Results 121 to 130 of about 948,888 (196)

[Analysis of multidrug resistance gene locus mutations and clinical significance in children with Mycoplasma pneumoniae pneumonia]. [PDF]

Zhongguo Dang Dai Er Ke Za Zhi
Zhang W, Wang Y, Cai LJ.
europepmc   +1 more source

基于全球基因组的旱獭埃希菌耐药性分析

Kexin Zhang, Xiaohe Hu, Hu Xiao-He, Chang Jiang, Song Yu, Yue Min, Zhao Guo-Ping, Tang Biao, 复旦大学生命科学学院微生物学系, 上海 200433, 中国   +8 more
openalex   +1 more source

[Carbapenemase Genes, Virulence Genes, and Molecular Epidemiology of Carbapenem-Resistant Klebsiella pneumoniae Derived From Bloodstream Infections]. [PDF]

Sichuan Da Xue Xue Bao Yi Xue Ban
Liao Q, Yuan Y, Zhang W, Deng J, Kang M.
europepmc   +1 more source

[CAMK2a Regulates Paclitaxel Resistance in Oral Squamous Cell Carcinoma Cells by Activating the ERK Signaling Pathway]. [PDF]

Sichuan Da Xue Xue Bao Yi Xue Ban
Wang J, Chen H, Chen J, Feng Y, Yuan Y, Zhang P.   +5 more
europepmc   +1 more source

耐热芽孢杆菌E2菌株纤维素酶基因克隆的研究

, 1995
用质位ｐＢＲ３２２作载体，大肠杆菌Ｅ．ｃｏｌｉＤＨ５αＦ＇作受体，克隆到耐热芽孢杆菌Ｅ２菌株的羧甲基纤维素酶（ＣＭＣａｓｅ）基因。重组质粒ｐＢＧ３从产生ＣＭＣａｓｅ的转化子中分离得到。克隆到的ＣＭＣａｒｅ基因位于４．０ｋｂＨｉｎｄＩＩＩ片段上。功能状态ＣＭＣａｓｅ基因被亚克隆到２．４ｋｂＤＮＡ片段上。同位素杂交结果显示出克隆到的ＣＭＣａｓｅ基因与供体菌染色体ＤＮＡ的亲合性。重组质粒ｐＢＧ３所表达的ＣＭＣａｓｅ的最适作用ｐＨ为６．５，最适作用温度为５５℃，不作用于任何实验过的天然纤维素 ...
张义正, 官家发,范成英,吴恰庆,张发群,江明,张义正   +1 more
core  

[Research Progress on the Application of CRISPR/Cas System in Rapid Testing of Drug-Resistant Bacteria in Clinical Practice]. [PDF]

Sichuan Da Xue Xue Bao Yi Xue Ban
Song Z, Li H, Zhao Y, Li M.
europepmc   +1 more source

家族性渗出性玻璃体视网膜病变的致病基因研究及治疗药物筛选

, 2016
家族性渗出性玻璃体视网膜病变（Familial exudative vitreoretinopathy, FEVR ）是一种严重的遗传性视网膜疾病。该病以视网膜血管发育不完整和新生血管形成为主要特征，可表现为视网膜血管渗漏、牵拉、出血甚至视网膜脱落并最终导致失明。该病的发病原因复杂，研究表明，遗传因素在该病的发病过程中起关键作用，目前已经发现至少5个基因的突变可导致FEVR：NDP, FZD4， LRP5，TSPAN12和ZNF408。然而，这些突变只能解释约50%的FEVR病例 ...
张琳
core  

[Everolimus inhibits malignant phenotype of erdafitinib-resistant bladder cancer cells through the p70S6K/PI3K/MAPK signaling pathway]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Wu H, Jiang Y, Zhang X, Wang S.
europepmc   +1 more source

[A transition from targeting immune evasion to a multidisciplinary collaborative treatment framework for "homotherapy for heteropathy" in liver metastases]. [PDF]

Zhonghua Gan Zang Bing Za Zhi
Zhang Q, Zhang N, Lu YY.
europepmc   +1 more source

[Rapid detection of fluconazole resistance in <i>Candida tropicalis</i> using MALDI-TOF mass spectrometry]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Hou J, Chen W, Peng L, Qiao F, Kang M, Ma Y.   +5 more
europepmc   +1 more source