Results 11 to 20 of about 147,414 (157)
Zhongshan Daxue xuebao. Yixue kexue ban, 2019 【目的】探索合并肥胖的痛风患者临床特征及尿酸排泄特点。【方法】纳入2013年1月至2018年5月在中山大学孙逸仙纪念医院风湿免疫科住院的痛风患者228例，收集临床资料及空腹血生化指标，测定24h尿尿酸和尿肌酐并计算肾尿酸排泄指标。【结果】根据体质量指数（BMI）把患者分为肥胖组（n=44）、超重组（n=88）及非超重组（n=96），肥胖组年龄小于超重组及非超重组［43（32，57）岁比55（45，65）岁、58（45，67）岁］，起病年龄小于非超重组［37（26，48）岁比48（38，59）岁 ...
梁锦坚
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Zhongshan Daxue xuebao. Yixue kexue ban, 2015 【目的】 分析大于6岁肥胖儿童代谢综合征的临床特征及其代谢成分异常的相关性分析?【方法】 收集2008-2011年在我院儿科门诊确诊为单纯性肥胖症的儿童的临床资料,检测空腹血脂?空腹血糖,计算胰岛素抵抗指数?以我国2012年6月最新制定的中国儿童青少年代谢综合征定义及诊断建议为标准,根据其代谢异常指标数量的不同,将 > 6岁的肥胖儿童分为1项指标组?2项指标组和 ≥ 3项指标组进行比较分析?【结果】 > 6岁的单纯性肥胖儿童119例,其平均年龄(10.7 ± 2.1)岁,≥3项指标组21(17.65 ...
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肥胖相关慢性炎症与代谢性脑血管病 Obesity-Related Chronic Inflammation and Cerebro-Metabolic Disease
Zhongguo cuzhong zazhi脑血管病目前已成为全球第二大死亡原因，其发病风险主要归因于代谢紊乱。本文就肥胖相关慢性炎症与代谢性脑血管病的发病机制进行综述。肥胖状态下免疫细胞聚集、促炎因子分泌增加、血管内皮损伤等是代谢性脑血管病的重要致病机制。以炎症为治疗靶点的生活方式干预、药物免疫治疗及减重抗炎治疗等新型、有效的防治策略，有望为降低代谢性脑血管病的发病率，提高患者的生存率和生活质量提供参考依据。 Abstract: Cerebrovascular disease has become the second cause of ...
梁小雪, 郭黎 LIANG Xiaoxue, GUO Li
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Linchuang shenzangbing zazhi, 2015 糖尿病肾病(diabetic nephropathy,DN)是糖尿病严重的并发症,且发病率高,已成为糖尿病患者死亡的主要原因[1]。笔者结合肥胖体质DN的中医证候特点,在西药常规治疗的基础上加用复方肾炎片治疗肥胖体质DN,取得较好疗效,现报道如下。资料与方法一、研究对象选择2008年5月至2012年3月在延安大学咸阳医院内分泌科住院及门诊随访患者63例。所有患者均符合下列条件:(1 ...
涂小刚 +5 more
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Journal of Diabetes, Volume 15, Issue 12, Page 1020-1028, December 2023., 2023 Highlights Childhood obesity was significantly associated with the increased risk of insulin resistance (IR). There were 12 metabolites co‐associated with childhood obesity and IR, including seven amino acid and five fatty acid metabolites. The combination of body mass index standard deviation score and key metabolites could effectively predict the ...
Wu Yan +5 more
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Journal of Diabetes, Volume 15, Issue 10, Page 900-910, October 2023., 2023 Highlights Mild acquired impaired thyroid hormone sensitivity was widespread among the general populations. Reduced thyroid hormone sensitivity was related with metabolic syndrome and its components. Impaired thyroid hormone sensitivity might affect the distribution of adipose tissue and muscle.
Fang Lv +6 more
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Journal of Diabetes, Volume 15, Issue 9, Page 787-798, September 2023., 2023 Highlights Laparoscopic sleeve gastrectomy and laparoscopic Roux‐en‐Y gastric bypass are effective for reducing weight and improving metabolic parameters in Chinese patients with obesity. These interventions resulted in improved glycemic control, as evidenced by decreased glycated hemoglobin levels, reduced insulin resistance, and improved ...
Wenhuan Feng +6 more
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Mechanisms of bariatric surgery for weight loss and diabetes remission 减重手术减轻体重和缓解糖尿病的机制
Journal of Diabetes, Volume 15, Issue 9, Page 736-752, September 2023., 2023 Highlights Controversial changes in intestinal hormones after bariatric surgery (BS) were summarized. The changes of signaling proteins involved in insulin resistance and the newly proposed changes in growth differentiation factor 15, exosomes, and extracellular vesicles after BS were elucidated.
Mengsha Yin +6 more
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Journal of Diabetes, Volume 15, Issue 8, Page 674-684, August 2023., 2023 Highlights In people with type 2 diabetes, the risk of all‐cause, cardiovascular disease, and cancer mortality increased with higher gamma‐glutamyl transferase (GGT) concentrations. Stronger effects of GGT levels and all‐cause mortality were observed in the group with body mass index <25 kg/m2 and those with dyslipidemia.
Haoyu Guan +12 more
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Journal of Diabetes, Volume 15, Issue 6, Page 496-507, June 2023., 2023 Highlights Using a large‐scale prospective population‐based cohort study, we found that a higher frequency of daytime napping is associated with an increased risk of incident type 2 diabetes (T2D), and such relations are modified by body fat percentage (BFP) and C‐reactive protein (CRP) levels.
Rui Zhou +9 more
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