Results 101 to 110 of about 5,807 (149)

人类自然杀伤细胞对靶细胞的选择性结合

Zhongshan Daxue xuebao. Yixue kexue ban, 1992
采用单个细胞水平细胞毒方法研究比较了正常人外周血自然杀伤(NK)细胞对不同靶细胞结合与杀伤活性的差别。发现NK细胞对人胚胎成纤维细胞和低分化鼻咽癌(CNE-2)细胞的结合率明显高于对人成骨肉瘤细胞(OS-732)和PLC/PRF/5人肝癌细胞,结合并杀伤新鲜切除人肝癌细胞,而对同一病人的癌周肝细胞则无作用;在同一株CNE-2细胞中,NK多选择性地与核浆比例大的靶细胞结合。以上结果说明NK细胞在发挥自然细胞毒过程中具有一定的选择性,选择性地结合并杀伤分化差或幼稚的靶细胞。
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[Hepatitis B virus down-regulates the expression of inhibin and promotes the proliferation and survival of hepatocellular carcinoma cells]. [PDF]

Zhonghua Gan Zang Bing Za Zhi, 2023
Liu JY, Shao JY, Liu Y, Li H, Kong X, Zhao Y, Fan YM, Wu B, Zhao M.   +8 more
europepmc   +1 more source

[Shikonin induces hepatocellular carcinoma cell apoptosis by suppressing PKM2/PHD3/HIF-1α signaling pathway]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao, 2023
Zhang H, Chen Z, Zhao X, Huo Q, Cheng X.
europepmc   +1 more source

[HDAC2-mediated H3K27 acetylation promotes the proliferation and migration of hepatocellular carcinoma cells]. [PDF]

Beijing Da Xue Xue Bao Yi Xue Ban
Tang S, Yang B, Li J, Zhao L, Wang Y, Wang S.   +5 more
europepmc   +1 more source

乙肝病毒X蛋白对肝癌细胞组蛋白H3K4甲基化修饰的影响及机制

Zhongshan Daxue xuebao. Yixue kexue ban, 2013
【目的】 探讨乙肝病毒X蛋白(HBx)与肝癌细胞组蛋白H3K4位点甲基化修饰的关系及其可能的机制?【方法】构建稳定表达HBx基因的HepG2-hbx及载体对照细胞系HepG2-vc,同时培养用于阳性对照的肝癌细胞系HepG2.2.15及阴性对照细胞系HepG2;用酶标法检测各组细胞组蛋白H3K4位点甲基转移酶活性,比较HBx对H3K4位点甲基转移酶活性的影响;qRT-PCR检测各组细胞中H3K4位点特异性甲基转移酶SMYD3 ( SET and MYND domain containing3 ...
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[Angio-associated migratory cell protein is highly expressed in hepatocellular carcinoma and promotes tumor cell invasion and metastasis]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Li C, Yin G, Cheng X, Jiang Y.
europepmc   +1 more source

[Long noncoding RNA HClnc1 promotes proliferation and migration of liver cancer cells by targeting RBBP5/KAT2B complex to enhance ODC1 transcription]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Feng Z, Li W, Zhang M, Wang P, Shuai Y, Zhang H.   +5 more
europepmc   +1 more source

[CENPI promotes the migration of liver cancer cells and the epithelial-mesenchymal transition process by activating the RAS/MEK/ERK signaling axis]. [PDF]

Zhonghua Gan Zang Bing Za Zhi
Lu SS, Huang W, Ge SJ, Chen J, Sheng Y, Liu ZX, Lu CH.   +6 more
europepmc   +1 more source

[NDRG2 inhibits tumorigenesis of hepatocellular carcinoma by regulating metabolism of phospholipids and triglyceride: a metabonomic analysis]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao, 2022
Wang J, Yuan Y, Zhang K, Sun X, Bu X, Dong J, Wu Y, Tian H, Shen L.   +8 more
europepmc   +1 more source

[Biejiajian Pill Regulates Ferroptosis in Hepatocellular Carcinoma Cells via p62/Keap1/NRF2 Signaling Pathway: A Mechanism Study]. [PDF]

Sichuan Da Xue Xue Bao Yi Xue Ban
Chen W, He C, Wen B, Sun H, Yang X, Chen W, Liu Y, Zhong B, He S.   +8 more
europepmc   +1 more source