Results 21 to 30 of about 1,505,532 (176)

Cancellous Bone‐Like Sr‐Doped Hydroxyapatite/Gelatin Porous Scaffolds With Nanofibrous Architecture and Ion Release for Promoting Osteogenesis

open access: yesRare Metals, Volume 45, Issue 4, April 2026.
ABSTRACT Constructing a porous scaffold with the essential features of natural cancellous bone, including structural architecture and biochemical cues, is one of the pivotal factors for effective bone regeneration. In this study, a biomimetic composite porous Gelatin fibrous scaffold (SrHA/Gelatin) incorporating ultralong strontium‐doped hydroxyapatite
Yin‐Chuan Wang   +8 more
wiley   +1 more source

Elevation, soil pH and calcium availability shape regional and local scale spatial patterns of PhoD gene abundance in tropical and subtropical forests

open access: yesFunctional Ecology, Volume 40, Issue 4, Page 983-1000, April 2026.
Read the free Plain Language Summary for this article on the Journal blog. Abstract Organic phosphorus mineralization is a critical process in the phosphorus cycle, governing phosphorus bioavailability for plants. The PhoD gene, which encodes the key enzyme alkaline phosphatase, serves as a valuable biomarker for this process.
Sandhya Mishra   +3 more
wiley   +1 more source

结核多肽特异性细胞内因子多色流式分析

open access: yesZhongguo shiyan zhenduanxue, 2013
目的建立能同时检测CD3、CD4、CD8表型及胞内因子IFN-γ、IL-4、TNF-α的多色胞内细胞因子染色流式细胞术;评价六条结核特异性多肽的性能。方法将结核患者组及健康对照组的PBMC,用结核特异性多肽或PMA刺激培养后,通过胞内细胞因子流式检测术,收集荧光标记阳性的淋巴细胞等;从而确定各亚群IFN-γ、IL-4、TNF-α阳性细胞的数量及百分率,得出两组间及各多肽间的性能差异。结果 1.各多肽均能刺激活化结核患者PB-MC产生IFN-γ等细胞因子,但百分率较低;IFN-γ及IL-4多数小于1 ...
詹能勇   +7 more
doaj  

Multiple pregnancy with complete hydatidiform mole and coexisting normal fetus: systematic review and meta‐analysis of clinical outcomes from non‐randomized studies

open access: yesUltrasound in Obstetrics &Gynecology, Volume 67, Issue 3, Page 272-282, March 2026.
ABSTRACT Objective Complete hydatidiform mole and coexisting normal fetus (CHMCF) is a rare condition for which there is significant heterogeneity in diagnosis, counseling and management of complications. The objective of this study was to summarize the prevalence of clinical outcomes in reported cases of CHMCF.
N. Salmeri   +8 more
wiley   +1 more source

NIR‐Responsive Nano‐Integrated Magnesium Phosphate Cement Promotes Bone Regeneration via Osteoblast‐Exosome‐Osteoclast Crosstalk

open access: yesRare Metals, Volume 45, Issue 2, February 2026.
ABSTRACT The limited osteogenic capacity of magnesium phosphate cement (MPC) has constrained its biomedical applications, underscoring the necessity to develop MPC with enhanced physical properties and bone‐forming capabilities. In this study, a multifunctional MPC system was developed by incorporating zoledronic acid‐loaded near‐infrared (NIR ...
Bin Wang   +8 more
wiley   +1 more source

Cu‐Enhanced Medium‐Entropy TiZrCoCrMo Alloys: Balancing Superior Antibacterial and Osteogenic Properties for Orthopedic Implants

open access: yesRare Metals, Volume 45, Issue 2, February 2026.
ABSTRACT This study introduces novel nonequiatomic TiZrCoCrMoCux (x = 0, 5, 10; at%) medium‐entropy alloys (MEAx) tailored for orthopedic implants, synergistically combining the biocompatibility of Ti‐based alloys, the wear resistance of CoCrMo alloys, and the antibacterial/osteogenic attributes of Cu. The alloy's microstructure, mechanical properties,
Hang Yu   +9 more
wiley   +1 more source

Endogenous/Exogenous Dual‐Responsive Bimetallic Hollow Nanozyme for Photothermal/Nanocatalysis/Immune Synergistic Tumor Therapy

open access: yesRare Metals, Volume 45, Issue 1, January 2026.
ABSTRACT Nanozymes have attracted considerable attention in cancer therapy due to their adjustable enzyme activity and high catalytic efficiency. However, they still face a major challenge from tumor metastasis. In this work, endogenous/exogenous dual‐responsive bimetallic hollow PdRu (termed HPdRu) nanozymes were prepared.
Nan‐Nan Zheng, Xin Hu, Jun‐Qing Hu
wiley   +1 more source

Boron Difluoride Chelated Aminoanthraquinone Photosensitizer for Type I Photodynamic Therapy

open access: yesRare Metals, Volume 45, Issue 1, January 2026.
ABSTRACT Type I photosensitizers capable of generating cytotoxic reactive oxygen species (ROS), with reduced oxygen dependence under photoirradiation, are regarded as a promising phototherapeutic approach for hypoxic solid tumors. Herein, based on the electron donor of 9‐phenyl‐carbazole (Cz) and the electron acceptor of anthraquinone (AQ ...
Tian Zhang   +8 more
wiley   +1 more source

细菌必需基因、最小基因组和合成细胞

open access: yes, 2012
单细胞原核生物是原始的细胞生命形式,确定细菌必需基因和最小基因组对理解生命的本质、细胞生命的起源和进化有非常重要的意义。文中简要介绍近年来有关细菌的必需基因、最小基因组和合成细胞的研究方法、理论和进展 ...
邱东茹
core  

胰岛素样生长因子Ⅰ(IGF-Ⅰ)与各疾病的相关性研究进展

open access: yesZhongguo shiyan zhenduanxue, 2014
胰岛素样生长因子(IGFs)作为一类多功能细胞增殖调控因子,是一种在分子结构上与胰岛素类似的多肽蛋白物质,又称类胰岛素生长因子。其由两类物质组成,即IGF-Ⅰ和IGF-Ⅱ。在人体内,IGF-Ⅰ是胰岛素样生长因子的主要组成部分,除肝细胞是主要的分泌细胞外,肾细胞、脾细胞等多达十几种细胞均可分泌IGF-Ⅰ。IGF-Ⅰ在人体内受遗传、激素水平、营养状态等多方面影响 ...
吴淑会, 刘臣
doaj  

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