍复合诱变 ,选育到突变株B .L .PYUM ,其纤溶酶产量较出发菌株提高了 2 7.2 % .通过正交分析法进一步优化了该突变株的发酵条件为 (% ) :食用蔗糖 3,玉米粉 1.1,酵母膏 0 .2 ,MgSO4 ·7H2 O 0 .0 9,CaCl2 0 .0 2 ,K2 HPO4 0 .1,pH7.2 ,通气量为 1∶0 .5~ 1∶1,转速为 4 50r/min ,37℃下发酵 4d ,其纤溶酶产量为 1140U/mL ,较出发菌株提高 4 ...
彭勇   +4 more
doaj   +1 more source

缅甸蝰蛇毒纤溶酶FⅡaa的分离及生物活性 [PDF]

open access: yesZhongshan Daxue xuebao. Yixue kexue ban, 2010
【目的】 从缅甸蝰蛇毒中分离纯化得到纤溶酶FⅡaa并研究其纤维蛋白溶解活性65377;【方法】 缅甸蝰蛇蛇毒纤溶酶FⅡaa经过离子交换层析和凝胶层析分离程序得到,SDS-PAGE电泳测得其分子质量,用纤维蛋白平板法测得其纤维蛋白溶解活性,SDS-PAGE电泳测得其纤维蛋白原和纤维蛋白水解特异性65377;通过小鼠背部皮下注射FⅡaa 测定FⅡaa的局部出血活性65377;取昆明种小白鼠42只,体质量(20 ± 2)g,雌雄各半,随机分成7组,每组6只,皮下注射0.1 mL的FⅡaa(5个剂量组 ...
doaj   +1 more source

细菌纤维素在氢氧化钠-尿素水溶液体系中的溶解性能研究

open access: yes, 2015
纤维素经过活化、再生后可以溶解在氢氧化钠/尿素体系中。本文研究了乙二胺活化对细菌纤维素结晶度的影响规律,得到最佳活化条件;然后将活化后的细菌纤维素在LiCl/DMAc体系中溶解再生,得到再生细菌纤维素。最后,使用氢氧化钠/尿素溶液作为再生细菌纤维素的复合溶剂,得到的细菌纤维素的水溶液。通过红外光谱、X射线衍射仪、热重分析仪等分析了细菌纤维素不同处理阶段得到产物的性能。溶解与再生并没有发生化学变化,纤维素的结构基本保持不变,但结晶度有所降低 ...
王璨   +5 more
core   +5 more sources

Study on Physicochemical, Structural and Emulsifying Properties of Insoluble Dietary Fiber of Cyperus esculentus(油莎豆不溶性膳食纤维理化性质、结构特征和乳化特性研究) [PDF]

open access: yesShipin kexue jishu xuebao
Cyperus esculentus is a high-quality and healthy crop, rich in nutrients. Insoluble dietary fiber of Cyperus esculentus was prepared via an enzymolysis method.
WANG Lingyu(王玲玉)   +11 more
doaj   +1 more source

Microwave‐Actuated CuS/CuCo2O4 Heterojunction Microneedles for Synergistic Eradication of Deep‐Seated Biofilms and Inflammatory Microenvironment Remodeling in Acne Treatment

open access: yesRare Metals, Volume 45, Issue 7, July 2026.
ABSTRACT Deep skin infections and dense biofilm barriers caused by Propionibacterium acnes (P. acnes) remain significant challenges in recurrent acne vulgaris, exacerbated by the poor stratum corneum penetration of conventional therapies and rising antibiotic resistance.
Bingran Qi   +3 more
wiley   +1 more source

Conversion of anionic derivatives of fermented cellulose and evaluation of their antifungal effect(发酵纤维素阴离子衍生物的转化与抗菌应用评价)

open access: yesZhejiang Daxue xuebao. Lixue ban, 2023
在水相条件下用阴离子醚化剂(3-氯-2-羟基丙磺酸钠)通过一锅法对经微生物改造的纤维素阴离子化,其中的氢氧化钠溶液既作为反应物、溶剂,又作为催化剂,反应条件温和、取代度适中、转化率较高。采用元素分析、核磁共振、傅里叶红外光谱等表征方法研究了纤维素衍生物的取代度和结构,结果表明,获得的纤维素产物已阴离子化。对纤维素衍生物进行了抑制真菌评估,证明其具其有一定的抑菌特性。纤维素衍生物的生态亲和性决定其可应用于文物保护、农业和防疫等领域。
崔艳丽(CUI Yanli)   +5 more
doaj   +1 more source

Encapsulation of Bi2S3 Within Multifunctional Sulfurized Polyacrylonitrile Matrix Enables High‐Performance Wide‐Temperature Sodium/Potassium‐Ion Batteries Through Solid–Solid Conversion

open access: yesRare Metals, Volume 45, Issue 6, June 2026.
ABSTRACT With high theoretical capacity and low cost, bismuth sulfide (Bi2S3) demonstrates considerable potential as an anode for sodium/potassium‐ion batteries (SIBs/PIBs). Unfortunately, significant volume variation, low electrical conductivity, and dissolution of polysulfides drastically weaken their intrinsic merits.
Fuyu Xiao   +11 more
wiley   +1 more source

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