Results 11 to 20 of about 2,026 (114)

Time‐limited diets and the gut microbiota in cardiometabolic disease 限时进食及肠道菌群在心脏代谢性疾病中的作用

open access: yesJournal of Diabetes, Volume 14, Issue 6, Page 377-393, June 2022., 2022
Highlights Time‐specific diet is a novel nutritional approach to prevent and treat cardiometabolic disease. Feeding‐fasting cycles shape gut microbial composition and metabolite production. These alterations may play a causative role in driving the cardiometabolic benefits of intermittent fasting.
Karina Ratiner   +3 more
wiley   +1 more source

Ceramide changes in abdominal subcutaneous and visceral adipose tissue among diabetic and nondiabetic patients 糖尿病和非糖尿病患者腹部皮下和内脏脂肪组织神经酰胺的变化

open access: yesJournal of Diabetes, Volume 14, Issue 4, Page 271-281, April 2022., 2022
Highlights The gender‐specific role of sphingolipids in obesity‐related metabolic dysfunctions is unclear. The aim of this study is to identify ceramide species by liquid chromatography‐mass spectrometry that accumulate in central fat in relation to status of diabetes and gender for subjects with a body mass index ≥40 kg/m2 or > 35 kg/m2 with ...
Michelle Brusatori   +7 more
wiley   +1 more source

MMC celebrating 6 years of experience and expansion 庆祝MMC六年的经验和壮大

open access: yes, 2022
Journal of Diabetes, Volume 14, Issue 5, Page 356-357, May 2022.
Itamar Raz
wiley   +1 more source

COVID‐19 and comorbidities: A role for dipeptidyl peptidase 4 (DPP4) in disease severity? 新冠肺炎与合并症:二肽基肽酶4在疾病严重程度中的作用?

open access: yesJournal of Diabetes, Volume 12, Issue 9, Page 649-658, September 2020., 2020
Highlights Coronavirus disease 2019 (COVID‐19) is caused by SARS‐CoV‐2; recent modeling of the structure of SARS‐CoV‐2 spike glycoprotein, which mediates viral‐host‐cell entry, predicts interactions with dipeptidyl peptidase 4 (DPP4) in addition to angiotensin‐converting enzyme 2.
Margaret F. Bassendine   +3 more
wiley   +1 more source

The Jiangnan diet, a healthy diet pattern for Chinese 江南饮食——一种健康的中国传统饮食模式

open access: yesJournal of Diabetes, Volume 12, Issue 5, Page 365-371, May 2020., 2020
Highlights To explore the localized “Mediterranean diet” for metabolic disorders prevention in China, we review the main healthy diet components, which the native inhabitants in the Yangtze River Delta region have eaten for a long time, and refer to this healthy diet as “Jiangnan Diet.” Abstract Geographically, the Qinling Mountain—Huai River line ...
Jiqiu Wang   +3 more
wiley   +1 more source

Nutritional Therapy for Obesity in Children and Adolescent(儿童青少年肥胖的营养治疗策略) [PDF]

open access: yesShipin kexue jishu xuebao, 2020
Obesity has become a public health problem. Obesity in children and adolescents has obtained growing social attention. Body mass index (BMI) is widely used to identify overweight and obesity.
YANG Jiongxian(杨炯贤)   +1 more
doaj   +1 more source

右美托咪定在病态肥胖患者减重手术中的应用研究进展

open access: yesZhongguo shiyan zhenduanxue, 2021
近年来,随着治疗技术的不断提升,减重代谢手术已成为治疗病态肥胖的首选治疗方法,然而,肥胖患者仍会伴随很多相关并发症,如心脑血管疾病、呼吸系统疾病、关节肌肉疾病以及代谢相关综合征,上述并发症在围术期给麻醉医生带来极大的挑战,并严重影响着手术结果。麻醉用药右美托咪定是一种新型a2肾上腺素受体激动剂,其独特药理和代谢的特点,使得右美托咪定在临床麻醉中的应用更加广泛,但目前其在肥胖患者减重手术中的相关研究鲜少。本文将围绕右美托咪定在病态肥胖患者减重代谢手术中的应用进展作一概述。
俞贝贝   +4 more
doaj  

Renoprotective effects of brown adipose tissue activation in diabetic mice 棕色脂肪激活对糖尿病小鼠的肾脏保护作用

open access: yesJournal of Diabetes, Volume 11, Issue 12, Page 958-970, December 2019., 2019
Highlights This study demonstrates that of brown adipose tissue (BAT) with CL316,243 attenuates the progress of diabetic kidney disease (DKD). Mechanistically, the activation of BAT improved concentrations of circulating adipokines and microRNAs, which further affected the diabetic kidney and reactivated the AMP‐activated protein kinase/sirtuin 1 ...
Ying‐Ying Cai   +10 more
wiley   +1 more source

International clinical practice recommendations on the definition, diagnosis, assessment, intervention, and psychosocial aspects of developmental coordination disorder – Chinese (Mandarin) translation

open access: yesDevelopmental Medicine &Child Neurology, Volume 61, Issue 3, Page E1-E35, March 2019., 2019
目的 本国际临床指南由欧洲残疾儿童学会(the European Academy of Childhood Disability,EACD)牵头制定,旨在解决发育性协调障碍(developmental coordination disorder,DCD)的定义、诊断、评估、干预以及与社会心理方面的临床应用关键问题。 方法 本指南针对五个领域的关键问题,通过文献综述和专家团队的正式讨论达成共识。为保证指南的循证基础,以“机制”、“评估”和“干预”为检索词, 对2012年更新以来提出的最新建议以及新增的“社会心理问题”和“青少年/成人”为检索词进行检索。根据牛津大学循证医学中心证据等级 (证据水平 [level of evidence, LOE]1–4) 将结果进行分类,最终转化为指南建议。并由国际 ...
Jing Hua   +6 more
wiley   +1 more source

FTO、MC4R、SH2B1与肥胖T2DM的关联及基因间交互作用研究

open access: yesZhongguo shiyan zhenduanxue, 2021
2型糖尿病(T2DM)是由遗传和环境因素引起的复杂疾病。目前,全球有4.63亿糖尿病患者,到2045年糖尿病的发病人数将增加到7亿[1]。在中国,糖尿病的发病率为10.9%,在超重和肥胖人群中,该值甚至更高[2]。有研究显示糖尿病和肥胖症可以独立遗传亦可共同遗传,甚或糖尿病是引起肥胖的病因[3]。肥胖者体内的非酯化脂肪酸、细胞因子、促炎性标志物等水平的升高与胰岛素抵抗发生发展相关,这些因素可导致T2DM的发生[4]。因此,阐明糖尿病的发病机制非常重要。
耿力, 连明珠, 赵莹, 陈琰
doaj  

Home - About - Disclaimer - Privacy