目的: 探索促进肝化脾增量及缩短其再生周期的新途径。方法: 应用肝细胞生长因子( PHGF)与三七皂苷( PNGS) 于自体肝细胞脾内移植( IHAP)的动物模型上, 分别于移植术后 2周、12 周时对病理组织学、电镜形态、肝化脾匀浆谷丙转氨酶含 量及脾内肝细胞增殖指数等指标进行观察分析。结果: 移植术后 2周, 三七皂苷组脾内肝细胞水肿、变性程度较轻, 肝化脾匀浆 丙氨酸转氨酶(ALT)含量达( 928. 0±268. 1)U/g,较对照组[( 639. 4±138. 4)U/g] 明显增高(P
doaj
[Research progress on the multidimensional regulation of gut microbiota on metabolism, immunity, and inflammatory response in metabolic associated fatty liver disease]. [PDF]
Wu ST, Lu XL.
europepmc +1 more source
2型糖尿病合并代谢相关脂肪性肝病患者血清同型半胱氨酸与肝纤维化的相关性
目的 探讨2型糖尿病(T2DM)合并代谢相关脂肪性肝病(MAFLD)患者血清同型半胱氨酸(HCY)水平与肝纤维化之间的关联。方法 选取于吉林大学第二医院收治的T2DM同时伴有MAFLD患者214例,采用肝脏超声影像和瞬时弹性技术测定肝脏硬度(LSM)及受控脂肪衰减参数(CAP),再将入选患者分为非肝纤维化组及肝纤维化组,将肝脂肪变性和显著纤维化分别定义为CAP评分≥260 dB/m和LSM评分≥8 kPa。收集全部病人的基本信息,同时测定了空腹血糖、血脂、肝功、同型半胱氨酸等血液指标 ...
李卓奇 +4 more
doaj
[Gut microbiota-associated metabolites with drug-induced liver injury]. [PDF]
Gao WK +5 more
europepmc +1 more source
[Angio-associated migratory cell protein is highly expressed in hepatocellular carcinoma and promotes tumor cell invasion and metastasis]. [PDF]
Li C, Yin G, Cheng X, Jiang Y.
europepmc +1 more source
[Impact of anti-gp210 and anti-centromere antibody dual positivity on clinical prognosis in patients with primary biliary cholangitis: risk analysis and establishment of response criteria]. [PDF]
Luo J +16 more
europepmc +1 more source
[Research progress in the field of liver failure with artificial livers in 2025]. [PDF]
Han T.
europepmc +1 more source
[Clinical outcomes of small-size grafts in auxiliary liver transplantation for the treatment of portal hypertension]. [PDF]
Ju HF +9 more
europepmc +1 more source
[Analysis of the impact of tumor diameter on short-term prognosis in patients with hepatitis B-related hepatocellular carcinoma-inducing acute-on-chronic liver failure]. [PDF]
Peng YH +9 more
europepmc +1 more source
[Study on the role and mechanism of quercetin promoting autophagy in HCCLM3 cells via STING signaling]. [PDF]
Chen L, Wu GZ, Zhu Y, Zhang TT.
europepmc +1 more source

