Results 121 to 130 of about 15,431 (198)
Zhongguo shiyan zhenduanxue, 2011 目的研究尼莫地平对不同浓度氧化低密度脂蛋白诱导的人血管内皮细胞凋亡的影响。方法在人脐静脉内皮细胞株ECV304培养基中加入不同浓度氧化低密度脂蛋白和尼莫地平（1.2μg/ml）,作用6-24 h。透射电镜观察内皮细胞ECV304的凋亡情况;流式细胞术（FCM）检测细胞凋亡率;用激光共聚焦显微镜检测钙离子浓度。结果不同浓度氧化低密度脂蛋白能明显诱导培养的内皮细胞发生凋亡,尼莫地平可显著降低氧化低密度脂蛋白诱导的内皮细胞凋亡率 ...
刘秀玲 +4 more
doaj
Zhongguo shiyan zhenduanxue, 2016 目的研究洛铂对人膀胱癌细胞的抑制作用,并揭示其可能的作用机制。方法体外常规培养人膀胱癌细胞株5637。利用MTT细胞增殖法检测洛铂的细胞毒性;采用Annexin V-FITC/PI凋亡试剂盒在流式细胞仪上检测癌细胞的凋亡程度;通过伤口愈合实验观察细胞的迁移;通过Transwell小室测定评估洛铂对5637细胞侵袭和迁移能力的影响;利用蛋白免疫印迹法检测细胞凋亡基因的表达。结果洛铂抑制人膀胱癌细胞并诱导其凋亡,下调膀胱癌5637细胞Survivin和Bcl-2的表达水平,上调其Bax和Caspase ...
王丰, 于倩, 王华
doaj
[Myrislignan Induces Apoptosis in Gastric Cancer Cell Line Through PI3K/AKT Signaling Pathway]. [PDF]
Sichuan Da Xue Xue Bao Yi Xue Ban, 2023 Zhou YJ, Pan YY, Yang LJ, Bie MJ.
europepmc +1 more source
Zhongshan Daxue xuebao. Yixue kexue ban, 2013 【目的】研究siRNA沉默白细胞介素-1受体相关激酶-4(IRAK-4)基因对人成骨样细胞株MG63凋亡及凋亡相关基因Bcl-2、Bax表达的影响。【方法】 以Lipofectamine 2000为载体将IRAK-4-siRNA转染入MG63细胞(CON组:不加入任何转染试剂;SC组:以scrambled siRNA序列进行转染;KD组:以特异性IRAK-4-siRNA序列进行转染),应用流式细胞术及TUNEL法检测细胞凋亡水平,western blotting检测Bcl-2、Bax基因的表达。【结果】
doaj
[Effect of pulsed electromagnetic fields on mesenchymal stem cell-derived exosomes in inhibiting chondrocyte apoptosis]. [PDF]
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi, 2023 Xu Y +6 more
europepmc +1 more source
[Role and mechanisms of FoxO3a-related signaling pathways in breast cancer cell apoptosis]. [PDF]
Zhong Nan Da Xue Xue Bao Yi Xue BanWang Z +5 more
europepmc +1 more source
[Mechanism of Trifolin in Attenuating Hypertension-Induced Renal Cell Apoptosis via Modulation of the MAPK Signaling Pathway]. [PDF]
Sichuan Da Xue Xue Bao Yi Xue BanWu M +8 more
europepmc +1 more source
Expression of PGRMC1 in patients with polycystic ovary syndrome and its molecular mechanism for regulating ovarian granulosa cell apoptosis and glucolipid metabolism. [PDF]
Zhong Nan Da Xue Xue Bao Yi Xue Ban, 2023 Zhou J +5 more
europepmc +1 more source