Results 1 to 10 of about 1,072 (164)
Zhongshan Daxue xuebao. Yixue kexue ban, 2004 目的】探讨新生儿重症监护室(NICU)院内感染病原菌及其耐药性变化。【方法】分析近3年88例培养阳性的新生儿NICU内感染致病菌及其对抗生素的耐药性。【结果】共检出病原菌107株,革兰阴性杆菌94株(87.9%),革兰阳性球菌13株(12.1%)。革兰阴性杆菌以肺炎克雷伯杆菌最常见,产ESBL菌株比例高,占60%(24/40)。大肠杆菌产ESBL株占40%(4/10)。革兰阴性杆菌对青霉素类、头孢菌素类和氨基糖苷类抗生素耐药率均高(44.6%～79.5%),显著高于添加β-内酰胺酶抑制剂的抗生素 ...
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Analysis of global burden of bacterial infections: an interpretation of Global mortality associated with 33 bacterial pathogens in 2019 [PDF]
, 2023 The Global Burden of Bacterial Infections report showed that in 2019, there were approximately 13.7 million deaths worldwide due to infection (95% UI ranging from 10.9 million to 17.1 million), and bacterial infection related deaths accounted for 13.6 ...
ZHANG Ying, JIANG Xiaofei
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Non-clostridial Gas-forming Infection in Diabetes：Clinical Analysis of Two Cases [PDF]
, 2022 Non-clostridial organism can produce pneumoderma by breaking down sugar and other substrates in necrotic tissues, and non-clostridial gas-forming infection is usually seen in diabetic patients with poor glycemic control.
WU Yuan, LYU Hongjun, YAO Xiaoli, LIU Juan
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Distribution of blood culture pathogens and clinical characteristics in children with acute leukemia complicated with septic shock [PDF]
, 2022 Objective To explore the distribution of blood culture pathogens and clinical characteristics in children with acute leukemia complicated with septic shock.
Liu Tinghua, Lei Jiaying, Mai Yougang
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Analysis of characteristics of infectious pathogens in malignant tumors combined with bloodstream infection and significance of serum glucose detection [PDF]
, 2023 Background and purpose: The incidence rate of bloodstream infection (BSI) in patients with malignant tumor increases gradually with the progress of anti-tumor treatment. The treatment outcome is closely related to the infection of pathogen.
CHEN Zhujun, DING Zhimin, MA Xiaolu, WANG Yanchun, HU Haoyun, LU Renquan, GUO Lin
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The molecular biological characteristics of Vibrio vulnificus isolated in Guangzhou [PDF]
, 2023 ObjectiveTo investigate the molecular and biological characteristics of Vibrio vulnificus （V. vulnificus）isolated from Guangzhou.MethodsThirty-eight strains of V. vulnificus were collected from Guangzhou， and whole-genome sequences were obtained.
BAI Zhijun +6 more
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野生动物学报, 2022 为探究梅花鹿源肺炎克雷伯氏菌有效的防控和治疗方法，分别采集动物园内呼吸困难的梅花鹿（Cervus nippon）的咽拭子，以及死亡梅花鹿的肺脏、心血、肝脏等病料组织76份，采用细菌分离鉴定和PCR方法进行肺炎克雷伯菌（Klebsiella pneumoniae）分离鉴定，采用人工感染动物性试验、K-B药敏纸片法分别检测其致病性和耐药性。结果显示：从采集的76份病料组织样品分离得到52株肺炎克雷伯菌，其中40株对小白鼠具有致病性。分离的40株致病性肺炎克雷伯菌对阿莫西林、氨苄西林 ...
王炜强孙浩云杨志松
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, 2018 目的了解医院血培养病原菌的菌种分布及常见病原菌的耐药情况,为临床用药提供参考依据。方法对2017年1～12月临床送检的血培养标本进行回顾性统计分析。结果 4 447份血培养标本共分离出病原菌225株,阳性检出率为5. 1%。主要病原菌:大肠埃希菌82株占36. 4%、凝固酶阴性葡萄球菌31株占13. 8%、肺炎克雷伯菌17株占7. 6%、铜绿假单胞菌10株占4.
廖蕴惠, 赵军
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Zhongguo shiyan zhenduanxue, 2022 近年来，由于对抗菌药物特别是广谱头孢菌素的不合理使用，肺炎克雷伯菌对常用抗菌药物的耐药性不断增加。全国细菌耐药监测报告显示碳青霉烯耐药肺炎克雷伯菌（CRKP）的检出率呈现上升趋势。本文收集了北京中医药大学东直门医院2019年1月～2021年12月间从临床标本中分离的肺炎克雷伯菌，并对其分布特征和抗菌药物敏感性进行了分析，为临床医院感染的预防和控制提供参考依据。
杨琦 +5 more
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, 2018 抗生素发现\"黄金时代\"的结束以及日趋严重的抗生素耐药性问题给我们留下一个戏剧性的、缺乏新型药物来防治耐药病原体感染的难题。这使得从现有非抗生素药物中筛查抗菌活性药物成为一种新尝试。近期研究表明:美国食品药品监督管理局(FDA)批准的、本来用于治疗高血钙的药物硝酸镓具有良好的抗菌活性。不同于其他抗生素,镓的药理性质依靠化学拟态,它可以在目标酶分子中取代铁,从而干扰、扰乱细菌含铁蛋白的功能及细菌代谢,无论是在体外实验还是在体内实验中,镓对多种病原体,包括多重耐药病原体都表现出杀菌活性 ...
刘周 +6 more
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