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老年病毒性肝炎病因学分析 [PDF]

Zhongshan Daxue xuebao. Yixue kexue ban, 1997
摘　要　总结160 例60 岁以上老年性病毒性肝炎的病毒类型,并与100 例20 ～ 35 岁年龄组肝炎进行对照。近 年老年性肝炎组有以下特点:①仍以乙型肝炎为主(占33.8 %);丙型及戊型肝炎各占23.2 %及16 .3%, 较青年组多 见;②重叠肝炎病毒感染多(28/ 160 例, 占17 .5 %),占老年组重症肝炎32.1%。重叠感染中慢性肝炎基础以乙型肝炎 为主, 丙型肝炎少见, 重叠感染中急性肝炎以戊型及丙型多见;③临床类型以急性肝炎、慢性重症肝炎、肝炎肝硬化多 见 ...
赵志新　姚集鲁　黄桂梅　崇雨田　彭文伟
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Correlation analysis of IL‐37 gene polymorphisms and susceptibility to chronic HBV infection among Han people in Central China

International Journal of Immunogenetics, Volume 50, Issue 6, Page 299-305, December 2023., 2023
Abstract Hepatitis B virus (HBV) is responsible for various liver diseases, such as chronic hepatitis B (CHB), liver fibrosis, liver cirrhosis (LC) and hepatocellular carcinoma (HCC), which pose a significant threat to human health. An ineffective immune response to HBV can result in viral chronicity.
Hai Cheng, Fenglan Sun, Yaoling Ouyang, Chengbin Li   +3 more
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Increased glutamate in type 2 diabetes in the Korean population is associated with increased plasminogen levels 韩国2型糖尿病患者谷氨酸升高与纤溶酶原水平升高有关

Journal of Diabetes, Volume 15, Issue 9, Page 777-786, September 2023., 2023
Highlights Increased glutamate is associated with the development of diabetes. Glutamate increases plasminogen (PLG) levels through glutamate metabotropic receptor 5 activation with various insulin resistance‐related stresses. Glutamate inhibits the conversion of PLG to plasmin by increasing plasminogen activator inhibitor‐1.
Hyo Jung Lee, Jeong Won Yeom, Ji Ho Yun, Han Byul Jang, Min‐Gyu Yoo, Hyo‐Jin Kim, Soo Kyung Koo, Hye‐Ja Lee   +7 more
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Electroacupuncture reduces blood glucose by regulating intestinal flora in type 2 diabetic mice 电针通过调节2型糖尿病小鼠肠道菌群降低血糖

Journal of Diabetes, Volume 14, Issue 10, Page 695-710, October 2022., 2022
Highlights Electroacupuncture (EA) regulates the intestinal flora by promoting intestinal motility. EA regulated the intestinal flora to reduce the level of systemic inflammation. EA lowering the blood glucose by the IKKβ/NF‐κB‐JNK‐IRS‐1‐AKT signal pathway.
Jing An, Lingli Wang, Shuangning Song, Lugao Tian, Qingqing Liu, Minhui Mei, Wenhua Li, Shi Liu   +7 more
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Targeting the PI3K/Akt signaling pathway in pancreatic β‐cells to enhance their survival and function: An emerging therapeutic strategy for type 1 diabetes 一种新兴的1型糖尿病治疗策略:靶向胰腺β细胞中的PI3K/Akt信号通路以增强其存活和功能

Journal of Diabetes, Volume 14, Issue 4, Page 247-260, April 2022., 2022
Highlights Phosphoinositide 3‐kinase (PI3K)/Akt signaling is an emerging promising therapeutic target for diabetes. Modulation of the PI3K/Akt signaling pathway, via protein and peptide‐based biologics, parasite‐derived molecules, plant extracts, or through microRNA interactions, will regulate the processes that determine the function of β‐cells and ...
Inah Camaya, Sheila Donnelly, Bronwyn O'Brien   +2 more
wiley   +1 more source

Abstracts

, 2022
Cancer Science, Volume 113, Issue S1, Page 1-1874, February 2022.
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乙型肝炎患者病毒学检验结果分析

Zhongguo shiyan zhenduanxue, 2013
乙型肝炎是由乙型肝炎病毒（HBV）感染机体后所引起的疾病。乙型肝炎病毒是一种嗜肝病毒,主要存在于肝细胞内并损害肝细胞,引起肝细胞炎症、坏死、纤维化。若乙型肝炎感染患者不能及时得到诊断及有效的治疗,最终会发展成为肝硬化、肝癌等严重的肝病,对患者的生命构成着重大的威胁。临床上,乙型肝炎病毒的检验对于乙型肝炎的诊断具有重要的意义。目前 ...
岳志刚
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慢性肝病与肝癌患者性激素水平变化的临床意义

Zhongguo shiyan zhenduanxue, 2008
目的探讨性激素变化与慢性肝病、肝癌发生发展的关系。方法应用放免分析法对128例慢性肝病(慢性肝炎92例、肝炎肝硬化23例、肝硬化并发肝癌13例血清中睾酮（T）、雌二醇（E2）和催乳素（PRL）等进行了测定。结果慢性肝炎重度、肝硬化、肝硬化并发肝癌各组血清T含量明显低于慢性肝炎轻度组及正常对照组（P0.05）,但是,随着慢性肝炎向肝硬化、肝癌进展,慢性肝炎重度、肝硬化、肝硬化并发肝癌各组血清E2/T、E2/PRL水平明显高于慢性肝炎轻度组及正常对照组 ...
陈永胜, 关丽, 邱冰, 段立伟, 田月丽, 李东复   +5 more
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血清总胆汁酸测定对慢性肝炎的诊断价值

Zhongguo shiyan zhenduanxue, 2003
目的　探讨血清总胆汁酸 （TBA）检测对慢性肝炎的诊断价值。方法　针对 130例肝穿刺活检病理证实为慢性肝炎的病人及肝穿刺病理证实为炎症的 2 0例病人 ,应用酶比色法测定血清TBA水平。结果　慢性肝炎组病人血清TBA水平均显著高于无炎症活动的对照组病人 ,且TBA水平与肝炎病理分级呈正相关。结论　血清TBA水平是慢性肝炎诊断的一个敏感指标 ,并有助于判定慢性肝炎病情程度。
杜静, 王欣
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