Results 11 to 20 of about 4,491 (131)

Equine allergic skin diseases: Clinical consensus guidelines of the World Association for Veterinary Dermatology

open access: yesVeterinary Dermatology, Volume 34, Issue 3, Page 175-208, June 2023., 2023
Abstract Background Allergic skin diseases are common in horses worldwide. The most common causes are insect bites and environmental allergens. Objectives To review the current literature and provide consensus on pathogenesis, diagnosis, treatment and prevention. Materials and Methods The authors reviewed the literature up to November 2022.
R. Marsella   +6 more
wiley   +1 more source

Ceramide changes in abdominal subcutaneous and visceral adipose tissue among diabetic and nondiabetic patients 糖尿病和非糖尿病患者腹部皮下和内脏脂肪组织神经酰胺的变化

open access: yesJournal of Diabetes, Volume 14, Issue 4, Page 271-281, April 2022., 2022
Highlights The gender‐specific role of sphingolipids in obesity‐related metabolic dysfunctions is unclear. The aim of this study is to identify ceramide species by liquid chromatography‐mass spectrometry that accumulate in central fat in relation to status of diabetes and gender for subjects with a body mass index ≥40 kg/m2 or > 35 kg/m2 with ...
Michelle Brusatori   +7 more
wiley   +1 more source

Clinical Effectiveness Studies on using kidney reinforcing, bone strengthening and channel dredging Method (KRBSCDM) to treat Cervical Spondylosis [PDF]

open access: yes, 2015
目的:本课题主要通过总结导师诊治颈椎病的临床经验,继承发扬导师学术思想和临床经验,为临床治疗本病提供新的治疗思路和方法,以求进一步提高疗效。 方法:通过搜集、观察导师运用补肾壮骨疏经通络法针刺处方治疗颈椎病的病例,进行纳入排除标准选定。采用随机分组单盲对照的实验方法,对所选病例进行临床试验研究。具体将所选病例随机分为治疗组和对照组,治疗组采用导师治疗颈椎病的补肾壮骨疏经通络法针刺处方,对照组采用王华、杜元灏主编《针灸学》中治疗颈椎病的针刺处方,以10次为一疗程,共治疗2个疗程。设计临床资料观察表 ...
施彬彬
core  

An Ultrasmall Strontium‐Loaded Polydopamine Nanoformulation for Near‐Infrared‐Enhanced Periodontitis Therapy via Photodynamic Gas‐Promoted Antibacterial and Bone Repair

open access: yesRare Metals, EarlyView.
ABSTRACT Periodontitis is a chronic infectious oral disease triggered by periodontopathogenic bacteria, resulting in the progressive inflammation and destruction of the tissues surrounding teeth. To achieve reprogramming of the infectious microenvironment for periodontitis therapy, a nanoformulation was proposed by loading polydopamine (PDA) with ...
Hao Liang   +14 more
wiley   +1 more source

超声雾化蒸馏水激发试验测定哮喘病人气道反应性 [PDF]

open access: yes, 1988
对40例哮喘病人及10例正常人作超声雾化蒸馏水激发试验。病人吸入递增剂量的蒸馏水,直至FEV1下降超过基础值20%或吸入剂量达30ml为止。37例哮喘病人吸入蒸馏水后气道阻力增高,FEV1下降20%时所吸入的蒸馏水量(PD20FEV1水)为0.5至29ml(9.68±8.53)。正常人无出现阳性反应。该试验有良好的可重复性,并与标准的组胺激发试验有良好的相关(R=0.9334 ...
陈升汶
core  

Studies on Reaction of Trifluoromethanesulfonic Anhydride Activated Secondary Amides with Enamines [PDF]

open access: yes, 2015
酰胺是一类常见的稳定性很高的有机化合物。由于酰胺的高稳定性,酰胺很难直接转化,通常需要活化后才能与各类亲核试剂反应。目前,用于酰胺活化反应中的碳亲核试剂主要为有机金属试剂,包括有机镁试剂、锌试剂、锂试剂、铈试剂等,而弱亲核性的烯胺与活化酰胺的反应却研究的比较少。 酮在有机合成中是一类极其重要的多用途的化合物,由于其显著的反应活性和多反应位点,酮可进行许多反应,包括经典的羟醛缩合(Aldol)反应、Wittig反应以及Michael加成反应等。酮也是很多天然产物和具有生物活性药物的官能团结构。因此 ...
刘永鹏
core  

非甾体抗炎药相关的消化性溃疡并发上消化道出血 [PDF]

open access: yes
Through discussion of 1 elderly case with multiple drug application of upper gastrointestinal bleeding (UGIB), we have summarized non-steroidal anti-inflammatory drugs (NSAIDs) are responsible for peptic ulcer bleeding, then discussed the relationship ...
Xu, Tao, Xue, Jian-bo, Zhang, Dong-hai
core   +2 more sources

组织胺对肠黏膜免疫屏障的调节作用

open access: yesZhongguo shiyan zhenduanxue, 2008
目的观察组织胺对肠黏膜免疫分泌的调节作用。方法从十二指肠灌注大肠杆菌制成单纯感染模型,从颈静脉插管放血加十二指肠灌注大肠杆菌制成失血感染模型。大鼠随机分为假手术组、单纯感染组、失血感染组和1×10-6mol/L浓度的组织胺对以上各组的干预组共6组。组织胺干预组分别用1×10-6mmol/L的组织胺对制成的模型大鼠进行肠内灌注。观察模型大鼠免疫球蛋白IgA分泌量。结果1×10-6mmol/L组织胺干预组肠道IgA分泌量较失血-感染组也明显增多 ...
郝彦开, 冯丽英, 王军民
doaj  

TGM2在肺癌中的表达及诊断意义

open access: yesZhongguo shiyan zhenduanxue, 2021
人组织谷氨酰胺转胺酶(TGM2)是一种具有转谷氨酰胺酶交联(TGase)、G蛋白信号转导和激酶活性的多功能酶,被认为在多种疾病中起作用。TGM2的mRNA通过选择性剪接进行调控,产生C端截短形式的TGM2,被预测具有独特的生化特性和生物学功能。本研究将生物信息学手段联合临床分析,基于Western blot方法及免疫组化法验证并观察蛋白TGM2在肺癌中的表达及诊断意义。
王晶莹, 刘洋, 刘启迪
doaj  

哌拉西林钠舒巴坦钠过敏诱发心力衰竭1例 [PDF]

open access: yes, 2018
一例80岁男性患者因慢性支气管炎、肺气肿给予哌拉西林钠舒巴坦钠静脉滴注抗感染治疗,静滴约5min后出现畏冷、寒战,气喘、呼吸困难,血压212/120mmHg,心率130次/min,停药,给予吸氧,急查血常规:超敏C反应蛋白126.50mg·L-1。予注射用甲泼尼龙琥珀酸钠、呋塞米注射液、吗啡注射液、去乙酰毛花苷注射液、硝酸甘油注射液等治疗,约45min后患者症状逐渐缓解,心率逐渐下降至110次/min左右,血压逐渐下降至140 ...
陈雨丹
core  

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