Zhongshan Daxue xuebao. Yixue kexue ban, 2019 【目的】探讨生命早期不同营养状态对宫内发育迟缓（IUGR）雌性大鼠体质量生长追赶、青春发育启动及肥胖的影响。【方法】SPF母鼠孕期限制饮食法建立仔鼠IUGR模型，采用雌性仔鼠进行实验，IUGR仔鼠哺乳期以小窝喂养（SL-IUGR）模拟过度喂养，同时设IUGR仔鼠常规哺乳（CF-IUGR），正常对照组仔鼠常规哺乳（NC），3组仔鼠均在21d断乳后以基础饲料喂养，分别于仔鼠生后1、7、14、21、35、42和75d称体质量，记录阴门开启时间，21、35d采血检测雌二醇（E2）、黄体生成素（LH）、卵泡雌激素（
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