Results 51 to 60 of about 2,586 (99)

[A stable mouse model of chronic liver fibrosis induced by vitamin A deficiency and intraperitoneal CCl₄ injection]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Yang T, Zhao L.
europepmc   +1 more source

血清PC-Ⅲ、Ⅳ-C、LN、HA水平对诊断肝纤维化的意义

Zhongguo shiyan zhenduanxue, 1997
用放射免疫法同时测定１１４例肝病患者血清Ⅲ型前胶原（ＰＣ－Ⅲ）、Ⅳ型胶原片段（Ⅳ－Ｃ）、层粘连蛋白（ＬＮ）和透明质酸（ＨＡ）水平。结果表明，慢性肝病组ＰＣ－Ⅲ水平高于正常人（Ｐ＜０．０５），但在慢性肝炎和肝硬化之间无显著性差异（Ｐ＞０．０５）。重度慢性肝炎及肝硬化Ⅳ－Ｃ水平升高较ＰＣ－Ⅲ和ＬＮ显著；中度慢性肝炎时ＬＮ水平即显著升高；急性肝炎时ＨＡ显著升高后，从中度慢性肝炎始ＨＡ水平显著升高（Ｐ＞０．００１），肝硬化时最高。表明血清ＨＡ水平反映肝损伤，病变活动及纤维化程度的敏感性优于ＰＣ－Ⅲ、Ⅳ－Ｃ和ＬＮ，
doaj  

[Clinical characteristics, efficacy and safety of antifibrotic agents in elderly patients with connective tissue disease-associated interstitial lung disease]. [PDF]

Beijing Da Xue Xue Bao Yi Xue Ban
Lan J, Chen Z, Cheng Y, Zhao L.
europepmc   +1 more source

[Protective effect of knock-down the expression of <i>Blimp1</i> gene on early liver injury in CCl₄-induced mouse model of liver fibrosis]. [PDF]

Beijing Da Xue Xue Bao Yi Xue Ban
Qin Q, Li R, Zhou Y, Zhang Y, Han M, Zhu L.   +5 more
europepmc   +1 more source

胆管上皮细胞表达TGF-?茁在胆汁淤积性肝病中的作用

Zhongshan Daxue xuebao. Yixue kexue ban, 2010
【目的】 通过研究胆汁淤积性肝病不同阶段的肝脏病变65380;BDEC增殖及转化生长因β(TGF-β)的变化,以探讨胆汁淤积性肝病发生发展的可能机制65377;【方法】 ①以胆总管结扎(BDL)制作胆汁淤积性肝病大鼠模型,分为正常对照组(D0)65380;7天组(D7)及18天组(D18);②动态观察不同时间点大鼠肝脏病理变化,以Knodell组织学评分评价肝脏组织学改变;③自肝脏中分离BDEC,以实时定量PCR方法(RT-PCR)检测不同时间点肝脏组织以及分离所得BDEC中TGF-β表达的情况 ...
doaj  

[<i>Shenqi Xiezhuo</i> Decoction alleviates renal fibrosis in rats by ameliorating oxidative stress and inflammation through the Rap1/MAPK/FoxO3a signaling pathway]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Lu X, Liu Z, Liu Y, Pang T, Bian R, Guo L, He X.   +6 more
europepmc   +1 more source

[How I treat acquired clotting factor deficiency]. [PDF]

Zhonghua Xue Ye Xue Za Zhi
Zhang L, Gu WJ.
europepmc   +1 more source

[Research progress of hydrogel-based growth factors for treatment of intervertebral disc degeneration]. [PDF]

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi
Huo X, Li Z.
europepmc   +1 more source

[Wound repair strategies of natural polysaccharide hydrogels based on microenvironmental regulation]. [PDF]

Zhonghua Shao Shang Yu Chuang Mian Xiu Fu Za Zhi
Xu FJ, Li Y.
europepmc   +1 more source

[NLRP3 signaling pathway promotes hepatocyte pyroptosis in mice with nonalcoholic steatohepatitis in hypoxic environment]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Luo S, Zhu Q, Yan Y, Ji Z, Zou H, Zhang R, Ba Y.   +6 more
europepmc   +1 more source