Results 41 to 50 of about 6,932 (150)

Safety analysis of Yttrium-90 resin microsphere selective internal radiation therapy on malignant liver tumors [PDF]

open access: yes
ObjectiveTo explore the safety of Yttrium-90 resin microsphere selective internal radiation therapy (90Y-SIRT) on malignant liver tumors. MethodsA retrospective analysis was conducted on 64 patients with malignant liver tumors who underwent 90Y-SIRT from
Guanwu WANG   +11 more
core   +1 more source

A dormant cancer mouse model established by combining preimmune strategy with mVenus-p27K- system [PDF]

open access: yes
Objective·To establish a mouse model with dormant cancer and no obvious metastasis by combining the preimmune strategy with the mVenus-p27K- cell G0 phase indicator system, the DTR-HSV/TK suicide gene system, and the Luc2-tdTomato tracer system.Methods ...
CHEN Suyuan   +6 more
core   +1 more source

原发性肝癌患者外周血中肝细胞特异性 AFP mRNA 检测及意义

open access: yesZhongshan Daxue xuebao. Yixue kexue ban, 2000
【目的】寻找一种敏感的方法以检测原发性肝癌患者外周血中肝细胞特异性 AFP mRNA 。【方法】巢式 RT-PCR 检测外周血有核细胞成分中 AFP mRNA。【结果】49 例肝癌中 17 例检出AFP mRNA ,阳性率 35%, 其中 9 例证实有转移的 6 例阳性( 67%)。19 例肝硬化、6 例急性肝炎、8 例慢性肝炎、5例肝良性肿瘤、6 例肝内胆管癌、11 例肝转移癌、13 例健康对照 组均为阴性。外周血细胞 AFP mRNA 的存在与肝内肿癌灶的数目、是否有门静脉癌栓形成 ...
袁育红, 胡品津
doaj  

[SWI/SNF Complex Gene Mutations Promote the Liver Metastasis 
of Non-small Cell Lung Cancer Cells in NSI Mice]. [PDF]

open access: yesZhongguo Fei Ai Za Zhi, 2023
Gao L   +16 more
europepmc   +1 more source

AIDA通过内质网相关的蛋白质降解途径选择性下调脂肪合成途径的代谢酶从而减缓肠道脂肪吸收并防止肥胖发生 [PDF]

open access: yes, 2019
文章简介肠道对膳食脂肪吸收的效率是个人是否易患肥胖的主要决定因素之一。然而,目前人们还不清楚脂肪吸收是如何受调控并导致肥胖的。本研究表明,抑制内质网相关的蛋白质降解途径会提高甘油三酯合成途径的数个代谢酶的水平,并促进小肠对脂肪的吸收。包含C2结构域的蛋白AIDA作为一个重要国家重点基础研发计划;;\n国家自然科学基金 ...
Chen-Song Zhang   +17 more
core  

Yttrium-90 selective internal radiation therapy on liver cancer: the past, the present, and the future [PDF]

open access: yes
Yttrium-90 selective internal radiation therapy (90Y-SIRT) is a treatment technique that delivers radioactive microspheres precisely to the arterial vascular bed of neoplasms, utilizing beta radiation to administer a high local dose of radiation to the ...
Jiabin CAI   +8 more
core   +1 more source

膜型基质金属蛋白酶一1 在肝癌组织中的表达及意义

open access: yesZhongshan Daxue xuebao. Yixue kexue ban, 2005
【目的】比较膜型基质金属蛋白酶-1(membrane type-1 matrix metalloproteinase,MT1-MMP)在大肝癌(瘤体直径>3cm)及小肝癌(单肿瘤结节且瘤体直径≤3cm)组织中的表达差异,并探讨其在肝癌肿瘤细胞浸润、转移过程中的作用。【方法】应用半定量RT-PCR方法检测MT1-MMP mRNA在22例大肝癌及12例小肝癌组织中的表达;应用免疫组化方法检测MT1-MMP蛋白在53例大肝癌及40例小肝癌组织中的表达,并分析MT1-MMP蛋白表达水平与肝癌浸润、转移之间的关系。
何萍   +4 more
doaj  

手术前血清癌胚抗原与胃癌预后的关系 [PDF]

open access: yes, 1988
癌胚抗原(CEA)测定作为消化道癌肿的一种诊断方法,由于其敏感性及特异性不强,其意义为大多数作者所否定,但在判断预后,估计手术后存活期和监视手术后癌肿复发等方面的作用,已经受到普遍的重视。有关手术前血清CEA水平与癌肿预后的关系,国外报道以大肠癌较多,胃癌较少。本文旨在探讨术前CAE测定与胃癌预后的关系。 材料和方法 一、病例资料 研究对象为1984年7月至1987年3月我院胃肠外科组收治的病理组织学为腺癌的胃癌96例,由于其他原因而手术前未测定血清CEA的病例未包括在内。96例中,男71例,女25例 ...
詹文华
core  

A New Chapter in Colorectal Cancer Treatment: Insights from 2024 ASCO Annual Meeting [PDF]

open access: yes
At the 2024 Annual Meeting of the American Society of Clinical Oncology (ASCO), multiple research achievements in the field of colorectal cancer were announced. This article summarizes and interprets the research results related to colorectal cancer from
Guanghai DAI, Miaomiao GOU, Zhikuan WANG
core   +1 more source

谷胱甘肽巯基转移酶基因多态性在原发性肝细胞癌人群中的研究

open access: yesZhongguo shiyan zhenduanxue, 2012
目的探讨原发性肝细胞癌人群中谷胱甘肽巯基转移酶基因多态性与肝癌发生、发展的关系。方法我院2008年10月-2010年4月收治的原发性肝癌患者与健康体检者各150名,提取血样,利用多重PCR和限制性片段长度多态性检测法分别检测肝癌人群与体检健康者的谷胱甘肽巯基转移酶基因多态性,并进行对比分析。结果该肝癌人群中:谷胱甘肽巯基转移酶基因多态性型别在病例和对照组研究对象中出现的频率无显著性差别,P>0.05;GSTM1-null、GSTT1-null、GST01-Ala140Asp、GSTP1 ...
唐耘天   +5 more
doaj  

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