Results 1 to 10 of about 4,217 (131)
Successful surgical removal of a pheochromocytoma in a mare via trans‐costal approach
Equine Veterinary Journal, Volume 55, Issue 6, Page 1012-1020, November 2023., 2023 Abstract Background Pheochromocytomas have been previously reported in horses, but successful antemortem diagnosis and surgical removal without recurrence of clinical signs have not been described. Objective To report the clinical presentation, diagnostic evaluation, surgical technique, anaesthetic management and post‐operative care of a mare diagnosed
Thomas J. O'Brien +6 more
wiley +1 more source
Systematic review of shared decision‐making in guidelines about colorectal cancer screening
European Journal of Cancer Care, Volume 31, Issue 6, November 2022., 2022 Abstract Introduction We aimed to systematically evaluate quality of shared decision‐making (SDM) in colorectal cancer (CRC) screening clinical practice guidelines (CPGs) and consensus statements (CSs). Methods Search for CRC screening guidances was from 2010 to November 2021 in EMBASE, Web of Science, MEDLINE, Scopus and CDSR, and the World Wide Web ...
Marta Maes‐Carballo +6 more
wiley +1 more source
The Oncologist, Volume 24, Issue 11, Page 1416-1419, November 2019., 2019 Abstract Immune checkpoint blockade (ICB) is an approved therapy for advanced metastatic mismatch repair (MMR)‐deficient cancer regardless of tissue of origin. Although therapy is effective initially, recurrence rates are significant, and long‐term outcomes remain poor for most patients.
Arthur Winer +7 more
wiley +1 more source
Correlation of RELL1 Expression with Clinical Pathological Characteristics and Prognosis of Patients with Colon Cancer [PDF]
ObjectiveTo explore the correlation of RELL1 expression with clinical pathological features and prognosis of patients with colon cancer. MethodsImmunohistochemical experiments of the RELL1 protein were performed on tissue chips from 80 colon cancer ...
Jie FENG +5 more
core +1 more source
the effects and mechanisms of berberine on colitis and colon cancer [PDF]
, 2013 结肠癌是一种常见的消化系统恶性肿瘤，其发展过程非常缓慢，慢性感染和炎症反应已经成为结肠癌发生的重要危险因子。黄连素（Berberine），是从植物中提取出来的异喹啉生物碱，已被用来作为一种传统药物用于治疗细菌性腹泻和肠道寄生虫感染数十年。体外研究表明，黄连素不但具有抗炎症作用，还可通过调节信号转导来抑制炎性细胞因子的产生，并抑制多种肿瘤细胞的生长。在本课题中，我们首先观察黄连素对葡聚糖硫酸酯钠（DSS）诱导的结肠炎的作用。本研究结果显示，黄连素可改善DSS诱导的小鼠体重的减轻、结肠的缩短 ...
王立红
core
Study of Berberine’s Effect on the Apoptosis and Migration of Colon Cancer Cells [PDF]
, 2014 结肠癌是一种常见的消化道恶性肿瘤，严重威胁着人们的健康。结肠癌可以通过手术予以切除治疗，但治疗后多半会出现复发和转移，因此寻求到有效的抗癌药物成为结肠癌治疗的关键问题之一。黄连素（Berberine）又称小檗碱，是从黄连、黄柏等中药中提取的一种生物碱，临床上长期用于胃肠消化道疾病的治疗。研究发现，黄连素具有广泛的药理作用，近年来，它在抗肿瘤方面所具有的药理价值也逐渐被人们所关注和认可，且因其价格低廉、毒副作用小、药源丰富等优点而广受喜爱。研究证实，黄连素对多种肿瘤细胞都具有抑制作用 ...
陈彬彬
core
Expression of POSTN in acute colitis and colitis-associated cancer mice [PDF]
, 2013 炎症与多种肿瘤的发生发展密切相关，炎症性微环境的形成，是绝大多数癌症恶化的重要原因。包括炎症性肠病在内的多种形式的慢性炎症疾病，能够通过多种途径参与启始肿瘤发生。组织微环境中的细胞外基质将众多炎症相关事件联系在一起，且自身也参与到这些炎症相关事件当中。POSTN是一种分泌型细胞外基质蛋白，主要在胚胎组织如胚胎骨膜、心脏瓣膜、胎盘以及一些成体组织如骨和牙周韧带中高表达，并在一些成体组织损伤后呈现表达上调。目前已有研究表明POSTN在结肠癌组织中高表达并促进结肠癌肝转移 ...
阿来依.买提卡比力
core
Nursing Management of Radical Laparoscopic Left Colon Cancer Operation Extracted Specimen by Natural Orifice [PDF]
, 2016 目的探讨经自然腔道取标本的腹腔镜左结肠癌根治术治疗及护理管理。方法回顾性分析2014年1月—2015年6月该院29例采用自制套管器经肛门取标本的腹腔镜左结肠癌根治术患者临床资料。结果所有患者均顺利完成手术,术中无中转开腹、大出血、预防性末端回肠造瘘和复发病例。随访4~20个月,除1例术后24 d、72 d分别出现2次肠梗阻,经过保守治疗和护理管理后好转。结论采用自制套管器经肛门取标本的腹腔镜左结肠癌根治术安全可行,术中良好的护理管理实施对手术顺利进行具有关键作用。Objective To explore
曾学慧, 蔡建春, 许淑镇
core
Zhongguo shiyan zhenduanxue, 2009 目的在本研究中检测63例结直肠癌组织中CD44v6的表达情况,以评估CD44v6在结直肠肿瘤发生发展过程中的作用。方法采用HE染色,光镜,和免疫组化方法,观察不同病程阶段、不同病变范围的结直肠癌对细胞粘附分子CD44v6不同的表达情况。结果63例肿瘤组织标本中,对CD44v6表达有24例强阳性,13例阳性（中度染色）,26例阴性。CD44v6的阴性或阳性表达（中度染色）与肿瘤大小 ...
李滨 +4 more
doaj
Zhongguo shiyan zhenduanxue, 2022 神经内分泌肿瘤(Neuroendocrine neoplasia,NEN)是指起源于神经内分泌细胞和肽能神经元的肿瘤,可发生于全身各种组织和器官中,其中以胃肠胰神经细胞内分泌肿瘤(GEP-NEN)最常见。罕有发生于乙状结肠合并肝转移的病例报道。本文报道2021年4月25日吉林大学中日联谊医院胃肠结直肠外科收治的1例病例,初步诊断为乙状结肠腺癌合并肝转移。患者于同年4月29日行腹腔镜下乙状结肠癌根治术、肝脏转移病灶射频消融术。术后病理:乙状结肠肿物为混合性神经内分泌-非神经内分泌肿瘤 ...
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