Results 51 to 60 of about 11,137 (150)
Expression of PGRMC1 in patients with polycystic ovary syndrome and its molecular mechanism for regulating ovarian granulosa cell apoptosis and glucolipid metabolism. [PDF]
Zhou J+5 more
europepmc +1 more source
[Effect of pulsed electromagnetic fields on mesenchymal stem cell-derived exosomes in inhibiting chondrocyte apoptosis]. [PDF]
Xu Y+6 more
europepmc +1 more source
【目的】观察槲皮素对急性髓系白血病HL-60 细胞凋亡与自噬的影响及腺苷酸活化蛋白激酶 (AMPK)活性的变化,探讨槲皮素抗白血病的分子机制。【方法】流式细胞仪、电镜、蛋白质印迹法检测槲皮素孵 育HL-60细胞24、48 h后细胞凋亡与自噬的水平;检测槲皮素作用后HL-60细胞AMPK、p-AMPK的表达;流式、 蛋白质印迹法检测不同浓度槲皮素与AMPK小分子抑制剂Compound C共同孵育HL-60细胞后AMPK活化的情 况及细胞凋亡、自噬的变化。【结果】槲皮素可诱导HL-60细胞发生凋亡 ...
肖洁+8 more
doaj
[High expression of MYH9 inhibits apoptosis of non-small cell lung cancer cells through activating the AKT/c-Myc pathway]. [PDF]
Liu F, Peng L, Xi J.
europepmc +1 more source
【目的】为探索XIAP 相关因子1( Xaf1) 调节肿瘤细胞凋亡的机制, 利用基因开关调节系统( Teton) , 拟建立由doxycycline 调控表达的Xaf1 诱导细胞株。【方法】将pTREHA-Xaf1 和pWZL-Hyg 质粒用基因 转染技术转入稳定表达rtTA 的Saos-2 细胞中。经过hygromycin 的抗性筛选, 挑出并扩增表达Xaf1 的细胞株。 在8 例实验组中加入doxycycline, 和不加doxycycline 的8 例对照组比较, 重复3 ...
夏焱+6 more
doaj
[Shikonin induces hepatocellular carcinoma cell apoptosis by suppressing PKM2/PHD3/HIF-1α signaling pathway]. [PDF]
Zhang H, Chen Z, Zhao X, Huo Q, Cheng X.
europepmc +1 more source