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Advances of microRNAs Correlated with Invasion and Metastasis of Lung Cancer [PDF]
, 2010 Jiacong YOU, Qinghua ZHOU
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Plectin通过诱导F-actin聚合增强肝癌细胞的迁移能力
Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition目的 研究Plectin的表达与肝癌细胞迁移能力的关系，揭示Plectin表达影响肝癌细胞迁移行为的分子机理。 方法 首先，Western blot检测正常肝细胞和肝癌细胞中Plectin的表达。其次，构建Plectin下调的肝癌细胞株，设立对照组（shNC组）和shPLEC组，各组分别设溶剂对照组（shNC+DMSO组或shPLEC+DMSO组）和F-actin骨架聚合诱导剂Jasplakinolide组（shNC+Jasp组或shPLEC+Jasp组）。采用Western ...
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