Results 91 to 100 of about 3,166 (145)

过表达eNOS的MSCs移植抑制肺动脉高压大鼠NF-κB表达

Zhongguo shiyan zhenduanxue, 2016
目的研究过表达eNOS的骨髓间充质干细胞（MSCs）移植对肺动脉高压（PAH）大鼠的NF-κB影响。方法构建过表达eNOS基因骨髓间充质干细胞;成年雄性Sprague Dawley大鼠,建立分流性PAH模型36只,每组12只,Shunt组;MSCs组;MSCs+eNOS组,正常大鼠为Control组。由中心静脉注入细胞,2周后进行测定血流动力学指标及肺组织病理变化,westernblot及荧光定量PCR测定肺组织表达NF-κB的变化。结果 MSCs移植能降低右心室收缩压,减轻肺病理改变,MSCs ...
赵科研, 郭晓东, 李红岩, 佟昌慈, 张玉彪, 王辉山, 侯明晓   +6 more
doaj  

血管紧张素-(1-7)对野百合碱所致肺动脉高压的影响

Zhongshan Daxue xuebao. Yixue kexue ban, 2009
【目的】 探讨血管紧张素-(1-7)[Ang-(1-7)]对野百合碱 (MCT)诱导的肺动脉高压的作用及相关机制65377;【方法】 雄性Sprague-Dawley大鼠80只随机分为: 正常对照组(control)65380;MCT组65380;MCT + Ang-(1-7)组65380;control + Ang-(1-7)组65377;MCT组和MCT + Ang-(1-7)组颈静脉注射MCT 60 mg/kg,24 h后经微泵持续泵入生理盐水或Ang-(1-7) (24 μg8226;kg ...
doaj  

Sotatercept and pulmonary arterial hypertension. [PDF]

Zhong Nan Da Xue Xue Bao Yi Xue Ban
Tan Y, Chen Y, Li J.
europepmc   +1 more source

[Tanshinone IIA alleviates monocrotaline-induced pulmonary hypertension in rats through the PI3K/Akt-eNOS signaling pathway]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao, 2022
Zhang X, Liu S, Sun Y, Li G.
europepmc   +1 more source

[NDUFAF2 gene mutation presenting as primary pulmonary hypertension: a case report]. [PDF]

Zhongguo Dang Dai Er Ke Za Zhi
Yan XD, Chen YY, Tao L.
europepmc   +1 more source

12例原发性肺动脉高压症临床病理分析 [PDF]

, 1989

core  

[Rosa laevigata Michx. inhibits pulmonary arterial smooth muscle cell proliferation in hypertension by modulating the Src-AKT1 axis]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Yang Z, Lü C, Dong Z, Ji S, Bi S, Zhang X, Wang X.   +6 more
europepmc   +1 more source

先天性心脏病合并肺高压术后肺高压危象

Zhongshan Daxue xuebao. Yixue kexue ban, 1999
目的: 了解先天性心脏病(先心病)并肺动脉高压症(肺高压)术后肺高压危象的发生发展。方法: 总结 50 例 14 岁以下先心病合并中、重度肺高压病人心内畸型矫治术后的早期经过,术后出现肺高压危象情况, 其中 37 例行肺活检。结果: 术后出现肺高压危象 9例, 18次, 半数危象出现在术后 24 h 以内。中度肺高压的病人术后出现危象的比例高于重度者, 危象 倾向于多次发生。危象病人的肺活检病理 Heath-Edwards 分级均为轻、中度改变。危象的发生近半数( 44%)有呼吸道刺激的 诱因 ...
doaj  

[Research progress on bioinformatics in pulmonary arterial hypertension]. [PDF]

Zhongguo Dang Dai Er Ke Za Zhi
Peng W, Zhang ZY, Xiao YB.
europepmc   +1 more source

COMPERA 2.0 risk stratification in patients with severe aortic stenosis: implication for group 2 pulmonary hypertension. [PDF]

J Zhejiang Univ Sci B
Cai Z, Qi X, Zhou D, Dai H, Yidilisi A, Zhong M, Deng L, Guo Y, Fan J, Zhu Q, He Y, Li C, Liu X, Wang J.   +13 more
europepmc   +1 more source