Goodpasture syndrome complicated with lung infection: a case report and literature review [PDF]
, 2023 Objective To investigate the clinical characteristics， diagnosis and treatment of Goodpasture syndrome complicated with lung infection. Methods Clinical data of one case of Goodpasture syndrome complicated with pulmonary infection were retrospectively ...
Cen Tiantian, Zhang Xiaoqun, Ma Hongying
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The expression of p97 on the membrane of the reticulocyte and the role in iron uptake in rabbit [PDF]
, 2017 2001-2002 > Academic research: refereed > Publication in refereed journalVersion of ...
Chen, WF, Qian, ZM, Xie, JX
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Clinical Management and Genetic Features of 3 Cases of Shwachman-Diamond Syndrome [PDF]
, 2022 BackgroundShwachman-Diamond syndrome (SDS) is a rare autosomal recessive genetic disease that has complex and various clinical presentations. With the increase in application and clinical sensitivity of genome sequencing, the diagnoses of SDS in children
SUN Qing, XIE Yao, WU Penghui, LI Shuo, ZHAO Weihong
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Review and Perfection of Arbitration Procedure of Doping Cases in CAS： From the Perspective of the Establishment of ADD and Pechstein Case [PDF]
, 2017 佩希施泰因案侵犯了平等、正确、迅速、经济等仲裁制度的基本价值目标,引发各界对CAS兴奋剂案件仲裁程序合理性的担忧。虽然,目前并无其他纷争解决方式能够予以替代,但对仲裁程序进行改革已成为共识。CAS新设反兴奋剂部门被视为兴奋剂仲裁程序改革之起点,当前有必要突破原有路径束缚,重新建构仲裁程序以平衡运动员与对方当事人的利益关系,通过富有针对性的修正路径倒逼CAS仲裁体系的根本性变革。认为应以平等、正确、经济为兴奋剂案件仲裁程序的总体价值架构,认采部分普世法原则,同时辅以妥适的制度设计。具体而言 ...
刘韵
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Zhongguo shiyan zhenduanxue, 2023 目的 研究再生障碍性贫血(AA)病人外周血NK细胞及其受体表达的变化，探讨NK细胞在AA发病机制中的作用。方法 利用流式细胞术检测28例AA病人(其中SAA 9例，NSAA 19例)外周血NK细胞功能，包括NK细胞数量，活化性受体NKG2D,抑制性受体NKG2A,穿孔素，颗粒酶β的表达，T淋巴细胞亚群及与造血指标的相关性分析，另有18例健康志愿者为对照组。结果 AA病人外周血NK细胞数，NKG2D,颗粒酶表达减少，与对照组比较差异有统计学意义 ...
孔令环 +6 more
doaj
Role of P97 in non-transferrin bound iron uptake by rabbit reticulocytes [PDF]
, 2017 2000-2001 > Academic research: refereed > Publication in refereed journalVersion of ...
Chen, WF, Qian, ZM
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Characteristic analysis of human parvovirus B19 infection in patients with hematological disease [PDF]
ObjectiveTo explore the infection status and clinical characteristics of human parvovirus B19 (HPV-B19) in patients with hematological disease. MethodsA total of 94 patients with benign hematological disease, 128 patients with hematological malignancy ...
Lei WANG, Wei WEI, Yimin ZHAO
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Stuty on Interaction between Plasmodium yoelii and Recombinant Human Prothymosin α、S180 Tumor Cell [PDF]
, 2012 疟疾目前仍然是世界上严重危害人类健康的主要传染病之一，导致全球每年大约一百万人死亡。疟疾的发病机理非常复杂，人们对它的了解十分有限。疟原虫能够在宿主体内长期存在，很大一部分原因是疟原虫能干扰宿主的免疫反应和逃避宿主的免疫压力。 自1976年Trager和Jensen成功地对恶性疟原虫（Plasmodiumfalciparum）红内期体外连续培养获得成功后，该方法对疟原虫生化代谢及相关酶基因研究、疟疾化学治疗药物筛选、疟原虫抗药性检测、抗药基因特征研究等方面均产生了积极影响。至今 ...
王兵丽
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Factors affecting genetic crosses and mapping loci linked to sexual development and drug resistance phenotypes in Plasmodium yoelii [PDF]
, 2012 疟疾目前依然是非常严重的人类虫媒传染病。据世界卫生组织（WorldHealthOrganization，WHO）2010发布的报告，2009年约有78万人死于疟疾。疟疾持续存在并广泛流行的关键问题在于疟原虫对抗疟药物和蚊媒杀对虫剂的耐受性。同时由于我们对寄生虫与宿主反应及致病机理缺乏了解，也使得很多病人无法得到及时有效的救治。为了更好的研究疟疾的致病和抗药性的分子基础，我们建立了啮齿类疟原虫的动物模型。啮齿类疟原虫易于实验室传代保种，同时具备多种与人疟相类似的生物学表型（毒力和致死性、网织红细胞选择性 ...
朱锋
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一例补体抑制剂治疗欠佳的再生障碍性贫血-阵发性睡眠性血红蛋白尿患者的多学科诊疗分析 [PDF]
一例青年男性患者诊断再生障碍性贫血伴阵发性睡眠性血红蛋白尿(paroxysmal nocturnal hemoglobinuria，PNH)，经免疫抑制剂治疗后仅部分缓解。近1年贫血加重、输血依赖，考虑PNH活动性溶血所致，更换依库珠单抗治疗后贫血仍持续加重。详细询问病史发现患者慢性牙周感染，近1个月牙周疼痛溢脓伴发热。多学科讨论考虑慢性牙源性感染激活补体系统是PNH溶血加重的主要原因，急性感染影响了依库珠单抗的疗效。经多学科会诊制定治疗方案，给予静脉抗生素联合牙周冲洗、拔牙控制牙源性感染 ...
刘寅冬 +8 more
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